CAS 13433-13-1

α-L-Aspartyl-L-glutamine

Description:

α-L-Aspartyl-L-glutamine, also known as aspartame, is a dipeptide composed of the amino acids aspartic acid and glutamine. It is characterized by its sweet taste, which is approximately 200 times sweeter than sucrose, making it a popular artificial sweetener in food and beverage products. This compound is soluble in water and has a relatively low molecular weight, contributing to its use in various formulations. α-L-Aspartyl-L-glutamine is stable under acidic conditions but can degrade under high temperatures or alkaline environments, which may limit its application in certain cooking processes. Additionally, it is important to note that individuals with phenylketonuria (PKU) must avoid aspartame, as it contains phenylalanine, an amino acid that they cannot metabolize properly. The compound is generally recognized as safe (GRAS) by regulatory agencies when consumed within established daily intake limits. Its use in the food industry has been extensively studied, and it continues to be a subject of research regarding its long-term health effects.

Formula: C₉H₁₅N₃O₆

InChI: InChI=1S/C9H15N3O6/c10-4(3-7(14)15)8(16)12-5(9(17)18)1-2-6(11)13/h4-5H,1-3,10H2,(H2,11,13)(H,12,16)(H,14,15)(H,17,18)/t4-,5-/m0/s1

InChI key: InChIKey=GSMPSRPMQQDRIB-WHFBIAKZSA-N

SMILES: [C@H](NC([C@H](CC(O)=O)N)=O)(CCC(N)=O)C(O)=O

Synonyms:

• 136: PN: US20090175867 SEQID: 137 unclaimed protein
• <span class="text-smallcaps">L</smallcap>-Glutamine, <smallcap>L</span>-α-aspartyl-
• <span class="text-smallcaps">L</smallcap>-Glutamine, N²-<smallcap>L</span>-α-aspartyl-
• <span class="text-smallcaps">L</smallcap>-α-Aspartyl-<smallcap>L</span>-glutamine
• Glutamine, N²-<span class="text-smallcaps">L</smallcap>-α-aspartyl-, <smallcap>L</span>-
• Glutamine, N²-<span class="text-smallcaps">L</span>-α-aspartyl-
• H-Asp-Gln-OH
• α-<span class="text-smallcaps">L</smallcap>-Aspartyl-<smallcap>L</span>-glutamine
• Glutamine, N2-L-α-aspartyl-, L-
• Glutamine, N2-L-α-aspartyl-
• L-Glutamine, L-α-aspartyl-
• L-α-Aspartyl-L-glutamine

H-Asp-Gln-OH

CAS: 13433-13-1

H-Asp-Gln-OH is a hormone that belongs to the group of peptides and proteins. It is secreted by the adrenal glands, pancreas, and gastrointestinal tract. H-Asp-Gln-OH has been shown to exhibit chronic kidney disease related effects in animal studies. The effect of this hormone on the renal system may be due to its ability to cause an increase in blood pressure and decrease in renal blood flow. H-Asp-Gln-OH also has been shown to be involved in sleep regulation, with an increased frequency of occurrence at night time. This hormone is metabolized through a number of metabolic reactions, including oxidation by peroxidases or cytochrome P450 enzymes, reduction by glutathione reductase or cytochrome b5 reductase, or hydrolysis by esterases or glucuronidases. These metabolites are then excreted into the urine as free amino acids, glycosides

Formula: C₉H₁₅N₃O₆

Purity: Min. 95%

Molecular weight: 261.23 g/mol

Ref: 3D-FA107997