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CAS 133550-49-9

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TYRPHOSTIN AG 528

Description:
Tyrphostin AG 528, with the CAS number 133550-49-9, is a synthetic compound known for its role as a selective inhibitor of receptor tyrosine kinases, particularly the epidermal growth factor receptor (EGFR). This compound is characterized by its ability to interfere with cellular signaling pathways that are crucial for cell proliferation and survival, making it a subject of interest in cancer research. Tyrphostin AG 528 exhibits a relatively low molecular weight and is typically used in biochemical studies to explore the mechanisms of cancer cell growth and the potential for therapeutic interventions. Its structure includes functional groups that contribute to its inhibitory activity, and it is often utilized in laboratory settings to assess the effects of tyrosine kinase inhibition on various cellular processes. As with many chemical substances, safety and handling precautions are essential when working with Tyrphostin AG 528, given its biological activity and potential effects on human health.
Formula:C18H14N2O3
InChI:InChI=1S/C18H14N2O3/c19-11-14(9-12-5-6-16(21)17(22)10-12)18(23)20-8-7-13-3-1-2-4-15(13)20/h1-6,9-10,21-22H,7-8H2/b14-9+
InChI key:MYKCTDWWIWGLHW-NTEUORMPSA-N
SMILES:C1CN(C2=CC=CC=C21)C(=O)/C(=C/C3=CC(=C(C=C3)O)O)/C#N
Synonyms:
  • N-(3μ,4μ-Dihydroxybenzylidenecyanoacetyl)indoline, Tyrphostin B66
Found 6 products.