CAS 137975-06-5

Mozavaptan

Description:

Mozavaptan is a chemical compound classified as a vasopressin receptor antagonist, specifically targeting the V2 receptor subtype. It is primarily investigated for its potential therapeutic applications in treating conditions such as hyponatremia and heart failure. The compound exhibits a unique structure that allows it to effectively inhibit the action of vasopressin, a hormone that regulates water retention in the kidneys. Mozavaptan's mechanism of action involves blocking the reabsorption of water, leading to increased urine output and a subsequent rise in serum sodium levels. In terms of physical properties, it is typically presented as a white to off-white solid, and its solubility profile suggests it is soluble in organic solvents but may have limited solubility in water. Safety and efficacy studies are crucial for understanding its pharmacokinetics and potential side effects. Overall, Mozavaptan represents a significant advancement in the management of fluid balance disorders, although further research is necessary to fully elucidate its clinical benefits and risks.

Formula: C₂₇H₂₉N₃O₂

InChI: InChI=1S/C27H29N3O2/c1-19-9-4-5-10-22(19)26(31)28-21-16-14-20(15-17-21)27(32)30-18-8-13-24(29(2)3)23-11-6-7-12-25(23)30/h4-7,9-12,14-17,24H,8,13,18H2,1-3H3,(H,28,31)

InChI key: InChIKey=WRNXUQJJCIZICJ-UHFFFAOYSA-N

SMILES: C(=O)(N1C=2C(C(N(C)C)CCC1)=CC=CC2)C3=CC=C(NC(=O)C4=C(C)C=CC=C4)C=C3

Synonyms:

• 1H-1-Benzazepine, benzamide deriv.
• 5-(Dimethylamino)-1-[4-(2-methylbenzamido)benzoyl]-2,3,4,5-tetrahydro-1H-benzazepine
• Benzamide, N-[4-[[5-(dimethylamino)-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]carbonyl]phenyl]-2-methyl-
• N-(4-{[5-(dimethylamino)-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]carbonyl}phenyl)-2-methylbenzamide
• Opc 31260
• Mozavaptan

Mozavaptan-d6

CAS: 137975-06-5

Formula: C₂₇H₂₃D₆N₃O₂

Color and Shape: White To Off-White Solid

Molecular weight: 433.58

Ref: 4Z-M-165002

Mozavaptan

CAS: 137975-06-5

Formula: C₂₇H₂₉N₃O₂

Color and Shape: Pale Yellow Solid

Molecular weight: 427.55

Ref: 4Z-M-165001

Mozavaptan

CAS: 137975-06-5

Mozavaptan

Purity: ≥98%

Molecular weight: 427.54g/mol

Ref: 54-BUP06920

Mozavaptan

CAS: 137975-06-5

Mozavaptan (OPC-31260) is a competitive vasopressin receptor antagonist for both V1 and V2 receptors with IC50 of 1.2 μM and 14 nM, respectively.

Formula: C₂₇H₂₉N₃O₂

Purity: 98.98% - 99.12%

Color and Shape: Solid

Molecular weight: 427.54

Ref: TM-T6288

Mozavaptan

CAS: 137975-06-5

Formula: C₂₇H₂₉N₃O₂

Color and Shape: Neat

Molecular weight: 427.54

Ref: TR-M732720

Mozavaptan

Controlled Product

CAS: 137975-06-5

Mozavaptan is a pharmacological agent that acts as a vasopressin V2 receptor antagonist. It is derived through synthetic chemical processes designed to target specific neurohormonal pathways in the body. Mozavaptan exerts its effects by inhibiting the action of vasopressin, a hormone that promotes water reabsorption in the kidneys. By blocking the vasopressin receptors, it enhances water excretion and corrects imbalances in electrolyte levels, particularly addressing conditions like hyponatremia.

Formula: C₂₇H₂₉N₃O₂

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 427.54 g/mol

Ref: 3D-FD71413

Benzamide, N-[4-[[5-(dimethylamino)-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]carbonyl]phenyl]-2-methyl-

CAS: 137975-06-5

Formula: C₂₇H₂₉N₃O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 427.5381

Ref: IN-DA0017QW