CAS 1338190-14-9

F44-A13

Synonyms:

• F44-A13

F44-A13

CAS: 1338190-14-9

F44-A13 is an orally active, highly selective farnesoid X receptor (FXR) antagonist with an IC50 value of 1.1 μM. It optimizes cholesterol metabolism and reduces activity by inducing CYP7A1 expression, lowering cholesterol, triglycerides, and low-density lipoprotein cholesterol (LDL-C) levels in mouse models. F44-A13 is applicable for studying metabolic diseases associated with lipid disorders [1].

Formula: C₂₈H₄₀N₄O₅S

Molecular weight: 544.71

Ref: TM-T86396