CAS 136632-28-5
:trehalose-6-phosphate dipotassium
Description:
Trehalose-6-phosphate dipotassium is a phosphorylated disaccharide derivative, specifically a dipotassium salt of trehalose-6-phosphate. It is characterized by its role as a key intermediate in carbohydrate metabolism, particularly in the trehalose biosynthetic pathway. This compound is known for its stability and solubility in water, making it suitable for various biochemical applications. Trehalose itself is a non-reducing sugar composed of two glucose units, and its phosphate derivative plays a crucial role in cellular energy regulation and stress response mechanisms. The dipotassium form enhances its solubility and bioavailability, which is beneficial in research and potential therapeutic applications. Additionally, trehalose-6-phosphate is involved in signaling pathways that regulate glucose homeostasis and can influence cellular processes such as growth and development. Its unique properties make it a subject of interest in studies related to metabolism, plant biology, and potential applications in food science and medicine.
Formula:C12H23KO14P
InChI:InChI=1/C12H23O14P.K/c13-1-3-5(14)7(16)9(18)11(24-3)26-12-10(19)8(17)6(15)4(25-12)2-23-27(20,21)22;/h3-19H,1-2H2,(H2,20,21,22);/t3-,4-,5-,6-,7+,8+,9-,10-,11-,12-;/m1./s1
InChI key:YKCUKYNZTFYPHM-PVXXTIHASA-L
SMILES:C([C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)COP(=O)([O-])[O-])O)O)O)O)O)O)O.[K+].[K+]
Synonyms:- α-D-glucopyranoside, α-D-glucopyranosyl, 6-(dihydrogen phosphate), monopotassium salt
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Trehalose 6-phosphate dipotassium salt
CAS:Trehalose 6-phosphate dipotassium saltFormula:C12H21K2O14PPurity:≥95%Molecular weight:498.46Trehalose 6-phosphate dipotassium salt
CAS:Formula:C12H21O14PK2Purity:≥ 95.0%Color and Shape:White to off-white powderMolecular weight:498.46α,α-Trehalose 6-phosphate potassium
CAS:α,α-Trehalose 6-phosphate potassium is an anti-hyperglycemic glucose analogue. Acting as a metabolic sensor, it is converted to trehalose via T6PP and is used in research for diabetes, carbon homeostasis, and growth regulation.Formula:C12H21K2O14PPurity:99.97%Color and Shape:White SolidMolecular weight:498.46Trehalose 6-phosphate dipotassium salt
CAS:Formula:C12H21K2O14PPurity:95%Color and Shape:SolidMolecular weight:498.4571Trehalose 6-Phosphate Dipotassium Salt
CAS:Stability Hygroscopic
Applications Trehalose 6-Phosphate Potassium Salt is an intermediate in the synthesis of D-(+)-Trehalose (T718750), a disaccharide composed of two α-glucose units. D-(+)-Trehalose is used in many processed foods as well as in biopharmaceutical monoclonal antibody formulations. When plants’ sugar levels are low, they reduce their investment in fatty acid synthesis. Trehalose 6-phoshate (T6P) regulates oil synthesis in plants. (Chem. and Eng. News p. 9 Oct. 1, (2018))
References Bosquillon, C. et al.: J. Cont. Rel., 99, 357 (2004); Arakawa, T. et al.: Adv. Drug Deliv. Rev., 46, 307 (2001); Singh, S.K. et al.: Pharmac. Res., 28, 873 (2011); Chem. and Eng. News p. 9 Oct. 1, (2018)Formula:C12H21K2O14PColor and Shape:NeatMolecular weight:498.46Trehalose-6-phosphate dipotassium
CAS:Trehalose-6-phosphate dipotassium salt is a natural sugar that is found in plants, animals, and fungi. It functions as a carbohydrate reserve and protects cells against osmotic stress. Trehalose-6-phosphate dipotassium salt can be synthesized by the enzyme trehalase from the sugar trehalose and 6-phosphate. It has been shown to protect cells from weevil infestation, which may be due to its ability to produce abiotic or biotic stress. Trehalose-6-phosphate dipotassium salt can be purified using hydrophilic interaction chromatography on an on-line system.Formula:C12H21O14PK2Purity:Min. 95%Color and Shape:White PowderMolecular weight:498.46 g/mol
