CAS 133-59-5

2-Methylbenzenesulfonyl chloride

Description:

2-Methylbenzenesulfonyl chloride, also known as toluenesulfonyl chloride, is an aromatic sulfonyl chloride characterized by the presence of a sulfonyl group (-SO2Cl) attached to a methyl-substituted benzene ring. This compound is typically a colorless to pale yellow liquid with a pungent odor. It is highly reactive, particularly with nucleophiles, making it a valuable reagent in organic synthesis for the introduction of sulfonyl groups into various substrates. The presence of the sulfonyl chloride functional group allows for the formation of sulfonamides and other derivatives through nucleophilic substitution reactions. Additionally, 2-Methylbenzenesulfonyl chloride is soluble in organic solvents such as dichloromethane and ether but reacts vigorously with water, releasing hydrochloric acid and forming the corresponding sulfonic acid. Due to its reactivity and potential hazards, including corrosiveness and toxicity, it should be handled with appropriate safety precautions in a well-ventilated environment.

Formula: C₇H₇ClO₂S

InChI: InChI=1S/C7H7ClO2S/c1-6-4-2-3-5-7(6)11(8,9)10/h2-5H,1H3

InChI key: InChIKey=HDECRAPHCDXMIJ-UHFFFAOYSA-N

SMILES: S(Cl)(=O)(=O)C1=C(C)C=CC=C1

Synonyms:

• 2-Methylbenzene-1-sulfonyl chloride
• 2-Methylbenzenesulfonyl Chloride
• 2-Methylphenylsulfonyl chloride
• 2-Toluenesulfonyl chloride
• Benzenesulfonyl chloride, 2-methyl-
• NSC 9354
• o-Methylbenzenesulfonyl chloride
• o-Toluenesulfonyl chloride
• o-Toluenesulphonyl chloride
• o-Tolylsulfonyl chloride
• o-Tosyl chloride

o-Toluenesulfonyl Chloride (contains ca. 23% isomer)

CAS: 133-59-5

Formula: C₇H₇ClO₂S

Purity: >75.0%(GC)

Color and Shape: Colorless to Light yellow clear liquid

Molecular weight: 190.64

Ref: 3B-T0284

o-Toluenesulfonyl chloride, 80%

CAS: 133-59-5

o-Toluenesulfonyl chloride is used in organic synthesis and saccharin production. It is also used as pharmaceutical intermediate. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy b

Formula: C₇H₇ClO₂S

Purity: 80%

Color and Shape: Liquid, Clear colorless to yellow

Molecular weight: 190.64

Ref: 02-L18983

2-Methylbenzenesulphonyl chloride

CAS: 133-59-5

2-Methylbenzenesulphonyl chloride

Formula: C₇H₇ClO₂S

Purity: 95%

Color and Shape: clear. colourless liquid

Molecular weight: 190.64728g/mol

Ref: 54-OR9961

2-Toluenesulfonyl chloride(contains ca.23% isomer)

CAS: 133-59-5

2-Toluenesulfonyl chloride is a cationic monomer that polymerizes with amines to form a water-soluble polymer. It is an amide that can be used as a diagnostic agent in animals, as it has been shown to bind to the primary amino groups of proteins. 2-Toluenesulfonyl chloride also inhibits inflammatory diseases and autoimmune diseases, and may be useful for the treatment of both conditions. The mechanism of action is not yet known, but this drug has been shown to inhibit enzymes such as fatty acid synthetase and protein kinase C. This agent may have potential as a therapeutic agent for rheumatoid arthritis or Crohn's disease.

Formula: C₇H₇ClO₂S

Purity: 75%Min

Color and Shape: Clear Liquid

Molecular weight: 190.65 g/mol

Ref: 3D-FT164705