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CAS 136236-51-6

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Rasagiline

Description:
Rasagiline is a selective, irreversible monoamine oxidase B (MAO-B) inhibitor primarily used in the treatment of Parkinson's disease. It is characterized by its ability to increase the levels of dopamine in the brain, thereby alleviating symptoms associated with dopamine deficiency. Rasagiline is typically administered orally and is known for its neuroprotective properties, which may contribute to its therapeutic effects. The substance has a molecular formula that reflects its complex structure, and it is often presented as a white to off-white crystalline powder. Its pharmacokinetics indicate that it has a relatively long half-life, allowing for once-daily dosing. Additionally, rasagiline has a favorable safety profile, with common side effects including headache, nausea, and dizziness. It is important to note that rasagiline should be used cautiously in combination with other medications that affect serotonin levels due to the risk of serotonin syndrome. Overall, rasagiline represents a significant advancement in the management of Parkinson's disease, offering symptomatic relief and potential disease-modifying effects.
Formula:C12H13N
InChI:InChI=1S/C12H13N/c1-2-9-13-12-8-7-10-5-3-4-6-11(10)12/h1,3-6,12-13H,7-9H2/t12-/m1/s1
InChI key:InChIKey=RUOKEQAAGRXIBM-GFCCVEGCSA-N
SMILES:N(CC#C)[C@H]1C=2C(CC1)=CC=CC2
Synonyms:
  • (1R)-2,3-Dihydro-N-2-propyn-1-yl-1H-inden-1-amine
  • (1R)-N-Prop-2-ynyl-2,3-dihydro-1H-inden-1-amine
  • (1R)-N-prop-2-yn-1-yl-2,3-dihydro-1H-inden-1-amine
  • (R)-(+)-Rasagiline
  • (R)-2,3-Dihydro-N-2-Propynyl-1H-Inden-1-Amine
  • (R)-N-(2-Propynyl)-2,3-dihydroinden-1-amine
  • (R)-N-(Prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-amine
  • (R)-N-2-Propynyl-1-indanamine
  • 1H-Inden-1-amine, 2,3-dihydro-N-2-propyn-1-yl-, (1R)-
  • 1H-Inden-1-amine, 2,3-dihydro-N-2-propynyl-, (1R)-
  • See more synonyms
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