CAS 1361504-77-9

Formula: C20H22BrCl2N3

InChI: InChI=1S/C20H20BrN3.2ClH/c1-23-10-12-24(13-11-23)18-8-6-16(7-9-18)14-17(15-22)19-4-2-3-5-20(19)21;;/h2-9,14H,10-13H2,1H3;2*1H/b17-14+;;

InChI key: SABUORLIDVBCPI-WTLOABTRSA-N

SMILES: CN1CCN(CC1)C2=CC=C(C=C2)/C=C(\C#N)/C3=CC=CC=C3Br.Cl.Cl

DG172 dihydrochloride

CAS: 1361504-77-9

DG172 dihydrochloride

Formula: C₂₀H₂₂BrCl₂N₃

Purity: ≥98%

Molecular weight: 455.2

Ref: 54-BUP02130

(Z)-2-(2-Bromophenyl)-3-(4-(4-methylpiperazin-1-yl)phenyl)acrylonitrile dihydrochloride

CAS: 1361504-77-9

Formula: C₂₀H₂₂BrCl₂N₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 455.2188

Ref: IN-DA009CMB

DG172 dihydrochloride

CAS: 1361504-77-9

DG172 dihydrochloride (DG-172 dihydrochloride) is an antagonist of PPARβ/δ(IC50 : 27 nM).

Formula: C₂₀H₂₂BrCl₂N₃

Purity: 99.87%

Color and Shape: White Solid

Molecular weight: 455.2

Ref: TM-T7821

DG 172 hydrochloride

CAS: 1361504-77-9

Potent inverse agonist of peroxisome proliferator-activated receptor PPARβ and PPARδ with IC50 value of 27 nM. In mouse myoblasts, DG 172 enhanced recruitment of transcriptional corepressor and down-regulated transcription of PPARβ/δ target gene Angptl4. DG 172 also possess a PPARβ/δ-independent activity on bone marrow cells and promotes dendritic cell differentiation.

Formula: C₂₀H₂₀BrN₃•HCl

Purity: Min. 95%

Color and Shape: Solid

Molecular weight: 418.76 g/mol

Ref: 3D-BD162804