CAS 134678-17-4: Lamivudine

Description: Lamivudine is an antiretroviral medication primarily used in the treatment of HIV/AIDS and chronic hepatitis B infection. It belongs to the class of nucleoside reverse transcriptase inhibitors (NRTIs) and functions by inhibiting the reverse transcriptase enzyme, which is crucial for viral replication. The chemical formula of Lamivudine is C8H11N3O3S, and it features a thiophenecarboxamide structure, which contributes to its pharmacological activity. Lamivudine is typically administered orally and is well-absorbed in the gastrointestinal tract, with a favorable safety profile. Common side effects may include headache, fatigue, and gastrointestinal disturbances. It is important to note that Lamivudine is often used in combination with other antiretroviral agents to enhance efficacy and reduce the risk of resistance. The substance is classified as a prescription medication and is included in various treatment guidelines for managing HIV and hepatitis B. Its effectiveness and safety have been well-documented in clinical studies, making it a vital component of antiviral therapy.

Formula: C₈H₁₁N₃O₃S

InChI: InChI=1S/C8H11N3O3S/c9-5-1-2-11(8(13)10-5)6-4-15-7(3-12)14-6/h1-2,6-7,12H,3-4H2,(H2,9,10,13)/t6-,7+/m0/s1

InChI key: InChIKey=JTEGQNOMFQHVDC-NKWVEPMBSA-N

SMILES: O=C1N=C(N)C=CN1C2OC(SC2)CO

Synonyms:

• (-) 2'-Deoxy-3'-thiacytidine
• (-)-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cystosine
• (-)-2¢ -Deoxy-3¢ -Thiacytidine
• (-)-Bch-189
• (-)Ngpb-21
• (2R-cis)-4-Amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone
• (2R-cis)-4-amino-1-
• 1,3-Oxathiolane, 2(1H)-pyrimidinone deriv.
• 2(1H)-Pyrimidinone, 4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-
• 2(1H)-Pyrimidinone,4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-,(2R-cis)-
• 2-Hydroxymethyl-5-(cytosin-1-yl)-1,3-oxathiolane
• 3'-Thia-2',3'-Dideoxcytidine
• 3TC
• 3¢ -Thia-2¢ ,3¢ -Dideoxycytidine
• 4-Amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone
• 4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one
• 4-amino-1-[(2S,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one
• <span class="text-smallcaps">L</span>-SddC
• Epivir
• Epivir HBV
• Gr 109714X
• Gr109714X
• Hepitec
• Heptodin
• Heptovir
• Hiviral
• Lamidine
• Lamivir
• Virolam
• Zeffix
• Zefix
• cis(-)-2-Hydroxymethyl-5-(cytosin-1-yl)-1,3-oxathiolane
• β-<span class="text-smallcaps">L</span>-2′,3′-Dideoxy-3′-thiacytidine
• β-<span class="text-smallcaps">L</span>-3′-Thia-2′,3′-dideoxycytidine
• 3￠-thia-2￠,3￠-dideoxycytidine
• (-)-2￠-deoxy-3￠-thiacytidine

Lamivudine RS

CAS: 134678-17-4

• Formula: C₈H₁₁N₃O₃S
• Molecular weight: 229.2562

Lamivudine for system suitability 1 CRS

CAS: 134678-17-4

• Formula: C₈H₁₁N₃O₃S
• Molecular weight: 229.2562

Lamivudine CRS

CAS: 134678-17-4

• Formula: C₈H₁₁N₃O₃S
• Color and Shape: White. Powder.
• Molecular weight: 229.2562

Lamivudine

CAS: 134678-17-4

• Formula: C₈H₁₁N₃O₃S
• Purity: 99.8%
• Color and Shape: White
• Molecular weight: 229.05211

Lamivudine for system suitability RS

CAS: 134678-17-4

• Formula: C₈H₁₁N₃O₃S
• Molecular weight: 229.2562

Lamivudine impurity standard

CAS: 134678-17-4

• Color and Shape: According To Product Specification Solid

Lamivudine

CAS: 134678-17-4

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

• Formula: C₈H₁₁N₃O₃S
• Color and Shape: White Off-White Crystalline Powder
• Molecular weight: 229.26

4-Amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone

CAS: 134678-17-4

• Formula: C₈H₁₁N₃O₃S
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 229.25624000000008

Lamivudine

CAS: 134678-17-4

• Purity: 99.56%
• Molecular weight: 229.26g/mol

Lamivudine

CAS: 134678-17-4

• Molecular weight: 229.26g/mol

Lamivudine-13C-d2

CAS: 134678-17-4

• Formula: C₇₁₃CH₉D₂N₃O₃S
• Molecular weight: 232.26

Lamivudine

CAS: 134678-17-4

• Formula: C₈H₁₁N₃O₃S
• Purity: 98.0 - 102.0 % (anhydrous, solvent-free basis)
• Color and Shape: White to off-white powder
• Molecular weight: 229.26

Lamivudine-13C-15N2

CAS: 134678-17-4

• Formula: C₇₁₃CH₁₁N₁₅N₂O₃S
• Color and Shape: White To Off-White Solid
• Molecular weight: 232.23

Lamivudine

CAS: 134678-17-4

• Formula: C₈H₁₁N₃O₃S
• Color and Shape: White To Off-White Solid
• Molecular weight: 229.25

Lamivudine

CAS: 134678-17-4

• Formula: C₈H₁₁N₃O₃S
• Color and Shape: Neat
• Molecular weight: 229.26

Lamivudeine

CAS: 134678-17-4

• Formula: C₈H₁₁N₃O₃S
• Color and Shape: Neat
• Molecular weight: 229.26

4-Amino-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one

CAS: 134678-17-4

• Purity: 95.0%
• Color and Shape: Solid, White to very pale yellow powder
• Molecular weight: 229.25

Lamivudine, 98%

CAS: 134678-17-4

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Formula: C₈H₁₁N₃O₃S
• Purity: 98%
• Color and Shape: White to beige, Powder
• Molecular weight: 229.25

Lamivudine

CAS: 134678-17-4

• Formula: C₈H₁₁N₃O₃S
• Purity: >98.0%(T)(HPLC)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 229.25

Lamivudeine 100 µg/mL in Acetonitrile:Water

CAS: 134678-17-4

• Formula: C₈H₁₁N₃O₃S
• Color and Shape: Single Solution
• Molecular weight: 229.26