CAS 135459-87-9

Strontium ranelate

Description:

Strontium ranelate is a chemical compound primarily used in the treatment of osteoporosis. It is a strontium salt of ranelic acid, which is a derivative of the amino acid methionine. The compound is characterized by its ability to both stimulate bone formation and inhibit bone resorption, making it unique among osteoporosis treatments. Strontium ranelate is typically administered orally and is known for its relatively good bioavailability. It has a molecular formula that reflects its strontium and ranelate components, contributing to its pharmacological properties. The compound is generally well-tolerated, although it may have some side effects, including gastrointestinal issues. Its mechanism of action involves the modulation of bone metabolism, promoting a balance between bone formation and resorption, which is crucial for maintaining bone density and strength. Due to its specific action on bone tissue, strontium ranelate has been a subject of interest in the field of bone health and osteoporosis management. However, its use may be limited by regulatory guidelines in various countries.

Formula:C₁₂H₁₀N₂O₈S·2Sr

InChI:InChI=1S/C12H10N2O8S.2Sr/c13-2-6-5(1-7(15)16)10(12(21)22)23-11(6)14(3-8(17)18)4-9(19)20;;/h1,3-4H2,(H,15,16)(H,17,18)(H,19,20)(H,21,22);;

InChI key:InChIKey=WJKLKWHUBHCSFS-UHFFFAOYSA-N

SMILES:N(CC(O)=O)(CC(O)=O)C1=C(C#N)C(CC(O)=O)=C(C(O)=O)S1.[Sr]

Synonyms:

3-Thiopheneacetic acid, 5-[bis(carboxymethyl)amino]-2-carboxy-4-cyano-, strontium salt (1:2)
5-[Bis(Carboxymethyl)Amino]-3-(Carboxymethyl)-4-Cyanothiophene-2-Carboxylic Acid
5-[Bis(carboxymethyl)amino]-2-carboxy-4-cyano-3-thiopheneacetic acid strontium salt
5-[Bis(carboxymethyl)amino]-2-carboxy-4-cyano-3-thiopheneacetic acid strontium salt (1:2)
Bivalos
Distrontium renelate
Osseor
Protelos
Protos
Ranelate Strontium
S 12911
S 12911-2
Strometta
Stroncium Ranelate
Strontium 5-[Bis(Carboxylatomethyl)Amino]-3-(Carboxylatomethyl)-4-Cyanothiophene-2-Carboxylate Hydrate (2:1:7)
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