CAS 1376162-36-5

C1s-IN-1 (trihydrochloride)

CAS: 1376162-36-5

C1s-IN-1 (trihydrochloride)

Purity: 98%

Molecular weight: 390.74g/mol

Ref: 54-OR1005505

C1s-IN-1 trihydrochloride

CAS: 1376162-36-5

C1s-IN-1 trihydrochloride (Compound A1) is a selective inhibitor of C1s protease with a Ki of 5.8 μM. This compound inhibits the cleavage of C2 by C1s with an IC50 of 85 μM and prevents activation of the classical pathway, with an IC50 of 22 μM. Additionally, C1s-IN-1 trihydrochloride acts as a competitive inhibitor of thrombin, exhibiting a Ki of 51.2 μM.

Formula: C₁₆H₂₂Cl₃N₅

Color and Shape: Solid

Molecular weight: 390.74

Ref: TM-T203458

6-(4-Phenylpiperazin-1-yl)pyridine-3-carboximidamide trihydrochloride

CAS: 1376162-36-5

Versatile small molecule scaffold

Formula: C₁₆H₂₂Cl₃N₅

Purity: Min. 95%

Molecular weight: 390.7 g/mol

Ref: 3D-BFC16236