CAS 138-14-7
:Deferoxamine mesylate
Description:
Deferoxamine mesylate is a chelating agent primarily used in the treatment of iron overload conditions, such as those resulting from repeated blood transfusions in patients with conditions like thalassemia or sickle cell disease. It is a water-soluble compound that forms stable complexes with ferric ions, facilitating their excretion from the body. The substance is derived from the bacterium *Streptomyces pilosus* and is characterized by its ability to selectively bind iron, thereby reducing its toxicity and preventing organ damage. Deferoxamine mesylate is typically administered via subcutaneous or intravenous routes, and its pharmacokinetics involve rapid distribution and renal excretion. The compound is known for its relatively low toxicity profile, although potential side effects may include allergic reactions, gastrointestinal disturbances, and effects on vision with prolonged use. Its effectiveness in managing iron overload has made it a critical therapeutic agent in hematology and oncology settings.
Formula:C25H48N6O8·CH4O3S
InChI:InChI=1S/C25H48N6O8.CH4O3S/c1-21(32)29(37)18-9-3-6-16-27-22(33)12-14-25(36)31(39)20-10-4-7-17-28-23(34)11-13-24(35)30(38)19-8-2-5-15-26;1-5(2,3)4/h37-39H,2-20,26H2,1H3,(H,27,33)(H,28,34);1H3,(H,2,3,4)
InChI key:InChIKey=IDDIJAWJANBQLJ-UHFFFAOYSA-N
SMILES:S(C)(=O)(=O)O.C(CCC(NCCCCCN(C(C)=O)O)=O)(N(CCCCCNC(CCC(N(CCCCCN)O)=O)=O)O)=O
Synonyms:- Ba 33112
- Butanediamide, N<sup>4</sup>-[5-[[4-[[5-(acetylhydroxyamino)pentyl]amino]-1,4-dioxobutyl]hydroxyamino]pentyl]-N<sup>1</sup>-(5-aminopentyl)-N<sup>1</sup>-hydroxy-, methanesulfonate (1:1)
- Butanediamide, N′-[5-[[4-[[5-(acetylhydroxyamino)pentyl]amino]-1,4-dioxobutyl]hydroxyamino]pentyl]-N-(5-aminopentyl)-N-hydroxy-, monomethanesulfonate (salt)
- DFX mesylate
- Deferoxamine B mesylate
- Deferoxamine Mesilate
- Deferoxamine methanesulfonate
- Deferrioxamine B methanesulfonate
- Deferrioxamine methanesulfonate
- Desferal
- Desferal mesylate
- Desferrioxamine B mesylate
- Desferrioxamine B methanesulfonate
- Desferrioxamine mesilate
- Desferrioxamine mesylate
- Desferrioxamine methanesulfonate
- N'-{5-[acetyl(hydroxy)amino]pentyl}-N-[5-({4-[(5-aminopentyl)(hydroxy)amino]-4-oxobutanoyl}amino)pentyl]-N-hydroxybutanediamide methanesulfonate (1:1)
- N'-{5-[acetyl(hydroxy)amino]pentyl}-N-[5-({4-[(5-aminopentyl)(hydroxy)amino]-4-oxobutanoyl}amino)pentyl]-N-hydroxybutanediamide methanesulfonate (1:2)
- NSC 644468
- Propionohydroxamic acid, N-[5-[3-[(5-aminopentyl)hydroxycarbamoyl]propionamido]pentyl]-3-[[5-(N-hydroxyacetamido)pentyl]carbamoyl]-, methanesulfonate
- Propionohydroxamic acid, N-[5-[3-[(5-aminopentyl)hydroxycarbamoyl]propionamido]pentyl]-3-[[5-(N-hydroxyacetamido)pentyl]carbamoyl]-, monomethanesulfonate (salt)
- See more synonyms
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Found 16 products.
Deferoxamine Mesylate
CAS:Formula:C25H48N6O8·CH4O3SPurity:>97.0%(HPLC)(T)Color and Shape:White to Light yellow powder to crystalMolecular weight:656.79DEFEROXAMINE MESILATE CRS
CAS:DEFEROXAMINE MESILATE CRSFormula:C27H56N6O14S2Molecular weight:752.8953Desferrioxamine mesilate
CAS:Desferrioxamine mesilateFormula:C27H56N6O14S2Color and Shape:Off-WhiteMolecular weight:752.8953Deferoxamine Mesylate
CAS:Non-aromatic organic derivatives of hydrazine or of hydroxylamine for use as drugsFormula:C25H48N6O8·CH4O3SColor and Shape:White Crystalline PowderMolecular weight:656.34148Deferoxamine Mesylate
CAS:Deferoxamine Mesylate (DFOM) is an iron chelator and iron death inhibitor.Formula:C26H52N6O11SPurity:94.68% - 99.94%Color and Shape:White SolidMolecular weight:656.79Deferoxamine mesylate
CAS:Deferoxamine mesylateFormula:C25H48N6O8·CH3SO3HPurity:By hplc: 99.0% by area (Typical Value in Batch COA)Color and Shape:Solid-PowderMolecular weight:656.78967Deferoxamine mesylate
CAS:Formula:C26H52N6O11SPurity:95%Color and Shape:SolidMolecular weight:656.7897Ref: IN-DA007ZDX
5gTo inquire5mg28.00€10mg43.00€25mg52.00€50mg54.00€100mg65.00€250mg107.00€1g234.00€10g932.00€25g1,676.00€50g3,325.00€Desferrioxamine B mesylate
CAS:Formula:C25H48N6O8·CH4O3SPurity:≥ 98.0%Color and Shape:White to almost white powderMolecular weight:656.79Deferoxamine Mesylate
CAS:Deferoxamine MesylateFormula:C26H52N6O11SPurity:≥90%Molecular weight:656.79Deferoxamine Mesylate
CAS:N1-(5-Aminopentyl)-N1-hydroxy-N4-(5-(N-hydroxy-4-((5-(N-hydroxyacetamido)pentyl)amino)-4-oxobutanamido)pentyl)succinamide methanesulfonateFormula:C26H52N6O11SPurity:98%Molecular weight:656.79Deferoxamine Mesylate
CAS:Controlled ProductApplications An iron chelating agent used in therapy for patients with sickle cell diseases and iron overload. Studies suggest that it can exert potential antioxidant neuroprotective effects in stroke patients
References Inati, A. et al.: Am. J. Hematol., 85, 782 (2010); Selim, M.: Translat. Stroke Res., 1, 35 (2010); Cappellini, M.D. et al.: Hemoblobin, 33, 258 (2009);Formula:C25H48N6O8·CH4O3SColor and Shape:NeatMolecular weight:656.79Deferoxamine mesylate
CAS:Deferoxamine mesylate is an iron chelator that is used in the treatment of iron overload and to treat patients with chronic renal failure. Deferoxamine mesylate has been shown to inhibit angiogenesis by inhibiting the basic protein required for this process. It is also known to have a protective effect on myocardial cells, preventing cell death due to lack of oxygen (reactive oxygen species). Deferoxamine mesylate also inhibits neuronal death in a model system. Deferoxamine mesylate binds to DNA and inhibits RNA synthesis, which has led to its use as a fluorescence probe for the detection of DNA binding activity. The drug has also been shown to act as a metal chelate, binding with metals such as iron, copper, and zinc.Formula:C26H52N6O11SPurity:Min. 95 Area-%Color and Shape:PowderMolecular weight:656.79 g/mol
