CAS 13433-09-5

L-Aspartyl-L-phenylalanine

Description:

L-Aspartyl-L-phenylalanine, commonly known as aspartame, is a low-calorie artificial sweetener widely used in food and beverage products. It is a dipeptide composed of the amino acids L-aspartic acid and L-phenylalanine, linked by a peptide bond. This compound is characterized by its sweet taste, which is approximately 200 times sweeter than sucrose, making it an effective sugar substitute. Aspartame is stable under acidic conditions but can degrade when exposed to high temperatures or prolonged storage, which may limit its use in certain cooking applications. It is soluble in water, which enhances its utility in various formulations. However, individuals with phenylketonuria (PKU), a genetic disorder, must avoid aspartame due to its phenylalanine content, as they cannot metabolize this amino acid properly. Aspartame is generally recognized as safe by regulatory agencies when consumed within established acceptable daily intake levels. Its widespread use in diet sodas, sugar-free products, and various food items has made it a significant component of the modern food industry.

Formula: C₁₃H₁₆N₂O₅

InChI: InChI=1S/C13H16N2O5/c14-9(7-11(16)17)12(18)15-10(13(19)20)6-8-4-2-1-3-5-8/h1-5,9-10H,6-7,14H2,(H,15,18)(H,16,17)(H,19,20)/t9-,10-/m0/s1

InChI key: InChIKey=YZQCXOFQZKCETR-UWVGGRQHSA-N

SMILES: C([C@H](NC([C@H](CC(O)=O)N)=O)C(O)=O)C1=CC=CC=C1

Synonyms:

• α-L-Aspartyl-L-phenylalanine
• L-Phenylalanine, N-L-α-aspartyl-
• L-α-Aspartyl-L-phenylalanine
• Succinamic acid, 3-amino-N-(α-carboxyphenethyl)-, stereoisomer
• L-Phenylalanine, L-α-aspartyl-

H-Asp-Phe-OH

CAS: 13433-09-5

Aspartame Impurity B, saponofication product of aspartame.

Formula: C₁₃H₁₆N₂O₅

Purity: ≥ 98%

Color and Shape: White Powder

Molecular weight: 280.28

Ref: 01-4001477

H-Asp-Phe-OH

CAS: 13433-09-5

Formula: C₁₃H₁₆N₂O₅

Purity: 97%

Color and Shape: Solid

Molecular weight: 280.2765

Ref: IN-DA003QU2

Asp-Phe

CAS: 13433-09-5

Molecular weight: 280.28

Ref: 7W-GM9182

Aspartame EP Impurity B

CAS: 13433-09-5

Formula: C₁₃H₁₆N₂O₅

Color and Shape: White To Off-White Solid

Molecular weight: 280.28

Ref: 4Z-A-761

H-ASP-PHE-OH

CAS: 13433-09-5

H-ASP-PHE-OH

Purity: ≥95%

Molecular weight: 280.28g/mol

Ref: 54-BUP06122

L-α-Aspartyl-L-phenylalanine

CAS: 13433-09-5

Formula: C₁₃H₁₆N₂O₅

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 280.28

Ref: 3B-A3489

L-Aspartyl-L-phenylalanine

Controlled Product

CAS: 13433-09-5

Formula: C₁₃H₁₆N₂O₅

Color and Shape: White

Molecular weight: 280.28

Ref: 86-MM0314.02

L-Aspartyl-L-phenylalanine

CAS: 13433-09-5

L-Aspartyl-L-phenylalanine

Formula: C₁₃H₁₆N₂O₅

Purity: By hplc: 99.1% (Typical Value in Batch COA)

Color and Shape: white to beige solid

Molecular weight: 280.28g/mol

Ref: 54-BIBA1040

H-ASP-PHE-OH

CAS: 13433-09-5

H-ASP-PHE-OH (Aspartyl-phenylalanine) is used as pharmaceutical intermediates

Formula: C₁₃H₁₆N₂O₅

Purity: 99.75%

Color and Shape: Solid

Molecular weight: 280.28

Ref: TM-T1701

L-Aspartyl-L-phenylalanine Hydrochloride

Controlled Product

CAS: 13433-09-5

Applications L-Aspartyl-L-phenylalanine is an impurity of Thiamine (T344185). Thiamine Impurity B.
References Aluwihare, L., et al.: Science, 308, 1007 (2005), Koch, B., et al.: Anal. Chem., 79, 1758 (2007), Reemtsma, T., et al.: Environ. Sci. Technol., 42, 1430 (2008),

Formula: C₁₃H₁₆N₂O₅xHCl

Color and Shape: Neat

Molecular weight: 280.28

Ref: TR-A790010

Aspartame EP Impurity B

CAS: 13433-09-5

Formula: C₁₃H₁₆N₂O₅

Molecular weight: 280.28

Ref: ST-EA-CP-A26002

H-Asp-Phe-OH

CAS: 13433-09-5

H-Asp-Phe-OH is a diagnostic agent that contains the amino acid aspartame and a hydroxyl group. It is hydrolyzed in the body to form aspartic acid, phenylalanine, and methanol. The methyl ester of H-Asp-Phe-OH is hydrochloride. This compound has been used to study locomotor activity in mice and rats. Aspartame has also been shown to be an inhibitor of certain enzymes, such as fatty acid synthase, which is associated with human pathogens. The lc-ms/ms method has been used to detect H-Asp-Phe-OH metabolites in human serum samples. In addition, this compound can be used for the diagnosis of diseases such as diabetes mellitus type 2 and Alzheimer’s disease by measuring uptake into cells at enzyme activities.

Formula: C₁₃H₁₆N₂O₅

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 280.28 g/mol

Ref: 3D-FA108005

(S)-3-Amino-4-(((S)-1-carboxy-2-phenylethyl)amino)-4-oxobutanoic acid

CAS: 13433-09-5

Formula: C₁₃H₁₆N₂O₅

Purity: 95%

Color and Shape: Solid, Crystalline Powder

Molecular weight: 280.28

Ref: 10-F435878

L-Aspartyl-L-phenylalanine Trifluoroacetic Acid Salt

Controlled Product

CAS: 13433-09-5

Impurity Aspartame EP Impurity B
Applications L-Aspartyl-L-phenylalanine (Aspartame EP Impurity B) is an impurity of Thiamine (T344185). Thiamine Impurity B.
References Aluwihare, L., et al.: Science, 308, 1007 (2005), Koch, B., et al.: Anal. Chem., 79, 1758 (2007), Reemtsma, T., et al.: Environ. Sci. Technol., 42, 1430 (2008),

Formula: C₁₃H₁₆N₂O₅·x(C₂HF₃O₂)

Color and Shape: Neat

Molecular weight: 280.28 + x(114.02)

Ref: TR-A790008

L-Aspartyl-L-phenylalanine-d5

Controlled Product

CAS: 13433-09-5

Formula: C₁₃D₅H₁₁N₂O₅

Color and Shape: Neat

Molecular weight: 285.307

Ref: TR-A790012