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CAS 1374356-45-2: (s)-g-fitinib

Description:The chemical substance (S)-g-fitinib, with the CAS number 1374356-45-2, is an enantiomer of gefitinib, a well-known tyrosine kinase inhibitor primarily used in the treatment of non-small cell lung cancer (NSCLC). This compound selectively targets the epidermal growth factor receptor (EGFR), inhibiting its activity and thereby interfering with the signaling pathways that promote tumor growth and proliferation. (S)-g-fitinib exhibits a specific stereochemistry that may influence its pharmacological properties, including its potency, efficacy, and side effect profile compared to its racemic counterpart. The substance is characterized by its molecular structure, which includes a quinazoline core, and it is typically administered in oral form. Its solubility, stability, and bioavailability are critical factors that affect its therapeutic application. As with many targeted therapies, understanding the pharmacokinetics and pharmacodynamics of (S)-g-fitinib is essential for optimizing treatment regimens and improving patient outcomes in oncology.

  • Synonyms:
  • 2-Pyridinamine, 3-[(1S)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-
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Ref: IN-DA009YYO

5mg165.00 €
10mg193.00 €
25mg296.00 €
50mg621.00 €
100mgTo inquire
250mgTo inquire
Estimated delivery in United States, on Thursday 6 Mar 2025
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Ref: 4Z-C-123004

5mgTo inquire
10mgTo inquire
25mgTo inquire
50mgTo inquire
100mgTo inquire
Estimated delivery in United States, on Thursday 13 Mar 2025
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(S)-crizotinib

CAS:1374356-45-2

Ref: TM-T6357

2mg47.00 €
5mg70.00 €
10mg96.00 €
25mg159.00 €
50mg227.00 €
100mg354.00 €
1mL*10mM (DMSO)77.00 €
Estimated delivery in United States, on Thursday 13 Mar 2025
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(S)-Crizotinib

Controlled Product
CAS:1374356-45-2

Ref: TR-C785005

5mg478.00 €
10mg873.00 €
Estimated delivery in United States, on Tuesday 18 Mar 2025
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(S)-Crizotinib

CAS:1374356-45-2

Ref: 3D-ZEC35645

25mgDiscontinuedRequest information
50mgDiscontinuedRequest information
100mgDiscontinuedRequest information
Discontinued product
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