CAS 133845-63-3

Formula: C19H18N2O

InChI: InChI=1S/C19H18N2O/c1-2-10-20-13-17-11-16-12-18(8-9-19(16)21-17)22-14-15-6-4-3-5-7-15/h1,3-9,11-12,20-21H,10,13-14H2

InChI key: YFPNAYXYKXAKJC-UHFFFAOYSA-N

SMILES: C#CCNCC1=CC2=C(N1)C=CC(=C2)OCC3=CC=CC=C3

PF-9601N

CAS: 133845-63-3

PF-9601N

Formula: C₁₉H₁₈N₂O

Purity: 98%

Molecular weight: 290.36

Ref: 54-BUP10824

PF9601N

CAS: 133845-63-3

Formula: C₁₉H₁₈N₂O

Purity: 98%

Color and Shape: Solid

Molecular weight: 290.3590

Ref: IN-DA00A18U

PF-9601N

CAS: 133845-63-3

PF-9601N: potent, selective MAO-BI with neuroprotection in PD models.

Formula: C₁₉H₁₈N₂O

Purity: 98.29%

Color and Shape: Solid

Molecular weight: 290.359

Ref: TM-T8849

PF9601N

CAS: 133845-63-3

PF9601N is a selective inhibitor of the enzyme dopamine-beta-hydroxylase (DBH). DBH is a rate-limiting enzyme in the synthesis of dopamine, and PF9601N has been shown to provide neuroprotection against neuronal death. PF9601N binds reversibly to the active site of DBH and inhibits amine oxidation, thereby inhibiting the production of norepinephrine and epinephrine. The basic structure of PF9601N is similar to that of reserpine, which was used for decades as an antihypertensive drug. The in vivo model for PF9601N is rat striatal cells treated with 6-hydroxydopamine, which induces cell death by apoptosis. In response to this treatment, cells treated with PF9601N showed significantly less neuronal death than those not treated with the compound.

Formula: C₁₉H₁₈N₂O

Purity: Min. 95%

Molecular weight: 290.36 g/mol

Ref: 3D-IFA84563