CAS 138489-18-6

Carbamimidothioic acid, 3-[3-[2,5-dihydro-4-(1-methyl-1H-indol-3-yl)-2,5-dioxo-1H-pyrrol-3-yl]-1H-indol-1-yl]propyl ester, methanesulfonate (1:1)

Description:

Carbamimidothioic acid, 3-[3-[2,5-dihydro-4-(1-methyl-1H-indol-3-yl)-2,5-dioxo-1H-pyrrol-3-yl]-1H-indol-1-yl]propyl ester, methanesulfonate (1:1), with CAS number 138489-18-6, is a complex organic compound characterized by its unique structural features that include multiple indole and pyrrole moieties. This compound is likely to exhibit properties typical of thioamides, such as potential reactivity in nucleophilic substitution reactions due to the presence of the carbamimidothioic acid functional group. The methanesulfonate moiety suggests it may possess good solubility in polar solvents, which can enhance its bioavailability in pharmaceutical applications. The presence of indole derivatives indicates potential biological activity, as indoles are known for their roles in various biological processes and as precursors to many natural products. Overall, this compound may be of interest in medicinal chemistry, particularly in the development of novel therapeutic agents, although specific biological activities and applications would require further investigation.

Formula: C₂₅H₂₃N₅O₂S·CH₄O₃S

InChI: InChI=1S/C25H23N5O2S.CH4O3S/c1-29-13-17(15-7-2-4-9-19(15)29)21-22(24(32)28-23(21)31)18-14-30(11-6-12-33-25(26)27)20-10-5-3-8-16(18)20;1-5(2,3)4/h2-5,7-10,13-14H,6,11-12H2,1H3,(H3,26,27)(H,28,31,32);1H3,(H,2,3,4)

InChI key: InChIKey=SAWVGDJBSPLRRB-UHFFFAOYSA-N

SMILES: O=C1C(C=2C=3C(N(CCCSC(=N)N)C2)=CC=CC3)=C(C(=O)N1)C=4C=5C(N(C)C4)=CC=CC5.S(C)(=O)(=O)O

Synonyms:

• Carbamimidothioic acid, 3-[3-[2,5-dihydro-4-(1-methyl-1H-indol-3-yl)-2,5-dioxo-1H-pyrrol-3-yl]-1H-indol-1-yl]propyl ester, methanesulfonate (1:1)
• Carbamimidothioic acid, 3-[3-[2,5-dihydro-4-(1-methyl-1H-indol-3-yl)-2,5-dioxo-1H-pyrrol-3-yl]-1H-indol-1-yl]propyl ester, monomethanesulfonate
• Methanesulfonic acid 3-[3-[4-(1-methylindol-3-yl)-2,5-dioxopyrrol-3-yl]indol-1-yl]propyl carbamimidothioate
• Ro 31-8220 mesylate
• Ro 31-8220 methanesulfonate
• Ro31-8220

Ro 31-8220 Mesylate

CAS: 138489-18-6

Formula: C₂₅H₂₃N₅O₂S·CH₄O₃S

Purity: >98.0%(T)(HPLC)

Color and Shape: Orange to Red powder to crystal

Molecular weight: 553.65

Ref: 3B-R0257

Carbamimidothioic acid, 3-[3-[2,5-dihydro-4-(1-methyl-1H-indol-3-yl)-2,5-dioxo-1H-pyrrol-3-yl]-1H-indol-1-yl]propyl ester, methanesulfonate (1:1)

CAS: 138489-18-6

Formula: C₂₆H₂₇N₅O₅S₂

Purity: 99%

Color and Shape: Solid

Molecular weight: 553.6531

Ref: IN-DA0019A0

Bisindolylmaleimide IX methanesulphonate salt

CAS: 138489-18-6

Bisindolylmaleimide IX methanesulphonate salt

Purity: 99%

Molecular weight: 553.65g/mol

Ref: 54-BIMI0821

Ro 31-8220 Mesylate

CAS: 138489-18-6

Ro 31-8220 Mesylate

Purity: ≥98%

Molecular weight: 553.65g/mol

Ref: 54-BUP03001

Bisindolylmaleimide IX methansulfonate

CAS: 138489-18-6

Formula: C₂₅H₂₃N₅O₂S·CH₄O₃S

Molecular weight: 553.7

Ref: 7W-GL4877

Ro 31-8220 Mesylate

CAS: 138489-18-6

Ro 31-8220 Mesylate (Bisindolylmaleimide IX mesylate) is a pan-PKC inhibitor, and also shows potent inhibition against MSK1, MAPKAP-K1b, S6K1, and GSK3β.

Formula: C₂₅H₂₃N₅O₂S·CH₄O₃S

Purity: 98.79% - 99.02%

Color and Shape: Solid

Molecular weight: 553.65

Ref: TM-T6643

Ro 31-8220 Mesylate

Controlled Product

CAS: 138489-18-6

Formula: C₂₅H₂₃N₅O₂S·CH₄O₃S

Color and Shape: Neat

Molecular weight: 553.653

Ref: TR-R637300

Ro 31-8220 mesylate

CAS: 138489-18-6

Ro 31-8220 mesylate is a synthetic compound, which is a potent, selective inhibitor predominantly sourced from rational drug design techniques targeting the phosphodiesterase enzyme family. With its mode of action centered around the inhibition of protein kinase C (PKC) and other related kinases, Ro 31-8220 mesylate disrupts downstream signaling pathways, impacting cellular processes such as proliferation, differentiation, and apoptosis.

Formula: C₂₅H₂₃N₅O₂S·CH₃SO₃H

Purity: Min. 95%

Molecular weight: 553.65 g/mol

Ref: 3D-NFA48918