CAS 134523-03-8

Atorvastatin Calcium

Description:

Atorvastatin Calcium is a pharmaceutical compound primarily used as a lipid-lowering agent to manage hyperlipidemia and reduce the risk of cardiovascular disease. It belongs to the class of drugs known as statins, which function by inhibiting the enzyme HMG-CoA reductase, a key player in cholesterol biosynthesis in the liver. This action leads to a decrease in low-density lipoprotein (LDL) cholesterol and triglycerides while increasing high-density lipoprotein (HDL) cholesterol levels. Atorvastatin is typically administered orally and is well-absorbed in the gastrointestinal tract. Its solubility is influenced by pH, with better solubility in acidic conditions. The compound is characterized by its molecular formula, which reflects its complex structure, and it exists as a calcium salt to enhance its stability and bioavailability. Common side effects may include muscle pain, liver enzyme alterations, and gastrointestinal disturbances. As with all medications, atorvastatin should be used under medical supervision, considering potential interactions with other drugs and individual patient health profiles.

Formula:C₆₆H₆₈Ca₂F₂N₄O₁₀

InChI:InChI=1/2C33H35FN2O5.2Ca.2H/c2*1-21(2)31-30(33(41)35-25-11-7-4-8-12-25)29(22-9-5-3-6-10-22)32(23-13-15-24(34)16-14-23)36(31)18-17-26(37)19-27(38)20-28(39)40;;;;/h2*3-16,21,26-27,37-38H,17-20H2,1-2H3,(H,35,41)(H,39,40);;;;/q;;;+2;;/p-2/t2*26-,27-;;;;/m11..../s1/r2C33H35FN2O5.CaH2.Ca/c2*1-21(2)31-30(33(41)35-25-11-7-4-8-12-25)29(22-9-5-3-6-10-22)32(23-13-15-24(34)16-14-23)36(31)18-17-26(37)19-27(38)20-28(39)40;;/h2*3-16,21,26-27,37-38H,17-20H2,1-2H3,(H,35,41)(H,39,40);1H2;/q;;;+2/p-2/t2*26-,27-;;/m11../s1

InChI key:InChIKey=BWFCZHDTTAYGNN-CNZCJKERSA-N

SMILES:C(NC1=CC=CC=C1)(=O)C=2C(=C(N(CC[C@H](C[C@H](CC(O)=O)O)O)C2C(C)C)C3=CC=C(F)C=C3)C4=CC=CC=C4.[Ca]

Synonyms:

(3R,5R)-7-[2-(4-Fluorophenyl)-5-Isopropyl-3-Phenyl-4-(Pheynylcarbamoyl)Pyrrol-1-yl]-3,5-Dihydroheptanoic Acid,calcium salt
(3R,5R)-7-[2-(4-Fluorophenyl)-5-Isopropyl-3-Phenyl-4-(Pheynylcarbamoyl)Pyrrol-1-yl]-3,5�CDihydroheptanoic Acid,calcium salt
(3R,5R)-7-[2-(4-Fluorophenyl)-5-Isopropyl-3-Phenyl-4-(Pheynylcarbamoyl)Pyrrol-1-yl]-3,5�CDihydroheptanoic Acid,calcium salt(L-4)
(R-(R*,R*))-, Atorvastatin calcium
1H-Pyrrole-1-Heptanoicacid,Beta,Delta-Dihydroxy-2-(4-Fluorophenyl)-5-(1-Methy Calciumsalt(2:1),(R-(R*,R*))-Lethyl)-3-Phenyl-4-((Phenylamino)Carbonyl)
1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-((phenylamino)carbonyl)-calcium salt (2: 1), (R-(R*,R*))-
1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-, calcium salt (2:1), (βR,δR)-
1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-, calcium salt (2:1), [R-(R*,R*)]-
1H-Pyrrole-1-heptanoic acid,beta,delta-dihydroxy-2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-((phenylamino)carbonyl)-calcium salt (2: 1)
Atocor
Atoraz
Atorvastatin Ca
Atorvastatin Calcium Anhydrous
Atorvastatin Calsium
Atorvastatin calcium (USAN)
Atorvastatin calcium salt
Atorvastatin hemicalcium
Atorvastatin hemicalcium salt
Atorvastatincalcuim
Beta,Delta-Dihydroxy-2-(4-Fluorophenyl)-5-(1-Methylethyl)-3-Phenyl-4-((Phenylamino)Carbonyl)-Calcium Salt(2:1)
C08078
Calcium (betaR,deltaR)-2-(p-fluorophenyl)-beta,delta-dihydroxy-5-isopr opyl-3-phenyl-4-(phenylcarbamoyl)pyrrole-1-heptanoate (1:2)
Ci-981
D00887
Delta-Dihydroxy-2-(4-Fluorophenyl)-5-(1-Methylethyl)-3-Phenyl-4-((Phenylamino)Carbonyl)-Betcalci1H-Pyrrole-1-Heptanoicaci
Drg-0321
L-4
Lipibec
Lipitor
Lipitor (TN)
Lorvast
Lowlip
Ls-136974
Pd 134298-38A
Pd134298-38A
Prevencor
Rotacor
Sortis
Storvas
Tahor
Torvast
Ym-548
[R-(R*, R*)]-7-[2-(4-Fluorophenyl)-5-(1-Methylethyl)-3-Phenyl-4-(Phenylaminocarbonyl)-1H-Pyrrol-1-Yl]-3,5-Dihydroxy-Heptanoic Acid Calcium Salt
calcium (3R,5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-p ropan-2-yl-pyrrol-1-yl]-3,5-dihydroxy-heptanoate
Atorvastatin calcium
calciumsalt(2:1),(r-(r*,r*))-lethyl)-3-phenyl-4-((phenylamino)carbonyl)
(3R ,5R )-7-[2-(4-Fluorophenyl)-5-Isopropyl-3-Phenyl-4-(Pheynylcarbamoyl) Pyrrol-1-yl]-3 ,5-Dihydroheptanoic Acid, calcium salt (2:1) Trihydrate
3R ,5R )-7-[2-(4-Fluorophenyl)-5-Isopropyl-3-Phenyl-4-(Pheynylcarbamoyl) Pyrrol-1-yl]-3 ,5 ydroheptanoic Acid, calcium salt (2:1) Trihydrate
1h-pyrrole-1-heptanoicacid,beta,delta-dihydroxy-2-(4-fluorophenyl)-5-(1-methy
Atrovastatin calcium
(bR,dR)-2-(4-Fluorophenyl)-b,d-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid
ATORVASTATINE CADIUM
3S,5S-Atorvastatin
Atorvastatin Calclum
ATORVASTATIN CALCIUM MM(CRM STANDARD)
See more synonyms

Purity (%)

100

Found 15 products.

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Atorvastatin Calcium Salt Trihydrate
CAS:
Formula:C₆₆H₆₈CaF₂N₄O₁₀·3H₂O
Purity:>98.0%(HPLC)(N)
Color and Shape:White to Almost white powder to crystal
Molecular weight:1,209.41
Ref: 3B-A2476
1g
54.00€
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5g
176.00€
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Atorvastatin calcium
CAS:
- 134523-03-8
Atorvastatin calcium
Formula:C₆₆H₆₈CaF₂N₄O₁₀
Purity:95.1%
Color and Shape:White. To. Off-White
Molecular weight:1154.45294
Ref: 47-1267
100mg
242.00€
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1H-Pyrrole-1-heptanoicacid,2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-,calciumsalt(2:1),(βR,δR)-
CAS:
- 134523-03-8
Formula:C₆₆H₆₈CaF₂N₄O₁₀
Purity:97%
Color and Shape:Solid
Molecular weight:1155.3417
Ref: IN-DA00368S
100mg
28.00€
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250mg
34.00€
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1g
89.00€
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Atorvastatin Calcium Salt
CAS:
- 134523-03-8
Formula:C₃₃H₃₄FN₂O₅·5Ca
Color and Shape:White To Off-White Solid
Molecular weight:557.64 0.5*40.08
Ref: 4Z-A-121
5mg
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100mg
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10mg
343.00€
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25mg
436.00€
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50mg
623.00€
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Atorvastatin calcium salt
CAS:
- 134523-03-8
Formula:C₃₃H₃₄FN₂O₅·5Ca·5H₂O
Purity:98.0 - 102.0 % (anhydrous basis)
Color and Shape:White to almost white crystalline powder
Molecular weight:604.69
Ref: 7W-GP5009
250mg
66.00€
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1g
184.00€
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Atorvastatin Calcium
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 134523-03-8
Formula:C₃₃H₃₄FN₂O₅·Ca
Color and Shape:Neat
Molecular weight:1155.34
Ref: 86-MM0400.00
100mg
2,317.00€
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Atorvastatin Calcium
CAS:
- 134523-03-8
Color and Shape:Neat
Ref: 61-FOR0400.00
10mg
518.00€
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Atorvastatin calcium
CAS:
- 134523-03-8
Formula:C₃₃H₃₄FN₂O₅·Ca
Color and Shape:Neat
Molecular weight:1155.34
Ref: 04-C10318000
100mg
286.00€
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Atorvastatin hemicalcium salt (Standard)
CAS:
- 134523-03-8
Atorvastatin hemicalcium salt (Standard) is the standard substance of Atorvastatin hemicalcium salt, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Atorvastatin hemicalcium salt (Atorvastatin Calcium) is an HMG-CoA reductase inhibitor with oral activity. Atorvastatin hemicalcium salt is used to lower cholesterol.
Formula:C₃₃H₃₄FN₂O₅Ca
Color and Shape:Solid
Molecular weight:577.67
Ref: TM-TMSM-0471
100mg
353.00€
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Atorvastatin Impurity 61
CAS:
- 134523-03-8
Formula:C₄₀H₄₇FN₂O₆
Color and Shape:White To Off-White Solid
Molecular weight:670.82
Ref: 4Z-A-12102
5mg
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10mg
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25mg
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50mg
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100mg
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Atorvastatin hemicalcium salt
CAS:
- 134523-03-8
Atorvastatin hemicalcium salt (Atorvastatin Calcium) is an orally HMG-CoA reductase inhibitor that lowers cholesterol. Cost-effective and quality-assured.
Formula:C₃₃H₃₄FN₂O₅Ca
Purity:99.27% - >99.99%
Color and Shape:White Solid
Molecular weight:577.67
Ref: TM-T3116
1mL*10mM (DMSO)
39.00€
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10mg
50.00€
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25mg
55.00€
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50mg
63.00€
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100mg
94.00€
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200mg
155.00€
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500mg
280.00€
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Atorvastatin Calcium
CAS:
- 134523-03-8
Formula:C₃₃H₃₄FN₂O₅(Ca)
Molecular weight:557.6 : 1/2(40.1)
Ref: ST-EA-CP-A32046
10mg
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25mg
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100mg
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Atorvastatin Calcium Salt
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 134523-03-8
Applications A selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglyceinhibitorrides in patients with hypercholesterolemia.
References Zhao Y et al. Medicine (Baltimore). 2017 Feb;96(7):e6104.Wu X et al. Carcinogenesis. 2017 Feb 16Sepehri Z et al. PLoS One. 2017 Feb 13;12(2):e0172404
Formula:C₃₃H₃₄FN₂O₅·Ca
Color and Shape:Neat
Molecular weight:1155.34
Ref: TR-A791750
5mg
94.00€
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50mg
179.00€
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500mg
350.00€
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Atorvastatin calcium salt - Bio-X ™
CAS:
- 134523-03-8
Atorvastatin is an HMG-CoA reductase inhibitor that is used to lower lipid levels and to aid in the management of cardiovascular diseases. Animal studies have demonstrated that this drug has vasculoprotective properties.
Formula:(C₃₃H₃₅FN₂O₅)₂•Ca
Purity:Min. 95%
Color and Shape:Powder
Molecular weight:1,157.36 g/mol
Ref: 3D-BA164226
100mg
186.00€
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Atorvastatin calcium
CAS:
- 134523-03-8
HMG-CoA reductase inhibitor; anti-hypercholesterolemia agent
Formula:C₆₆H₆₈CaF₂N₄O₁₀
Purity:Min. 97 Area-%
Color and Shape:White Powder
Molecular weight:1,155.34 g/mol
Ref: 3D-FA57652
25g
319.00€
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50g
501.00€
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100g
787.00€
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250g
1,470.00€
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500g
2,317.00€
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