CAS 1384071-99-1

Formula: C22H19F4N7O

InChI: InChI=1S/C22H19F4N7O/c1-11(2)33-20-17(19(27)28-10-29-20)18(32-33)12-3-6-14(7-4-12)30-21(34)31-16-9-13(22(24,25)26)5-8-15(16)23/h3-11H,1-2H3,(H2,27,28,29)(H2,30,31,34)

InChI key: CYORWDWRQMVGHN-UHFFFAOYSA-N

SMILES: CC(C)N1C2=NC=NC(=C2C(=N1)C3=CC=C(C=C3)NC(=O)NC4=C(C=CC(=C4)C(F)(F)F)F)N

1-(4-(4-Amino-1-Isopropyl-1H-Pyrazolo[3,4-D]Pyrimidin-3-Yl)Phenyl)-3-(2-Fluoro-5-(Trifluoromethyl)Phenyl)Urea

CAS: 1384071-99-1

1-(4-(4-Amino-1-Isopropyl-1H-Pyrazolo[3,4-D]Pyrimidin-3-Yl)Phenyl)-3-(2-Fluoro-5-(Trifluoromethyl)Phenyl)Urea

Formula: C₂₂H₁₉F₄N₇O

Purity: >99%

Molecular weight: 473.43

Ref: 54-PC108618

AD80

CAS: 1384071-99-1

AD80

Formula: C₂₂H₁₉F₄N₇O

Purity: ≥98%

Molecular weight: 473.43

Ref: 54-BUP09552

AD80

CAS: 1384071-99-1

1-(4-(4-Amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)phenyl)-3-(2-fluoro-5-(trifluoromethyl)phenyl)urea

Formula: C₂₂H₁₉F₄N₇O

Purity: 99+%

Molecular weight: 473.43

Ref: IN-DG00798649

AD80

CAS: 1384071-99-1

AD80, a multikinase inhibitor, inhibits RET, RAF, SRCand S6K, with greatly reduced mTOR activity.

Formula: C₂₂H₁₉F₄N₇O

Purity: 99.49% - 99.75%

Color and Shape: Solid

Molecular weight: 473.4262

Ref: TM-T4301

AD80

CAS: 1384071-99-1

AD80 is a multi-kinase inhibitor that prevents the phosphorylation and activation of tyrosine kinases. It has been shown to inhibit the proliferation of leukemia cells in vivo. AD80 has been found to be effective against glioblastoma cells and other cancer types, such as melanoma, breast cancer, and lung cancer. AD80 inhibits protein synthesis by binding to the ATP-binding site of the enzyme kinase domain. The solubility data for AD80 shows that it is highly soluble in water and organic solvents.

Formula: C₂₂H₁₉F₄N₇O

Purity: Min. 95%

Molecular weight: 473.43 g/mol

Ref: 3D-JFC07199