CAS 134678-17-4

Lamivudine

Description:

Lamivudine is an antiretroviral medication primarily used in the treatment of HIV/AIDS and chronic hepatitis B infection. It belongs to the class of nucleoside reverse transcriptase inhibitors (NRTIs) and functions by inhibiting the reverse transcriptase enzyme, which is crucial for viral replication. The chemical formula of Lamivudine is C8H11N3O3S, and it features a thiophenecarboxamide structure, which contributes to its pharmacological activity. Lamivudine is typically administered orally and is well-absorbed in the gastrointestinal tract, with a favorable safety profile. Common side effects may include headache, fatigue, and gastrointestinal disturbances. It is important to note that Lamivudine is often used in combination with other antiretroviral agents to enhance efficacy and reduce the risk of resistance. The substance is classified as a prescription medication and is included in various treatment guidelines for managing HIV and hepatitis B. Its effectiveness and safety have been well-documented in clinical studies, making it a vital component of antiviral therapy.

Formula: C₈H₁₁N₃O₃S

InChI: InChI=1S/C8H11N3O3S/c9-5-1-2-11(8(13)10-5)6-4-15-7(3-12)14-6/h1-2,6-7,12H,3-4H2,(H2,9,10,13)/t6-,7+/m0/s1

InChI key: InChIKey=JTEGQNOMFQHVDC-NKWVEPMBSA-N

SMILES: O=C1N([C@H]2O[C@@H](CO)SC2)C=CC(N)=N1

Synonyms:

• (-) 2'-Deoxy-3'-thiacytidine
• (-)-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cystosine
• (-)-2¢ -Deoxy-3¢ -Thiacytidine
• (-)-Bch-189
• (-)Ngpb-21
• (2R-cis)-4-Amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone
• (2R-cis)-4-amino-1-
• 1,3-Oxathiolane, 2(1H)-pyrimidinone deriv.
• 2(1H)-Pyrimidinone, 4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-
• 2(1H)-Pyrimidinone,4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-,(2R-cis)-
• 2-Hydroxymethyl-5-(cytosin-1-yl)-1,3-oxathiolane
• 3'-Thia-2',3'-Dideoxcytidine
• 3TC
• 3¢ -Thia-2¢ ,3¢ -Dideoxycytidine
• 4-Amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone
• 4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one
• 4-amino-1-[(2S,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one
• <span class="text-smallcaps">L</span>-SddC
• Epivir
• Epivir HBV
• Gr 109714X
• Gr109714X
• Hepitec
• Heptodin
• Heptovir
• Hiviral
• Lamidine
• Lamivir
• Virolam
• Zeffix
• Zefix
• cis(-)-2-Hydroxymethyl-5-(cytosin-1-yl)-1,3-oxathiolane
• β-<span class="text-smallcaps">L</span>-2′,3′-Dideoxy-3′-thiacytidine
• β-<span class="text-smallcaps">L</span>-3′-Thia-2′,3′-dideoxycytidine
• 3￠-thia-2￠,3￠-dideoxycytidine

Lamivudine

CAS: 134678-17-4

Formula: C₈H₁₁N₃O₃S

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 229.25

Ref: 3B-L0217

Lamivudine

CAS: 134678-17-4

Color and Shape: Neat

Ref: 61-FOR0749.00

LAMIVUDINE FOR SYSTEM SUITABILITY 1 CRS

CAS: 134678-17-4

LAMIVUDINE FOR SYSTEM SUITABILITY 1 CRS

Formula: C₈H₁₁N₃O₃S

Molecular weight: 229.2562

Ref: 41-Y0000518

Lamivudine impurity standard

CAS: 134678-17-4

Lamivudine impurity standard

Color and Shape: According To Product Specification Solid

Ref: 47-857

Lamivudine

CAS: 134678-17-4

Lamivudine

Formula: C₈H₁₁N₃O₃S

Purity: 99.8%

Color and Shape: White

Molecular weight: 229.05211

Ref: 47-802

LAMIVUDINE RS

CAS: 134678-17-4

LAMIVUDINE RS

Formula: C₈H₁₁N₃O₃S

Molecular weight: 229.2562

Ref: 41-ICRS1416

LAMIVUDINE CRS

CAS: 134678-17-4

LAMIVUDINE CRS

Formula: C₈H₁₁N₃O₃S

Color and Shape: White. Powder.

Molecular weight: 229.2562

Ref: 41-Y0000425

LAMIVUDINE FOR SYSTEM SUITABILITY RS

CAS: 134678-17-4

LAMIVUDINE FOR SYSTEM SUITABILITY RS

Formula: C₈H₁₁N₃O₃S

Molecular weight: 229.2562

Ref: 41-ICRS1553

Lamivudine

CAS: 134678-17-4

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

Formula: C₈H₁₁N₃O₃S

Color and Shape: White Off-White Crystalline Powder

Molecular weight: 229.26

Ref: 45-1356836

4-Amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone

CAS: 134678-17-4

Formula: C₈H₁₁N₃O₃S

Purity: 98%

Color and Shape: Solid

Molecular weight: 229.2562

Ref: IN-DA003R7D

Lamivudine

CAS: 134678-17-4

Lamivudine

Purity: ≥98%

Molecular weight: 229.26g/mol

Ref: 54-BUP17053

Lamivudine

CAS: 134678-17-4

Lamivudine

Purity: 98%

Molecular weight: 229.26g/mol

Ref: 54-OR1029140

Lamivudine-13C-d2

CAS: 134678-17-4

Formula: C₇₁₃CH₉D₂N₃O₃S

Molecular weight: 232.26

Ref: 4Z-L-201

Lamivudine

CAS: 134678-17-4

Formula: C₈H₁₁N₃O₃S

Purity: 98.0 - 102.0 % (anhydrous, solvent-free basis)

Color and Shape: White to off-white powder

Molecular weight: 229.26

Ref: 7W-GP6029

Lamivudine-13C-15N2

CAS: 134678-17-4

Formula: C₇₁₃CH₁₁N₁₅N₂O₃S

Color and Shape: White To Off-White Solid

Molecular weight: 232.23

Ref: 4Z-L-202

Lamivudine

CAS: 134678-17-4

Formula: C₈H₁₁N₃O₃S

Color and Shape: White To Off-White Solid

Molecular weight: 229.25

Ref: 4Z-L-203

Lamivudeine

Controlled Product

CAS: 134678-17-4

Formula: C₈H₁₁N₃O₃S

Color and Shape: Neat

Molecular weight: 229.26

Ref: 04-C14591800

Lamivudine

CAS: 134678-17-4

Color and Shape: Neat

Ref: 86-MM0749.00

Lamivudine

CAS: 134678-17-4

Lamivudine (BCH-189) is a reverse transcriptase inhibitor and ZALCITABINE analog in which a sulfur atom replaces the 3' carbon of the pentose ring.

Formula: C₈H₁₁N₃O₃S

Purity: 98.71% - 99.56%

Color and Shape: White Crystalline Powder

Molecular weight: 229.26

Ref: TM-T0682

Lamivudine

Controlled Product

CAS: 134678-17-4

Applications Lamivudine is a potent nucleoside reverse transcriptase inhibitor. Antiviral. Lamivudine has been used for treatment of chronic hepatitis B.
References Morris, D.M., J. Pharm. Biomed. Anal., 12, 255 (1944), Nevens, B.F., et al.: Gastroenterology, 113, 1258 (1997), Perry, C.M., et al.: Drugs, 53, 657 (1977),

Formula: C₈H₁₁N₃O₃S

Color and Shape: White

Molecular weight: 229.26

Ref: TR-L172500