CAS 1352609-28-9

Formula: C23H18N8

InChI: InChI=1S/C23H18N8/c1-15-4-2-7-19(28-15)23-22(17-8-9-21-26-14-27-31(21)13-17)29-20(30-23)12-25-18-6-3-5-16(10-18)11-24/h2-10,13-14,25H,12H2,1H3,(H,29,30)

InChI key: KEADGKSQIBFYEE-UHFFFAOYSA-N

SMILES: CC1=NC(=CC=C1)C2=C(N=C(N2)CNC3=CC=CC(=C3)C#N)C4=CN5C(=NC=N5)C=C4

EW-7195

CAS: 1352609-28-9

EW-7195

Formula: C₂₃H₁₈N₈

Purity: 99.5%

Molecular weight: 406.44

Ref: 54-BUP07494

EW-7195

CAS: 1352609-28-9

EW-7195 inhibits ALK5/TGFβR1 (>300x selective over p38α) with 4.83 nM IC50, blocking TGF-β1 signaling, EMT, and breast cancer lung metastasis.

Formula: C₂₃H₁₈N₈

Purity: 99.98%

Color and Shape: White Solid

Molecular weight: 406.4426

Ref: TM-T38752

EW-7195

CAS: 1352609-28-9

Ref: IN-DA023KHK