CAS 136236-51-6

Rasagiline

Description:

Rasagiline is a selective, irreversible monoamine oxidase B (MAO-B) inhibitor primarily used in the treatment of Parkinson's disease. It is characterized by its ability to increase the levels of dopamine in the brain, thereby alleviating symptoms associated with dopamine deficiency. Rasagiline is typically administered orally and is known for its neuroprotective properties, which may contribute to its therapeutic effects. The substance has a molecular formula that reflects its complex structure, and it is often presented as a white to off-white crystalline powder. Its pharmacokinetics indicate that it has a relatively long half-life, allowing for once-daily dosing. Additionally, rasagiline has a favorable safety profile, with common side effects including headache, nausea, and dizziness. It is important to note that rasagiline should be used cautiously in combination with other medications that affect serotonin levels due to the risk of serotonin syndrome. Overall, rasagiline represents a significant advancement in the management of Parkinson's disease, offering symptomatic relief and potential disease-modifying effects.

Formula: C₁₂H₁₃N

InChI: InChI=1S/C12H13N/c1-2-9-13-12-8-7-10-5-3-4-6-11(10)12/h1,3-6,12-13H,7-9H2/t12-/m1/s1

InChI key: InChIKey=RUOKEQAAGRXIBM-GFCCVEGCSA-N

SMILES: N(CC#C)[C@H]1C=2C(CC1)=CC=CC2

Synonyms:

• (1R)-2,3-Dihydro-N-2-propyn-1-yl-1H-inden-1-amine
• (1R)-N-Prop-2-ynyl-2,3-dihydro-1H-inden-1-amine
• (1R)-N-prop-2-yn-1-yl-2,3-dihydro-1H-inden-1-amine
• (R)-(+)-Rasagiline
• (R)-2,3-Dihydro-N-2-Propynyl-1H-Inden-1-Amine
• (R)-N-(2-Propynyl)-2,3-dihydroinden-1-amine
• (R)-N-(Prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-amine
• (R)-N-2-Propynyl-1-indanamine
• 1H-Inden-1-amine, 2,3-dihydro-N-2-propyn-1-yl-, (1R)-
• 1H-Inden-1-amine, 2,3-dihydro-N-2-propynyl-, (1R)-
• 1H-Inden-1-amine, 2,3-dihydro-N-2-propynyl-, (R)-
• Azilect
• R-(+)-N-Propargyl-1-aminoindan
• Rasagiline -13C3

Rasagiline

CAS: 136236-51-6

Formula: C₁₂H₁₃N

Purity: 98%

Color and Shape: Solid

Molecular weight: 171.2383

Ref: IN-DA003CBF

Rasagiline

CAS: 136236-51-6

Rasagiline

Purity: ≥98%

Molecular weight: 171.24g/mol

Ref: 54-BUP15749

Rasagiline

CAS: 136236-51-6

Rasagiline (AGN1135) is an inhibitor of monamine oxidase used as adjunctive therapy in combination with levodopa and carbidopa in the management of Parkinsons

Formula: C₁₂H₁₃N

Purity: 98% - 99.87%

Color and Shape: Solid

Molecular weight: 171.24

Ref: TM-T1119

Rasagiline

CAS: 136236-51-6

Formula: C₁₃H₁₇NO₃S

Molecular weight: 267.34

Ref: 7W-GP5365

Rasagiline

CAS: 136236-51-6

Formula: C₁₂H₁₃N

Molecular weight: 171.24

Ref: ST-EA-CP-R10000

Rasagiline

Controlled Product

CAS: 136236-51-6

Stability Light Sensitive
Applications Rasagiline, is a selective and irreversible propargylamine inhibitor of monoamine oxidase which has been used to increase the availability of dopamine at striatal receptors as a method to treat Parkinson’s disease.
References Youdim, M.B.H., et al.: Br. J. Pharmacol., 132, 500 (2001); Finberg, J.P., Rambam Maimonides Med. J., 1 (2010)

Formula: C₁₂H₁₃N

Color and Shape: Neat

Molecular weight: 171.24

Ref: TR-R126030

(R)-N-(2-Propynyl)-2,3-dihydroinden-1-amine

CAS: 136236-51-6

Formula: C₁₂H₁₃N

Purity: 95%

Color and Shape: Solid

Molecular weight: 171.243

Ref: 10-F078410

(1R)-N-prop-2-ynylindan-1-amine

CAS: 136236-51-6

(1R)-N-prop-2-ynylindan-1-amine

Purity: 95%

Molecular weight: 171.24g/mol

Ref: 54-OR953478