CAS 1332879-52-3

Formula: C20H13BrN2O3S2

InChI: InChI=1S/C20H13BrN2O3S2/c21-15-10-8-13(9-11-15)12-17-19(24)22-20(27-17)23-28(25,26)18-7-3-5-14-4-1-2-6-16(14)18/h1-12H,(H,22,23,24)/b17-12-

InChI key: CGDLWHGPJPVPDU-ATVHPVEESA-N

SMILES: C1=CC=C2C(=C1)C=CC=C2S(=O)(=O)/N=C/3\NC(=O)/C(=C/C4=CC=C(C=C4)Br)/S3

Clathrin-IN-1

CAS: 1332879-52-3

Pitstop 2 inhibits clathrin-mediated endocytosis, targeting clathrin's terminal domain, with potential in cancer research.

Formula: C₂₀H₁₃BrN₂O₃S₂

Purity: 99.53%

Color and Shape: Solid

Molecular weight: 473.363

Ref: TM-T9063

Clathrin-IN-1

CAS: 1332879-52-3

Clathrin-IN-1

Formula: C₂₀H₁₃BrN₂O₃S₂

Purity: ≥98%

Molecular weight: 473.36

Ref: 54-BUP12466

N-[5-[(4-Bromophenyl)methylene]-4,5-dihydro-4-oxo-2-thiazolyl]-1-naphthalenesulfonamide

CAS: 1332879-52-3

Formula: C₂₀H₁₃BrN₂O₃S₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 473.3628

Ref: IN-DA01LJ2J

Pitstop2

CAS: 1332879-52-3

Pitstop2 is a monoclonal antibody that binds to the epidermal growth factor receptor (EGFR) and inhibits cell proliferation. This drug has been shown to inhibit tumor growth in vitro, in vivo, and in clinical trials. Pitstop2 blocks the binding of epidermal growth factor to the EGFR, thereby preventing activation of the cells. Pitstop2 also prevents phosphorylation of the protein kinase B/Akt pathway, which is required for cellular proliferation and survival. The drug has been shown to be effective against a number of carcinoma cell lines and has been used to treat patients with advanced solid tumors.

Formula: C₂₀H₁₃BrN₂O₃S₂

Purity: Min. 95%

Molecular weight: 473.4 g/mol

Ref: 3D-HDC87952