CAS 1362154-70-8

GNE 617

Description:

GNE 617, identified by its CAS number 1362154-70-8, is a chemical compound that belongs to a class of molecules known for their potential therapeutic applications, particularly in the field of oncology. It is characterized by its specific molecular structure, which includes various functional groups that contribute to its biological activity. GNE 617 is primarily recognized for its role as a selective inhibitor of certain kinases, which are enzymes that play crucial roles in cell signaling pathways. This inhibition can lead to the modulation of cellular processes such as proliferation and survival, making it a candidate for cancer treatment. The compound's solubility, stability, and pharmacokinetic properties are essential for its efficacy and safety in clinical settings. Additionally, ongoing research may explore its interactions with other biological molecules and its potential side effects. As with many investigational drugs, comprehensive studies are necessary to fully understand its characteristics and therapeutic potential.

Formula: C₂₁H₁₅F₂N₃O₃S

InChI: InChI=1S/C21H15F2N3O3S/c22-16-9-17(23)11-19(10-16)30(28,29)18-4-1-14(2-5-18)12-25-21(27)15-3-6-20-24-7-8-26(20)13-15/h1-11,13H,12H2,(H,25,27)

InChI key: XRDVXQQZLHVEQZ-UHFFFAOYSA-N

SMILES: C1=CC(=CC=C1CNC(=O)C2=CN3C=CN=C3C=C2)S(=O)(=O)C4=CC(=CC(=C4)F)F

Synonyms:

• GNE617
• GNE617;GNE 617
• N-[[4-[(3,5-Difluorophenyl)sulfonyl]phenyl]methyl]imidazo[1,2-a]pyridine-6-carboxamide
• N-(4-((3,5-difluorophenyl)sulfonyl)benzyl)imidazo[1,2-a]pyridine-6-carboxamide
• GNE-617 (CAS 1362154-70-8)
• GNE 617
• CS-1587
• GNE-617
• Imidazo[1,2-a]pyridine-6-carboxamide, N-[[4-[(3,5-difluorophenyl)sulfonyl]phenyl]methyl]-

GNE-617

CAS: 1362154-70-8

GNE-617

Formula: C₂₁H₁₅F₂N₃O₃S

Purity: 99.5%

Molecular weight: 427.42

Ref: 54-BUP09599

GNE 617

CAS: 1362154-70-8

Formula: C₂₁H₁₅F₂N₃O₃S

Purity: 98%

Color and Shape: Solid

Molecular weight: 427.4239

Ref: IN-DA009CBT

GNE 617

CAS: 1362154-70-8

Formula: C₂₁H₁₅F₂N₃O₃S

Molecular weight: 427.43

Ref: 4Z-L-182002

GNE-617

CAS: 1362154-70-8

GNE-617, a specific NAMPT inhibitor(IC50=5 nM), shows potency in xenograft models of cancer.

Formula: C₂₁H₁₅F₂N₃O₃S

Purity: 99.38% - 99.71%

Color and Shape: White Solid

Molecular weight: 427.424

Ref: TM-T4335

GNE-617

CAS: 1362154-70-8

N-(4-((3,5-Difluorophenyl)sulfonyl)benzyl)imidazo[1,2-a]pyridine-6-carboxamide

Formula: C₂₁H₁₅F₂N₃O₃S

Purity: 98%

Molecular weight: 427.42

Ref: IN-DG630184

GNE-617

CAS: 1362154-70-8

GNE-617 is a protein that inhibits the binding of a wide range of pharmacological agents to their receptor sites. It has been shown to be active in vitro using a variety of methods, including radioligand binding and immunoassays. GNE-617 has shown a number of pharmacokinetic properties, including high bioavailability. Autophagy is an energy-generating process that involves the degradation of cellular components in response to starvation or other stresses. GNE-617 has been shown to inhibit autophagy in vitro by inhibiting the formation of autophagosomes and lysosomes. This drug also binds to pluripotent cells, which can be used for cell differentiation studies and for investigating the effects on cancerous growths such as carcinomas.

Formula: C₂₁H₁₅F₂N₃O₃S

Purity: Min. 95%

Molecular weight: 427.42 g/mol

Ref: 3D-MEC15470