CAS 138530-94-6

R-(+)-Lansoprazole

Description:

R-(+)-Lansoprazole is a proton pump inhibitor (PPI) primarily used to treat conditions such as gastroesophageal reflux disease (GERD) and peptic ulcers by reducing stomach acid production. It is a chiral compound, with the "R" designation indicating its specific stereochemistry, which is crucial for its biological activity. The molecular formula of R-(+)-Lansoprazole includes carbon, hydrogen, nitrogen, and sulfur atoms, contributing to its complex structure. This compound is typically administered in its racemic form, but the R-enantiomer is often highlighted for its enhanced efficacy. R-(+)-Lansoprazole is characterized by its ability to inhibit the H+/K+ ATPase enzyme in gastric parietal cells, leading to a decrease in gastric acid secretion. It is generally well-absorbed in the gastrointestinal tract and exhibits a relatively short half-life, necessitating multiple doses for sustained therapeutic effect. Additionally, it is important to consider its potential side effects, which may include gastrointestinal disturbances and interactions with other medications. Overall, R-(+)-Lansoprazole plays a significant role in managing acid-related disorders.

Formula: C₁₆H₁₄F₃N₃O₂S

InChI: InChI=1S/C16H14F3N3O2S/c1-10-13(20-7-6-14(10)24-9-16(17,18)19)8-25(23)15-21-11-4-2-3-5-12(11)22-15/h2-7H,8-9H2,1H3,(H,21,22)/t25-/m1/s1

InChI key: InChIKey=MJIHNNLFOKEZEW-RUZDIDTESA-N

SMILES: S(CC1=C(C)C(OCC(F)(F)F)=CC=N1)(=O)C=2NC=3C(N2)=CC=CC3

Synonyms:

• (+)-Lansoprazol
• (+)-Lansoprazole
• (R)-2-[[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole
• (R)-2-[[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]methyl]sulfinyl]-1H-benzimidazole
• 1H-Benzimidazole, 2-[(R)-[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-
• 1H-Benzimidazole, 2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-, (R)-
• 2-[(R)-[3-Methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methylsulfinyl]-1H-benzimidazole
• 2-[(R)-[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole
• Dexilant
• Dexlansoprazole
• Dextrolansoprazole
• T 168390
• Tak 390
• (R)-Lansoprazole

R-(+)-Lansoprazole

CAS: 138530-94-6

Formula: C₁₆H₁₄F₃N₃O₂S

Purity: 97%

Color and Shape: Solid

Molecular weight: 369.3615

Ref: IN-DA007LZ2

R-(+)-Lansoprazole

CAS: 138530-94-6

R-(+)-Lansoprazole

Purity: 99%

Molecular weight: 369.36g/mol

Ref: 54-PC109223

(R)-Lansoprazole

CAS: 138530-94-6

(R)-Lansoprazole

Purity: ≥98%

Molecular weight: 369.36g/mol

Ref: 54-BUP14932

(R)-Lansoprazole (Dexlansoprazole)

CAS: 138530-94-6

Formula: C₁₆H₁₄F₃N₃O₂S

Color and Shape: Off-White Solid

Molecular weight: 369.36

Ref: 4Z-L-037

(R)-Lansoprazole-d4 (Dexlansoprazole-d4)

CAS: 138530-94-6

Formula: C₁₆H₁₀D₄F₃N₃O₂S

Color and Shape: Light Reddish Brown Solid

Molecular weight: 373.39

Ref: 4Z-L-0321

Dexlansoprazole

CAS: 138530-94-6

Formula: C₁₆H₁₄F₃N₃O₂S

Purity: ≥ 98.0%

Color and Shape: White to yellow or beige powder

Molecular weight: 369.36

Ref: 7W-GP3263

Dexlansoprazole

CAS: 138530-94-6

Color and Shape: Neat

Ref: 86-MM3995.00

(R)-Lansoprazole

CAS: 138530-94-6

Formula: C₁₆H₁₄F₃N₃O₂S

Purity: >95.0%(T)(HPLC)

Color and Shape: White to Light yellow to Light orange powder to crystal

Molecular weight: 369.36

Ref: 3B-L0453

(R)-Lansoprazole

CAS: 138530-94-6

(R)-Lansoprazole (T 168390) is the R-isomer of lansoprazole and a substituted benzimidazole prodrug with selective and irreversible proton pump inhibitor

Formula: C₁₆H₁₄F₃N₃O₂S

Purity: 98.09% - 98.99%

Color and Shape: Brown Solid

Molecular weight: 369.36

Ref: TM-T1021

N-Nitroso Lansoprazole EP Impurity C (N-Nitroso Lansoprazole USP Related Compound B (Free Form), N-Nitroso Lansoprazole Sulfide)

CAS: 138530-94-6

Formula: C₁₆H₁₃F₃N₄O₂S

Molecular weight: 382.36

Ref: 4Z-L-0372

(R)-Lansoprazole-d4

Controlled Product

CAS: 138530-94-6, 934294-22-1

Applications The labelled R-enantiomer of Lansoprazole; a gastric proton pump inhibitor. An antiulcerative.
References Figgitt, D., et al.: Drugs, 60, 925 (2000), Katsuki, H., et al.: Eur. J. Clin. Pharmacol., 57, 709 (2001), Barradell, L.B., et al.: Drugs, 44, 225 (1992), Kim, K., et al.: Clin. Pharmacol. Ther., 72, 90 (2002), Niioka, T., et al.: Ther. Drug Monit., 28, 321 (2006),

Formula: C₁₆H₁₀D₄F₃N₃O₂S

Color and Shape: Neat

Molecular weight: 373.39

Ref: TR-L175012

Lansoprazole R-Isomer

CAS: 138530-94-6

Formula: C₁₆H₁₄F₃N₃O₂S

Molecular weight: 369.4

Ref: ST-EA-CP-L11040

(R)-Lansoprazole

CAS: 138530-94-6

Stability Hygroscopic
Applications The R-enantiomer of Lansoprazole; a gastric proton pump inhibitor. An antiulcerative.
References Figgitt, D., et al.: Drugs, 60, 925 (2000), Katsuki, H., et al.: Eur. J. Clin. Pharmacol., 57, 709 (2001), Barradell, L.B., et al.: Drugs, 44, 225 (1992), Kim, K., et al.: Clin. Pharmacol. Ther., 72, 90 (2002), Niioka, T., et al.: Ther. Drug Monit., 28, 321 (2006),

Formula: C₁₆H₁₄F₃N₃O₂S

Color and Shape: Off White To Dark Brown

Molecular weight: 369.36

Ref: TR-L175010

(R)-Lansoprazole

CAS: 138530-94-6

Gastric proton pump inhibitor

Formula: C₁₆H₁₄F₃N₃O₂S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 369.36 g/mol

Ref: 3D-FL24837

R-(+)-LANSOPRAZOLE

CAS: 138530-94-6

Formula: C₁₆H₁₄F₃N₃O₂S

Purity: 97.0%

Molecular weight: 369.36

Ref: 10-F468399