CAS 132907-72-3: Ramosetron Hydrochloride

Description: Ramosetron Hydrochloride is a selective serotonin 5-HT3 receptor antagonist primarily used in the management of nausea and vomiting, particularly in patients undergoing chemotherapy or surgery. It is characterized by its ability to block the action of serotonin at these receptors, which play a crucial role in the vomiting reflex. The compound is typically administered orally or intravenously, depending on the clinical scenario. Ramosetron is known for its relatively long half-life, allowing for less frequent dosing compared to some other antiemetics. Its chemical structure includes a piperidine ring, contributing to its pharmacological properties. The hydrochloride salt form enhances its solubility and stability, making it suitable for pharmaceutical formulations. Common side effects may include headache, constipation, and dizziness, although it is generally well-tolerated. As with any medication, its use should be guided by a healthcare professional, considering potential interactions and contraindications. Overall, Ramosetron Hydrochloride represents an important option in the therapeutic arsenal against nausea and vomiting.

Formula: C₁₇H₁₇N₃O·ClH

InChI: InChI=1S/C17H17N3O.ClH/c1-20-9-13(12-4-2-3-5-16(12)20)17(21)11-6-7-14-15(8-11)19-10-18-14;/h2-5,9-11H,6-8H2,1H3,(H,18,19);1H/t11-;/m1./s1

InChI key: InChIKey=XIXYTCLDXQRHJO-RFVHGSKJSA-N

SMILES: Cl.O=C(C1=CN(C=2C=CC=CC12)C)C3CC=4NC=NC4CC3

Synonyms:

• (-)-(R)-5-[(1-Methyl-1H-indol-3-yl)carbonyl]-4,5,6,7-tetrahydro-1H-benzimidazole monohydrochloride
• (1-methyl-1H-indol-3-yl)[(6R)-4,5,6,7-tetrahydro-1H-benzimidazol-6-yl]methanone hydrochloride (1:1)
• (R)-(-)-Ramosetron hydrochloride
• Irribow
• Methanone, (1-methyl-1H-indol-3-yl)(4,5,6,7-tetrahydro-1H-benzimidazol-5-yl)-, monohydrochloride, (R)-
• Methanone, (1-methyl-1H-indol-3-yl)[(5R)-4,5,6,7-tetrahydro-1H-benzimidazol-5-yl]-, monohydrochloride
• Methanone, (1-methyl-1H-indol-3-yl)[(6R)-4,5,6,7-tetrahydro-1H-benzimidazol-6-yl]-, hydrochloride (1:1)
• Ramosetron HCl
• Ym 060
• Ramosetron hydrochloride

Methanone, (1-methyl-1H-indol-3-yl)[(6R)-4,5,6,7-tetrahydro-1H-benzimidazol-6-yl]-, hydrochloride (1:1)

CAS: 132907-72-3

• Formula: C₁₇H₁₈ClN₃O
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 315.7973

Ramosetron hydrochloride

CAS: 132907-72-3

• Formula: C₁₇H₁₈ClN₃O
• Molecular weight: 315.80

Ramosetron hydrochloride

CAS: 132907-72-3

Ramosetron hydrochloride (YM-060) is a serotonin 5-HT3 receptor antagonist. It is used to treat diarrhea-predominant …

• Formula: C₁₇H₁₈ClN₃O
• Purity: 99.95%
• Color and Shape: Solid
• Molecular weight: 315.8

Ramosetron Hydrochloride

CAS: 132907-72-3

Stability Hygroscopic Applications Selective serotonin 5HT3, receptor antagonist; structurally different from Ondansetron (O655000), Granisetron (G780000). …

• Formula: C₁₇H₁₇N₃O·ClH
• Color and Shape: Neat
• Molecular weight: 315.80

Ramosetron hydrochloride

CAS: 132907-72-3

5-HT3 serotonin receptor antagonist

• Formula: C₁₇H₁₇N₃O•HCl
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 315.8 g/mol