CAS 1359993-59-1

Telratolimod

Description:

Telratolimod, also known by its development code, is an investigational immunomodulatory agent primarily studied for its potential therapeutic applications in oncology and infectious diseases. It is a synthetic compound that acts as a toll-like receptor (TLR) agonist, specifically targeting TLR-7. This mechanism of action is significant as it enhances the immune response by stimulating the production of cytokines and activating various immune cells, including dendritic cells and T cells. Telratolimod is designed to promote a robust antitumor immune response and has been evaluated in clinical trials for its efficacy in combination with other therapies. Its safety profile is still under investigation, but like many immunomodulators, it may be associated with immune-related adverse effects. The compound's pharmacokinetics, including absorption, distribution, metabolism, and excretion, are critical for understanding its therapeutic potential and optimizing its use in clinical settings. Overall, telratolimod represents a promising avenue in the field of immunotherapy, with ongoing research aimed at elucidating its full capabilities and applications.

Formula: C₃₆H₅₉N₅O₂

Synonyms:

• Telratolimod
• Octadecanamide, N-[4-[(4-amino-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl)oxy]butyl]-

TELRATOLIMOD

CAS: 1359993-59-1

Formula: C₃₆H₅₉N₅O₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 593.8860

Ref: IN-DA01FNFI

Telratolimod

CAS: 1359993-59-1

Telratolimod

Purity: ≥98%

Molecular weight: 593.89g/mol

Ref: 54-BUP05327

N-(4-{[4-Amino-2-Butyl-1H-Imidazo[4,5-C]Quinolin-1-Yl]Oxy}Butyl)Octadecanamide

CAS: 1359993-59-1

N-(4-{[4-Amino-2-Butyl-1H-Imidazo[4,5-C]Quinolin-1-Yl]Oxy}Butyl)Octadecanamide

Purity: 98%

Molecular weight: 593.89g/mol

Ref: 54-OR1024317

Telratolimod

CAS: 1359993-59-1

Telratolimod (MEDI9197) is a toll-like receptors 7/8 agonist. It has an antitumor activity.

Formula: C₃₆H₅₉N₅O₂

Purity: 98.61%

Color and Shape: Solid

Molecular weight: 593.89

Ref: TM-T17032

Telratolimod

CAS: 1359993-59-1

Telratolimod, also known as 3M-052, is a lass of vaccine adjuvant that activates TLR7 and 8. It is a lipid-modified derivative of resiquimod (R848) featuring an 18-carbon fatty acyl chain that increases hydrophobicity, enhances retention at immune activation sites, and limits systemic diffusion. This lipidation also facilitates incorporation into delivery platforms such as emulsions and liposomes.As a vaccine adjuvant, 3M-052 has demonstrated potent and durable antibody and T-cell responses in HIV vaccine formulations when combined with PLGA nanoparticles or alum.

Formula: C₃₆H₅₉N₅O₂

Purity: Min. 95%

Molecular weight: 593.9 g/mol

Ref: 3D-JEC99359