CAS 134523-00-5: Atorvastatin

Description: Atorvastatin is a synthetic lipid-lowering agent belonging to the statin class, primarily used to manage hyperlipidemia and reduce the risk of cardiovascular disease. Its mechanism of action involves the inhibition of HMG-CoA reductase, an enzyme critical in the cholesterol biosynthesis pathway, leading to decreased levels of low-density lipoprotein (LDL) cholesterol and total cholesterol in the bloodstream. Atorvastatin is characterized by its molecular formula, which includes carbon, hydrogen, nitrogen, and oxygen atoms, reflecting its complex structure. The compound is typically administered orally and exhibits good bioavailability. It is metabolized primarily in the liver, with a significant portion undergoing first-pass metabolism. Common side effects may include muscle pain, liver enzyme alterations, and gastrointestinal disturbances. Atorvastatin is often prescribed in conjunction with lifestyle modifications, such as diet and exercise, to enhance its efficacy in lowering cholesterol levels. Its therapeutic benefits, alongside potential risks, necessitate careful monitoring by healthcare professionals during treatment.

Formula: C₃₃H₃₅FN₂O₅

InChI: InChI=1S/C33H35FN2O5/c1-21(2)31-30(33(41)35-25-11-7-4-8-12-25)29(22-9-5-3-6-10-22)32(23-13-15-24(34)16-14-23)36(31)18-17-26(37)19-27(38)20-28(39)40/h3-16,21,26-27,37-38H,17-20H2,1-2H3,(H,35,41)(H,39,40)/t26-,27-/m1/s1

InChI key: InChIKey=XUKUURHRXDUEBC-KAYWLYCHSA-N

SMILES: O=C(O)CC(O)CC(O)CCN1C(C=2C=CC(F)=CC2)=C(C=3C=CC=CC3)C(C(=O)NC=4C=CC=CC4)=C1C(C)C

Synonyms:

• (3R,5R)-7-[2-(4-Fluorophenyl)-3-Phenyl-4-(Phenylcarbamoyl)-5-Propan-2-Yl-Pyrrol-1-Yl]-3,5-Dihydroxy-Heptanoic Acid
• (3R,5R)-7-[2-(4-Fluorophenyl)-5-isopropyl-3-phenyl-4-phenylcarbamoylpyrrol-1-yl]-3,5-dihydroxyheptanoic acid
• (3R,5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid
• (3S,5S)-7-[2-(4-Fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoic acid
• (3S,5S)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid
• (βR,δR)-2-(4-Fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid
• (βR,δR)-2-(p-Fluorophenyl)-β,δ-dihydroxy-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrole-1-heptanoic acid
• 1H-Pyrrole-1-Heptanoic Acid
• 1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-, (βR,δR)-
• 1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-, (βR,δR)-rel-
• 1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-, [R-(R*,R*)]-
• 1H-pyrrole-1-heptanoate, 3-benzoyl-5-(4-fluorophenyl)-β,δ-dihydroxy-2-(1-methylethyl)-4-phenyl-, calcium salt, (betaR,deltaR)- (1:1)
• Atavastatin
• Atofast
• Atorcor
• Atorfit 20
• Atorin
• Atoris
• Atorvastatin Acid
• Atorvox
• Atrox
• Cardyl
• Lipilou
• Lipinon
• Statofilm
• calcium bis{(3R,5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoate}
• Atorvastatin

Atorvastatin Calcium Salt Trihydrate

CAS: 134523-00-5134523-03-8 344423-98-9

• Formula: C₆₆H₆₈CaF₂N₄O₁₀·3H₂O
• Purity: >98.0%(HPLC)(N)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 1,209.41

(3R,5R)-7-[2-(4-Fluorophenyl)-5-isopropyl-3-phenyl-4-phenylcarbamoylpyrrol-1-yl]-3,5-dihydroxyheptanoic acid

CAS: 134523-00-5

• Formula: C₃₃H₃₅FN₂O₅
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 558.6398

Atorvastatin

CAS: 134523-00-5

• Formula: C₃₃H₃₅FN₂O₅
• Purity: ≥ 98.5%
• Color and Shape: White to off-white crystalline powder
• Molecular weight: 558.64

(3R,5R)-7-(2-(4-Fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoic acid

CAS: 134523-00-5

• Purity: 98.0%
• Color and Shape: Solid, White powder
• Molecular weight: 558.650024414063

Des-(N-Phenyl)Carbamoyl Atorvastatin Calcium Salt

CAS: 134523-00-52247346-41-2

• Formula: (C₂₆H₂₉FNO₄)•Ca
• Color and Shape: Neat
• Molecular weight: 2(438.52) + (40.08)

Atorvastatin acid

CAS: 134523-00-5

Please enquire for more information about Atorvastatin acid including the price, delivery time and more …

• Formula: C₃₃H₃₅FN₂O₅
• Purity: Min. 98 Area-%
• Color and Shape: White Powder
• Molecular weight: 558.64 g/mol

Atorvastatin

CAS: 134523-00-5

Orally active atorvastatin inhibits HMG-CoA reductase, lowers lipids, hinders SV-SMC cell growth, and can up …

• Formula: C₃₃H₃₅FN₂O₅
• Purity: 99.69%
• Color and Shape: Solid
• Molecular weight: 558.64

3-Fluoro Atorvastatin Sodium Salt-d5

CAS: 134523-00-5

• Formula: C₃₃D₅H₂₉FN₂NaO₅
• Color and Shape: Neat
• Molecular weight: 585.652

3-Fluoro Atorvastatin Sodium Salt

CAS: 134523-00-5

Applications 3-Fluoro Atorvastatin Sodium Salt is an impurity of Atorvastatin (A791750, Ca Salt); a selective, …

• Formula: C₃₃H₃₄FN₂NaO₅
• Color and Shape: Neat
• Molecular weight: 580.62