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CAS 13492-01-8

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Tranylcypromine sulfate

Description:
Tranylcypromine sulfate is a chemical compound primarily recognized as a monoamine oxidase inhibitor (MAOI) used in the treatment of depression. It is a derivative of phenethylamine and is characterized by its ability to inhibit the enzyme monoamine oxidase, which is responsible for the breakdown of neurotransmitters such as serotonin, norepinephrine, and dopamine in the brain. This inhibition leads to increased levels of these neurotransmitters, contributing to its antidepressant effects. Tranylcypromine sulfate is typically administered in its sulfate salt form, which enhances its solubility and bioavailability. The compound is known for its potential side effects, including hypertensive crises when consumed with tyramine-rich foods, necessitating dietary restrictions during treatment. Additionally, it may interact with other medications, requiring careful management by healthcare providers. Its chemical structure includes a cyclopropyl group and an amino group, contributing to its pharmacological activity. Overall, Tranylcypromine sulfate is a significant agent in psychopharmacology, particularly for patients who do not respond to other antidepressants.
Formula:C18H24N2O4S
InChI:InChI=1/C9H11N.H2O4S/c10-9-6-8(9)7-4-2-1-3-5-7;1-5(2,3)4/h1-5,8-9H,6,10H2;(H2,1,2,3,4)/t8-,9+;/m0./s1
InChI key:InChIKey=BTHVHSMCHJCPFU-LZPPVNAUNA-N
SMILES:S(=O)(=O)(O)O.N[C@H]1[C@@H](C1)C2=CC=CC=C2
Synonyms:
  • (1R,2S)-2-phenylcyclopropanamine
  • (1R,2S)-2-phenylcyclopropanamine sulfate
  • (2S)-2-phenylcyclopropanamine sulfate
  • Cyclopropanamine, 2-phenyl-, (1R,2S)-rel-, sulfate (2:1)
  • Cyclopropanamine, 2-phenyl-, trans-(±)-, sulfate (2:1)
  • Cyclopropylamine, 2-phenyl-, sulfate (2:1), trans-(±)-
  • Parnate
  • Parnetil
  • Trans-2-Phenylcyclopropylamine Hemisulfate Salt
  • Tranylcypromine Sulfate
  • See more synonyms
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