CAS 137234-62-9: Voriconazole

Description: Voriconazole is an antifungal medication primarily used to treat serious fungal infections, particularly those caused by Aspergillus species and Candida. It belongs to the triazole class of antifungals, which function by inhibiting the enzyme lanosterol 14α-demethylase, crucial for ergosterol synthesis in fungal cell membranes. Voriconazole is characterized by its broad-spectrum activity against various fungi, making it effective in both invasive and non-invasive infections. The compound is typically administered orally or intravenously and is known for its good bioavailability and tissue penetration. Its pharmacokinetics can be influenced by factors such as age, liver function, and concurrent medications, necessitating careful monitoring of drug levels in some patients. Voriconazole is also associated with potential side effects, including visual disturbances, hepatotoxicity, and skin reactions. Due to its specific mechanism of action and side effect profile, voriconazole is often reserved for cases where other antifungal treatments are ineffective or inappropriate.

Formula: C₁₆H₁₄F₃N₅O

InChI: InChI=1S/C16H14F3N5O/c1-10(15-14(19)5-20-7-22-15)16(25,6-24-9-21-8-23-24)12-3-2-11(17)4-13(12)18/h2-5,7-10,25H,6H2,1H3/t10-,16+/m0/s1

InChI key: InChIKey=BCEHBSKCWLPMDN-MGPLVRAMSA-N

SMILES: FC1=CC=C(C(F)=C1)C(O)(CN2N=CN=C2)C(C=3N=CN=CC3F)C

Synonyms:

• (2R,3S)-2-(2,4-Difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1,2,4-triazol-1-yl)butan-2-ol
• (2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol
• (2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol L(-)-Camphorsulfonate
• (αR,βS)-α-(2,4-Difluorophenyl)-5-fluoro-β-methyl-α-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol
• 2-(2,4-Difluorophenyl)-3-(5-Fluoropyrimidin-4-Yl)-1-(1H-1,2,4-Triazol-1-Yl)Butan-2-Ol
• 4-Pyrimidineethanol, α-(2,4-difluorophenyl)-5-fluoro-β-methyl-α-(1H-1,2,4-triazol-1-ylmethyl)-, (αR,βS)-
• 4-Pyrimidineethanol, α-(2,4-difluorophenyl)-5-fluoro-β-methyl-α-(1H-1,2,4-triazol-1-ylmethyl)-, [R-(R*,S*)]-
• Drg 0301
• G-573
• Uk 109496
• Vfend
• Voriconazol
• (2R,3S)-2-(2,4-Difluorophenyl)-3-(5-fluoropyriMidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)-2-butanol L(-)-CaMphorsulfonate
• Voriconazole

Voriconazole CRS

CAS: 137234-62-9

• Formula: C₁₆H₁₄F₃N₅O
• Color and Shape: White. Powder.
• Molecular weight: 349.3105

Voriconazole

CAS: 137234-62-9

Drugs containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure

• Formula: C₁₆H₁₄F₃N₅O
• Color and Shape: White Powder
• Molecular weight: 349.11504

4-Pyrimidineethanol, α-(2,4-difluorophenyl)-5-fluoro-β-methyl-α-(1H-1,2,4-triazol-1-ylmethyl)-, (αR,βS)-

CAS: 137234-62-9

• Formula: C₁₆H₁₄F₃N₅O
• Purity: 99%
• Color and Shape: Solid
• Molecular weight: 349.3105

Voriconazole

CAS: 137234-62-9

Voriconazole (UK-109496) is a triazole antifungal agent that specifically inhibits STEROL 14-ALPHA-DEMETHYLASE and CYTOCHROME P-450 …

• Formula: C₁₆H₁₄F₃N₅O
• Purity: 98% - 99.91%
• Color and Shape: White To Off White Crystalline Powder
• Molecular weight: 349.31

Voriconazole

CAS: 137234-62-9

• Formula: C₁₆H₁₄F₃N₅O
• Purity: 98.0 - 102.0 %
• Color and Shape: White to off-white crystalline powder
• Molecular weight: 349.31

Voriconazole-d3

CAS: 137234-62-9

• Formula: C₁₆H₁₁D₃F₃N₅O
• Color and Shape: White To Off-White Solid
• Molecular weight: 352.34

Voriconazole

CAS: 137234-62-9

• Molecular weight: 349.31g/mol

Voriconazole

CAS: 137234-62-9

• Purity: 99.43%
• Molecular weight: 349.31g/mol

Voriconazole

CAS: 137234-62-9

• Formula: C₁₆H₁₄F₃N₅O
• Color and Shape: White To Off-White Solid
• Molecular weight: 349.32

Voriconazole

CAS: 137234-62-9

• Formula: C₁₆H₁₄F₃N₅O
• Color and Shape: Neat
• Molecular weight: 349.31

Voriconazole

CAS: 137234-62-9

• Formula: C₁₆H₁₄F₃N₅O
• Purity: >98.0%(HPLC)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 349.32

Voriconazole

CAS: 137234-62-9

• Formula: C₁₆H₁₄F₃N₅O
• Color and Shape: Neat
• Molecular weight: 349.31

Voriconazole, 98%

CAS: 137234-62-9

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Formula: C₁₆H₁₄F₃N₅O
• Purity: 98%
• Color and Shape: Crystalline powder, White to off-white
• Molecular weight: 349.32

Voriconazole-d6

CAS: 137234-62-9

• Formula: C₁₆H₈D₆F₃N₅O
• Molecular weight: 355.35

Voriconazole Impurity 4

CAS: 137234-62-9

• Formula: C₁₆H₁₃ClF₃N₅OHCl
• Color and Shape: White To Off-White Solid
• Molecular weight: 383.76 36.46

Voriconazole-13C-d3

CAS: 137234-62-9

• Formula: C₁₅₁₃CH₁₁D₃F₃N₅O
• Molecular weight: 353.33

Voriconazole RS

CAS: 137234-62-9

• Color and Shape: White Solid Crystalline Powder

(2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol

CAS: 137234-62-9

• Purity: 98.0%
• Color and Shape: Solid, White to almost white powder
• Molecular weight: 349.3169860839844

Voriconazole

CAS: 137234-62-9

Please enquire for more information about Voriconazole including the price, delivery time and more detailed …

• Formula: C₁₆H₁₄F₃N₅O
• Purity: Min. 95%
• Color and Shape: White Powder
• Molecular weight: 349.31 g/mol

Voriconazole - Bio-X ™

CAS: 137234-62-9

Voriconazole is a synthetic, lipophilic molecule that is used in the treatment of fungal infections. …

• Formula: C₁₆H₁₄F₃N₅O
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 349.31 g/mol