CAS 136725-55-8

Pyrrolidine, 3-fluoro-, hydrochloride (1:1), (3R)-

Description:

Pyrrolidine, 3-fluoro-, hydrochloride (1:1), (3R)- is a chemical compound characterized by its pyrrolidine ring structure, which is a five-membered saturated heterocycle containing one nitrogen atom. The presence of a fluorine atom at the third carbon position of the pyrrolidine ring imparts specific reactivity and biological properties. As a hydrochloride salt, it is typically encountered in a crystalline form, enhancing its solubility in water and making it suitable for various applications, particularly in pharmaceutical contexts. The (3R)- designation indicates the specific stereochemistry of the compound, which can influence its pharmacological activity and interactions with biological systems. Pyrrolidine derivatives are often studied for their potential in medicinal chemistry, particularly in the development of drugs targeting neurological and psychiatric disorders. Safety and handling precautions are essential, as with many chemical substances, due to potential toxicity and reactivity. Overall, this compound exemplifies the importance of structural features in determining the properties and applications of organic molecules in chemistry and pharmacology.

Formula: C₄H₈FN·ClH

InChI: InChI=1S/C4H8FN.ClH/c5-4-1-2-6-3-4;/h4,6H,1-3H2;1H/t4-;/m1./s1

InChI key: InChIKey=LENYOXXELREKGZ-PGMHMLKASA-N

SMILES: F[C@@H]1CCNC1.Cl

Synonyms:

• (-)-3-Fluoropyrrolidine hydrochloride
• (R)-(-)-3-Fluoropyrrolidine hydrochloride
• (R)-3-Fluoropyrrolidine HCl
• 3(R)-fluoropyrrolidine(HCl)
• 3-(R)-Fluoropyrrolidine hydrochloride
• Pyrrolidine, 3-fluoro-, hydrochloride (1:1), (3R)-
• Pyrrolidine, 3-fluoro-, hydrochloride, (3R)-
• Pyrrolidine, 3-fluoro-, hydrochloride, (R)-
• (3R)-3-Fluoropyrrolidine hydrochloride

(R)-3-Fluoropyrrolidine Hydrochloride

CAS: 136725-55-8

Formula: C₄H₈FN·HCl

Purity: >98.0%(qNMR)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 125.57

Ref: 3B-F1346

(R)-(-)-3-Fluoropyrrolidine hydrochloride, 97%

CAS: 136725-55-8

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₄H₉ClFN

Purity: 97%

Color and Shape: White to brown or pale pink, Crystals or powder or crystalline powder

Molecular weight: 125.57

Ref: 02-H26947

(R)-3-Fluoropyrrolidine hydrochloride

CAS: 136725-55-8

Formula: C₄H₉ClFN

Purity: 97%

Color and Shape: Solid

Molecular weight: 125.5724

Ref: IN-DA00129T

(3R)-(-)-3-Fluoropyrrolidine hydrochloride

CAS: 136725-55-8

(3R)-(-)-3-Fluoropyrrolidine hydrochloride

Formula: C₄H₈FN·ClH

Purity: 98%

Color and Shape: Solid

Molecular weight: 125.57236

Ref: 54-PC3455

(R)-3-Fluoropyrrolidine hydrochloride

CAS: 136725-55-8

(R)-3-Fluoropyrrolidine hydrochloride is a proline analog that is orally bioavailable and selective for dipeptidyl peptidase. It shows good pharmacokinetic properties and has been shown to be a potent inhibitor of both cyclohexylglycine and amides, two enzymes involved in the metabolism of proline. The drug has also been shown to be an excellent substrate for dipeptidyl peptidase, an enzyme involved in the degradation of dipeptides. (R)-3-Fluoropyrrolidine hydrochloride has not yet been tested as an inhibitor of peptidases other than dipeptidyl peptidase. (R)-3-Fluoropyrrolidine hydrochloride is currently undergoing Phase II clinical trials.

Formula: C₄H₉ClFN

Purity: Min. 98%

Molecular weight: 125.57 g/mol

Ref: 3D-FF50542

R-(-)-3-Fluoropyrrolidine hydrochloride

CAS: 136725-55-8

Formula: C₄H₉ClFN

Purity: 97%

Color and Shape: Solid

Molecular weight: 125.57

Ref: 10-F013156

(R)-3-Fluoropyrrolidine HCl

CAS: 136725-55-8

(R)-(-)-3-Fluoropyrrolidine Hydrochloride

Formula: C₄H₉ClFN

Purity: 98%

Molecular weight: 125.57

Ref: IN-DG27478