CAS 1334509-86-2

(S)-2-(((9H-fluoren-9-yl)Methoxy)carbonylaMino)-3-(1-Methyl-1H-indol-3-yl)propanoic acid

Description:

(S)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3-(1-methyl-1H-indol-3-yl)propanoic acid, with CAS number 1334509-86-2, is a synthetic organic compound characterized by its complex structure, which includes a fluorenyl moiety, a methoxycarbonyl group, and an indole derivative. This compound is typically classified as an amino acid derivative due to the presence of the propanoic acid backbone and an amino group. Its stereochemistry is indicated by the (S) configuration, suggesting specific spatial arrangements that can influence its biological activity and interactions. The fluorenyl group contributes to its hydrophobic characteristics, while the indole ring may impart unique electronic properties. This compound is of interest in medicinal chemistry and drug development, particularly for its potential applications in targeting specific biological pathways. Its solubility, stability, and reactivity can vary based on environmental conditions, making it a subject of study in various chemical and pharmaceutical contexts.

Formula: C₂₇H₂₄N₂O₄

InChI: InChI=1S/C27H24N2O4/c1-29-15-17(18-8-6-7-13-25(18)29)14-24(26(30)31)28-27(32)33-16-23-21-11-4-2-9-19(21)20-10-3-5-12-22(20)23/h2-13,15,23-24H,14,16H2,1H3,(H,28,32)(H,30,31)/t24-/m0/s1

InChI key: GDPXIUSEXJJUGT-DEOSSOPVSA-N

SMILES: CN1C=C(C2=CC=CC=C21)C[C@@H](C(=O)O)NC(=O)OCC3C4=CC=CC=C4C5=CC=CC=C35

Synonyms:

• Fmoc-Trp(1-Me)-OH
• Fmoc-L-Trp(Me)-OH

Fmoc-Trp(Me)-OH

CAS: 1334509-86-2

Fmoc-Trp(Me) was employed in the Fmoc-SPPS of compstatin analogs.

Formula: C₂₇H₂₄N₂O₄

Purity: 99.5%

Color and Shape: Light Yellow

Molecular weight: 440.5

Ref: 01-4052226

(S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(1-methyl-1H-indol-3-yl)-propionicacid

CAS: 1334509-86-2

Formula: C₂₇H₂₄N₂O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 440.4905

Ref: IN-DA009Z1Z

(S)-2-(((9H-FLUOREN-9-YL)METHOXY)CARBONYLAMINO)-3-(1-METHYL-1H-INDOL-3-YL)PROPANOIC ACID

CAS: 1334509-86-2

Purity: 97%

Molecular weight: 440.4989929

Ref: 10-F792377

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-1-methyl-L-tryptophan-d3

Controlled Product

CAS: 1334509-86-2

Formula: C₂₇D₃H₂₁N₂O₄

Color and Shape: Neat

Molecular weight: 443.509

Ref: TR-F472527

Fmoc-Trp(Me)-OH

Controlled Product

CAS: 1334509-86-2

Fmoc-Trp(Me)-OH is a peptide that has been synthesized as an inhibitor of the enzyme cytochrome P450, which is involved in the metabolism of drugs. Fmoc-Trp(Me)-OH inhibits the activity of cytochrome P450 by binding to its active site and preventing access to substrates. The affinity and conformation of Fmoc-Trp(Me)-OH are optimized for optimal inhibition of cytochrome P450. Half-life values have been determined from a study using rats, which showed that Fmoc-Trp(Me)-OH had a half life of about 8 hours. Hydrophobic interactions between Fmoc-Trp(Me)-OH and the active site of cytochrome P450 are responsible for its inhibitory potency.

Formula: C₂₇H₂₄N₂O₄

Purity: Min. 95%

Color and Shape: Off-White Powder

Molecular weight: 440.49 g/mol

Ref: 3D-FF111359