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CAS 133972-52-8

:

BIG ENDOTHELIN-1 (1-31) (HUMAN, BOVINE)

Description:
Big Endothelin-1 (1-31) is a precursor peptide of the endothelin family, specifically derived from the human and bovine sources. It is a 31-amino acid peptide that plays a crucial role in various physiological processes, particularly in vasoconstriction and blood pressure regulation. Endothelins are known for their potent vasoconstrictive properties and are involved in the pathophysiology of several cardiovascular diseases. The peptide is synthesized in endothelial cells and is released into the bloodstream, where it exerts its effects on vascular smooth muscle cells. Big Endothelin-1 is biologically inactive until it is cleaved by specific enzymes to produce the active forms, endothelin-1, endothelin-2, and endothelin-3. Its structure includes a characteristic disulfide bond that is essential for its stability and biological activity. The CAS number 133972-52-8 uniquely identifies this peptide in chemical databases, facilitating research and applications in pharmacology and biochemistry. Overall, Big Endothelin-1 is significant in understanding vascular biology and developing therapeutic strategies for cardiovascular disorders.
Formula:C162H236N38O47S5
Synonyms:
  • Big Et-1 (1-31) (Human, Bovine)
  • Big Et-1 (1-31) (Human, Bovine) Trifluoroacetate Salt
  • Big Endothelin-1 (1-31) (Human, Bovine) Trifluoroacetate Salt
  • Endothelin-1 (1-31) (Human)
  • Cys-Ser-Cys-Ser-Ser-Leu-Met-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp-Val-Asn-Thr-Pro-Glu-His-Val-Val-Pro-Tyr
  • H-Cys-Ser-Cys-Ser-Ser-Leu-Met-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp-Val-Asn-Thr-Pro-Glu-His-Val-Val-Pro-Tyr-Oh
  • Endothelin 1 (swine), 21a-L-valine-21b-L-asparagine-21c-L-threonine-21d-L-proline-21e-L-glutamic acid-21f-L-histidine-21g-L-valine-21h-L-valine-21i-L-proline-21j-L-tyrosine-
  • BIG ENDOTHELIN-1 (1-31) (HUMAN, BOVINE)
  • Big Endothelin-1 (1-31) (human, bovine) trifluoroacetate salt H-Cys-Ser-Cys-Ser-Ser-Leu-Met-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp-Val-Asn-Thr-Pro-Glu-His-Val-Val-Pro-Tyr-OH trifluoroacetate salt (Disulfide bonds between Cys1 and Cys15/Cys3 and Cys11)
  • Big Endothelin-1 (1-31) (huMan, bovine)
  • 1-31-Human big endothelin 1
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Found 2 products.
  • Endothelin-1 (1-31) (Human)
    Biosynth
    + Info

    Endothelin-1 (1-31) (Human)

    CAS:
    <p>Endothelin-1 is a peptide that acts as a vasoconstrictor and plays an important role in the regulation of blood pressure. Endothelin-1 is also an endogenous ligand for two G protein-coupled receptors, ETA and ETB. Interesting Endothelin-1 is the most abundant isoform and is expressed in endothelial cells of every blood vessel. It exerts its vasoconstrictor effects through binding to ETA receptors located on the smooth muscle. This product has disulfide bonds between Cys1-Cys15 and Cys3-Cys11 and is available as a 0.1mg vial.</p>
    Formula:C162H236N38O47S5
    Purity:Min. 95%
    Molecular weight:3,628.2 g/mol

    Ref: 3D-PED-4360-S

    100µg
    724.00€
  • Big Endothelin-1 (1-31) (human, bovine) trifluoroacetate salt )
    Biosynth
    + Info

    Big Endothelin-1 (1-31) (human, bovine) trifluoroacetate salt )

    CAS:
    <p>Please enquire for more information about Big Endothelin-1 (1-31) (human, bovine) trifluoroacetate salt ) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>
    Formula:C162H236N38O47S5
    Purity:Min. 95%
    Molecular weight:3,628.17 g/mol

    Ref: 3D-FB109624

    100µg
    863.00€
    250µg
    1,355.00€
    500µg
    2,276.00€