CAS 138199-51-6

α-Amino-2H-tetrazole-5-acetic acid

Description:

α-Amino-2H-tetrazole-5-acetic acid, with the CAS number 138199-51-6, is a chemical compound characterized by its tetrazole ring structure, which is a five-membered ring containing four nitrogen atoms and one carbon atom. This compound features an amino group and an acetic acid moiety, contributing to its potential as a versatile building block in organic synthesis and medicinal chemistry. It is typically a white to off-white solid that is soluble in water and polar organic solvents, making it useful in various chemical reactions. The presence of both the amino and carboxylic acid functional groups allows for diverse reactivity, including peptide bond formation and other coupling reactions. Additionally, α-amino tetrazoles are of interest in the field of pharmaceuticals due to their potential biological activities, including antimicrobial and antitumor properties. As with many nitrogen-containing compounds, it may exhibit unique properties such as stability under certain conditions and reactivity towards electrophiles and nucleophiles, making it a valuable compound in research and development.

Formula: C₃H₅N₅O₂

InChI: InChI=1S/C3H5N5O2/c4-1(3(9)10)2-5-7-8-6-2/h1H,4H2,(H,9,10)(H,5,6,7,8)

InChI key: InChIKey=UKBRUIZWQZHXFL-UHFFFAOYSA-N

SMILES: C(C(O)=O)(N)C=1NN=NN1

Synonyms:

• (Tetrazol-5-Yl)Glycine
• 1H-Tetrazole-5-acetic acid, α-amino-
• 2-Amino-2-(1H-1,2,3,4-tetrazol-5-yl)acetic acid
• 2-Amino-2-(2H-1,2,3,4-tetrazol-5-yl)acetic acid
• 2-Amino-2-(2H-tetrazol-5-yl)acetic acid
• 2H-Tetrazole-5-acetic acid, α-amino-
• Ly 285265
• amino(2H-tetrazol-5-yl)acetic acid
• α-Amino-2H-tetrazole-5-acetic acid

2H-Tetrazole-5-acetic acid, α-amino-

CAS: 138199-51-6

Formula: C₃H₅N₅O₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 143.1041

Ref: IN-DA00189J

(RS)-(Tetrazol-5-yl)glycine

CAS: 138199-51-6

(RS)-(Tetrazol-5-yl)glycine

Formula: C₃H₅N₅O₂

Purity: ≥95%

Molecular weight: 143.1

Ref: 54-BUP06100

(RS)-(Tetrazol-5-yl)glycine

CAS: 138199-51-6

(RS)-(Tetrazol-5-yl)glycine (LY 285265) is a selective NMDA receptor agonist with EC50 of 99 nM (GluN1/GluN2D) and 1.7 μM (GluN1/GluN2A).

Formula: C₃H₅N₅O₂

Purity: 95.00%

Color and Shape: Solid

Molecular weight: 143.1

Ref: TM-T16801

(RS)-(Tetrazol-5-yl)glycine

Controlled Product

CAS: 138199-51-6

Formula: C₃H₅N₅O₂

Color and Shape: Neat

Molecular weight: 143.104

Ref: TR-R700965

alpha-Amino-2H-tetrazole-5-acetic acid

CAS: 138199-51-6

Alpha-amino-2H-tetrazole-5-acetic acid (AAT) is a neurotoxin that inhibits glutamate receptors and causes neuronal cell death. It also decreases heart function in rats by inhibiting the cardiac sodium channel. AAT has been shown to be effective for inducing neuronal death in Xenopus oocytes, as well as decreasing the expression of certain receptor protein, such as NMDA and AMPA receptor subtypes. AAT is also known to cause apoptosis, which may be due to its inhibition of receptor function.

Formula: C₃H₅N₅O₂

Purity: Min. 95%

Color and Shape: Light (Or Pale) Green To Green Solid

Molecular weight: 143.1 g/mol

Ref: 3D-FA161702