CAS 136790-76-6
:(11α)-16,16-Difluoro-11-hydroxy-9,15-dioxoprostan-1-oic acid
Description:
(11α)-16,16-Difluoro-11-hydroxy-9,15-dioxoprostan-1-oic acid, with CAS number 136790-76-6, is a synthetic compound that belongs to the class of prostaglandin analogs. This substance is characterized by the presence of two fluorine atoms at the 16 position, a hydroxyl group at the 11 position, and a dioxo functional group at the 9 and 15 positions of the prostanoic acid structure. These modifications contribute to its unique biological activity, which may include anti-inflammatory and analgesic properties. The compound's structural features suggest it may interact with specific receptors in the body, potentially influencing various physiological processes. Its solubility, stability, and reactivity can vary based on the functional groups present, making it important for applications in pharmaceutical research and development. As with many synthetic compounds, safety and handling precautions are essential due to potential biological effects and toxicity. Further studies are often required to fully elucidate its pharmacological profile and therapeutic potential.
Formula:C20H32F2O5
InChI:InChI=1S/C20H32F2O5/c1-2-3-12-20(21,22)18(25)11-10-15-14(16(23)13-17(15)24)8-6-4-5-7-9-19(26)27/h14-15,17,24H,2-13H2,1H3,(H,26,27)/t14-,15-,17-/m1/s1
InChI key:InChIKey=DBVFKLAGQHYVGQ-BFYDXBDKSA-N
SMILES:C(CC(C(CCCC)(F)F)=O)[C@@H]1[C@@H](CCCCCCC(O)=O)C(=O)C[C@H]1O
Synonyms:- RU 0211
- Prostan-1-oic acid, 16,16-difluoro-11-hydroxy-9,15-dioxo-, (11α)-
- Lubiprostone
- (11α)-16,16-Difluoro-11-hydroxy-9,15-dioxoprostan-1-oic acid
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Found 12 products.
Lubiprostone-d7 (Mixture of Tautomeric Isomers)
CAS:Formula:C20H25D7F2O5Color and Shape:White To Off-White SolidMolecular weight:397.51Lubiprostone
CAS:Lubiprostone (RU-0211), an activator of ClC-2 chloride channels, is used in the therapy of idiopathic chronic constipation.Formula:C20H32F2O5Purity:97.31% - 98.54%Color and Shape:SolidMolecular weight:390.46Lubiprostone
CAS:7-((1R,2R,3R)-2-(4,4-Difluoro-3-oxooctyl)-3-hydroxy-5-oxocyclopentyl)heptanoic acidFormula:C20H32F2O5Purity:98%Molecular weight:390.46Lubiprostone
CAS:Formula:C20H32F2O5Purity:>97.0%(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:390.47Lubiprostone (ring open)
CAS:Lubiprostone is a drug that has been approved in the United States for the treatment of irritable bowel syndrome with constipation. It is a synthetic analog of prostaglandin E1 (PGE1) that acts to increase natural fluid secretion into the bowel by activating ClC-2 chloride channels on the apical surface of intestinal cells. Lubiprostone also increases mitochondrial membrane potential and inhibits atherosclerotic lesion formation. In a clinical trial, patients were randomly assigned to receive either lubiprostone or placebo for six weeks. The lubiprostone group had significant improvement in their symptoms and quality of life compared to those who received placebo. Results from this study suggest that lubiprostone may be an effective treatment for patients with bowel disease.Formula:C20H32F2O5Purity:Min. 95%Color and Shape:PowderMolecular weight:390.46 g/molProstan-1-oic acid, 16,16-difluoro-11-hydroxy-9,15-dioxo-, (11α)-
CAS:Formula:C20H32F2O5Purity:98%Color and Shape:SolidMolecular weight:390.4619Lubiprostone Related Compound 8
CAS:Formula:C20H32F2O5Color and Shape:White To Off-White SolidMolecular weight:390.47Ref: 4Z-L-2114
Discontinued product
