CAS 133550-49-9

TYRPHOSTIN AG 528

Description:

Tyrphostin AG 528, with the CAS number 133550-49-9, is a synthetic compound known for its role as a selective inhibitor of receptor tyrosine kinases, particularly the epidermal growth factor receptor (EGFR). This compound is characterized by its ability to interfere with cellular signaling pathways that are crucial for cell proliferation and survival, making it a subject of interest in cancer research. Tyrphostin AG 528 exhibits a relatively low molecular weight and is typically used in biochemical studies to explore the mechanisms of cancer cell growth and the potential for therapeutic interventions. Its structure includes functional groups that contribute to its inhibitory activity, and it is often utilized in laboratory settings to assess the effects of tyrosine kinase inhibition on various cellular processes. As with many chemical substances, safety and handling precautions are essential when working with Tyrphostin AG 528, given its biological activity and potential effects on human health.

Formula: C₁₈H₁₄N₂O₃

Synonyms:

• N-(3μ,4μ-Dihydroxybenzylidenecyanoacetyl)indoline, Tyrphostin B66

Tyrphostin AG528

CAS: 133550-49-9

Formula: C₁₈H₁₄N₂O₃

Purity: >97.0%(HPLC)

Color and Shape: Light yellow to Amber to Dark green powder to crystal

Molecular weight: 306.32

Ref: 3B-T3504

AG-528

CAS: 133550-49-9

Formula: C₁₈H₁₄N₂O₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 306.3154

Ref: IN-DA009ZWA

Tyrphostin AG 528

CAS: 133550-49-9

Tyrphostin AG 528

Purity: ≥98%

Molecular weight: 306.32g/mol

Ref: 54-BUP06125

Tyrphostin AG 528

CAS: 133550-49-9

Formula: C₁₈H₁₄N₂O₃

Molecular weight: 306.32

Ref: 7W-GK3156

Tyrphostin AG 528

CAS: 133550-49-9

Tyrphostin AG 528 (Tyrphostin B66) is an inhibitor of EGFR (IC50: 4.9 μM) and ErbB2 (IC50: 2.1 μM).

Formula: C₁₈H₁₄N₂O₃

Purity: 99.64%

Color and Shape: Solid

Molecular weight: 306.32

Ref: TM-T4528