CAS 134612-80-9

3-METHOXY-4-HYDROXY-5-NITROBENZYL,4'-METHYLBENZYL KETONE

Description:

3-Methoxy-4-hydroxy-5-nitrobenzyl, 4'-methylbenzyl ketone, identified by its CAS number 134612-80-9, is an organic compound characterized by its complex structure, which includes a methoxy group, a hydroxy group, and a nitro group attached to a benzyl moiety. This compound typically exhibits properties associated with aromatic compounds, such as stability and potential for various chemical reactions, including electrophilic substitutions. The presence of functional groups like methoxy and hydroxy can influence its solubility in polar solvents, while the nitro group may impart unique reactivity and electronic properties. Additionally, the ketone functional group contributes to its potential as a precursor in organic synthesis. This compound may also exhibit biological activity, making it of interest in pharmaceutical research. However, specific physical properties such as melting point, boiling point, and solubility would need to be referenced from experimental data or literature for precise applications and handling guidelines.

Formula: C₁₅H₁₃NO₅

InChI: InChI=1/C15H13NO5/c1-9-3-5-10(6-4-9)14(17)11-7-12(16(19)20)15(18)13(8-11)21-2/h3-8,18H,1-2H3

SMILES: Cc1ccc(cc1)C(=O)c1cc(c(c(c1)OC)O)N(=O)=O

Synonyms:

• 3-O-methyltolcapone
• (4-Hydroxy-3-Methoxy-5-Nitrophenyl)(4-Methylphenyl)Methanone

Tolcapone Related Compound B (4-hydroxy-3-methoxy-4'-methyl-5-nitrobenzophenone)

CAS: 134612-80-9

Halogenated, sulfonated, nitrated or nitrosated derivat

Formula: C₁₅H₁₃NO₅

Color and Shape: Yellow Crystalline Powder

Molecular weight: 287.07937

Ref: 45-1670229

3-METHOXY-4-HYDROXY-5-NITROBENZYL,4'-METHYLBENZYL KETONE

CAS: 134612-80-9

Formula: C₁₅H₁₃NO₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 287.2674

Ref: IN-DA009F47

(4-Hydroxy-3-methoxy-5-nitrophenyl)(p-tolyl)methanone

CAS: 134612-80-9

(4-Hydroxy-3-methoxy-5-nitrophenyl)(p-tolyl)methanone

Formula: C₁₅H₁₃NO₅

Purity: 98%

Molecular weight: 287.27

Ref: 54-OR1061928

3-O-Methyl Tolcapone

CAS: 134612-80-9

Formula: C₁₅H₁₃NO₅

Color and Shape: Yellow Solid

Molecular weight: 287.27

Ref: 4Z-T-154

4-Hydroxy-3-methoxy-4'-methyl-5-nitrobenzophenone

Controlled Product

CAS: 134612-80-9

Formula: C₁₅H₁₃NO₅

Color and Shape: Neat

Molecular weight: 287.27

Ref: 86-MM3329.01

3-O-Methyl tolcapone

Controlled Product

CAS: 134612-80-9

3-O-Methyl tolcapone is a catechol-O-methyltransferase (COMT) inhibitor that is used to treat Parkinson's disease. It has been shown to increase the plasma concentrations of levodopa by about 40% in humans. This drug is also effective for the treatment of Parkinson's disease in animals, and has been shown to be safe for use in humans. 3-O-Methyl tolcapone is given orally as a tablet and it is absorbed from the gastrointestinal tract. The drug binds competitively with COMT, thereby inhibiting its activity. This inhibition leads to increased levels of levodopa and dopamine in the brain, which can improve symptoms of Parkinson's disease.

Formula: C₁₅H₁₃NO₅

Purity: Min. 95%

Color and Shape: Yellow Powder

Molecular weight: 287.27 g/mol

Ref: 3D-FM25570

3-O-Methyltolcapone

CAS: 134612-80-9

(4-Hydroxy-3-methoxy-5-nitrophenyl)(p-tolyl)methanone

Formula: C₁₅H₁₃NO₅

Purity: 98%

Molecular weight: 287.27

Ref: IN-DG258251

(4-Hydroxy-3-methoxy-5-nitrophenyl)(p-tolyl)methanone

CAS: 134612-80-9

Formula: C₁₅H₁₃NO₅

Purity: 95.0%

Molecular weight: 287.271

Ref: 10-F429833

3-O-Methyltolcapone

CAS: 134612-80-9

3-O-Methyltolcapone (Ro 40-7591) is a metabolite of Tolcapone which is a potent COMT inhibitor.

Formula: C₁₅H₁₃NO₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 287.27

Ref: TM-T10119

3-O-Methyl Tolcapone-d4

Controlled Product

CAS: 134612-80-9

Applications Isotope labelled 3-O-Methyl Tolcapone is a metabolite of the catechol-O-Methyl transferase inhibitor Tolcapone (T535250).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Jorga, K. et al.: Br. J. Clin. Pharmacol., 48, 513 (1999); Funaki, T. et al.: J. Pharm. Pharmacol., 46, 571 (1994); Sun, J. et al.: J. Chrom. B Anal. Technol. Biomed. Life Sci., 877, 2557 (2009); Heizmann, P. et al.: J. Chrom. B Biomed. Sci. Appl., 730, 153 (1999);

Formula: C₁₅H₉D₄NO₅

Color and Shape: Neat

Molecular weight: 291.29

Ref: TR-M330892

4-Hydroxy-3-methoxy-4'-methyl-5-nitrobenzophenone

CAS: 134612-80-9

Formula: C₁₅H₁₃NO₅

Color and Shape: Neat

Molecular weight: 287.27

Ref: TR-M330890

Tolcapone Related compound B

CAS: 134612-80-9

Formula: C₁₅H₁₃NO₅

Molecular weight: 287.27

Ref: ST-EA-CP-T164002