CAS 138530-94-6
:R-(+)-Lansoprazole
Description:
R-(+)-Lansoprazole is a proton pump inhibitor (PPI) primarily used to treat conditions such as gastroesophageal reflux disease (GERD) and peptic ulcers by reducing stomach acid production. It is a chiral compound, with the "R" designation indicating its specific stereochemistry, which is crucial for its biological activity. The molecular formula of R-(+)-Lansoprazole includes carbon, hydrogen, nitrogen, and sulfur atoms, contributing to its complex structure. This compound is typically administered in its racemic form, but the R-enantiomer is often highlighted for its enhanced efficacy. R-(+)-Lansoprazole is characterized by its ability to inhibit the H+/K+ ATPase enzyme in gastric parietal cells, leading to a decrease in gastric acid secretion. It is generally well-absorbed in the gastrointestinal tract and exhibits a relatively short half-life, necessitating multiple doses for sustained therapeutic effect. Additionally, it is important to consider its potential side effects, which may include gastrointestinal disturbances and interactions with other medications. Overall, R-(+)-Lansoprazole plays a significant role in managing acid-related disorders.
Formula:C16H14F3N3O2S
InChI:InChI=1S/C16H14F3N3O2S/c1-10-13(20-7-6-14(10)24-9-16(17,18)19)8-25(23)15-21-11-4-2-3-5-12(11)22-15/h2-7H,8-9H2,1H3,(H,21,22)/t25-/m1/s1
InChI key:InChIKey=MJIHNNLFOKEZEW-RUZDIDTESA-N
SMILES:S(CC1=C(C)C(OCC(F)(F)F)=CC=N1)(=O)C=2NC=3C(N2)=CC=CC3
Synonyms:- (+)-Lansoprazol
- (+)-Lansoprazole
- (R)-2-[[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole
- (R)-2-[[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]methyl]sulfinyl]-1H-benzimidazole
- 1H-Benzimidazole, 2-[(R)-[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-
- 1H-Benzimidazole, 2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-, (R)-
- 2-[(R)-[3-Methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methylsulfinyl]-1H-benzimidazole
- 2-[(R)-[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole
- Dexilant
- Dexlansoprazole
- Dextrolansoprazole
- T 168390
- Tak 390
- (R)-Lansoprazole
- See more synonyms
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Found 18 products.
2-[(R)-[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole
CAS:Formula:C16H14F3N3O2SPurity:97%Color and Shape:SolidMolecular weight:369.3615(R)-Lansoprazole (Dexlansoprazole)
CAS:Formula:C16H14F3N3O2SColor and Shape:Off-White SolidMolecular weight:369.36Dexlansoprazole
CAS:Formula:C16H14F3N3O2SPurity:≥ 98.0%Color and Shape:White to yellow or beige powderMolecular weight:369.36(R)-Lansoprazole-d4 (Dexlansoprazole-d4)
CAS:Formula:C16H10D4F3N3O2SColor and Shape:Light Reddish Brown SolidMolecular weight:373.39(R)-Lansoprazole
CAS:Formula:C16H14F3N3O2SPurity:>95.0%(T)(HPLC)Color and Shape:White to Light yellow to Light orange powder to crystalMolecular weight:369.36(R)-Lansoprazole
CAS:(R)-2-(((3-Methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazoleFormula:C16H14F3N3O2SPurity:98%Molecular weight:369.36(R)-Lansoprazole
CAS:(R)-Lansoprazole (T 168390) is the R-isomer of lansoprazole and a substituted benzimidazole prodrug with selective and irreversible proton pump inhibitorFormula:C16H14F3N3O2SPurity:98.09% - 98.99%Color and Shape:SolidMolecular weight:369.36N-Nitroso Lansoprazole EP Impurity C (N-Nitroso Lansoprazole USP Related Compound B (Free Form), N-Nitroso Lansoprazole Sulfide)
CAS:Formula:C16H13F3N4O2SMolecular weight:382.36(R)-Lansoprazole-d4
CAS:Controlled ProductApplications The labelled R-enantiomer of Lansoprazole; a gastric proton pump inhibitor. An antiulcerative.
References Figgitt, D., et al.: Drugs, 60, 925 (2000), Katsuki, H., et al.: Eur. J. Clin. Pharmacol., 57, 709 (2001), Barradell, L.B., et al.: Drugs, 44, 225 (1992), Kim, K., et al.: Clin. Pharmacol. Ther., 72, 90 (2002), Niioka, T., et al.: Ther. Drug Monit., 28, 321 (2006),Formula:C16H10D4F3N3O2SColor and Shape:NeatMolecular weight:373.39(R)-Lansoprazole
CAS:Stability Hygroscopic
Applications The R-enantiomer of Lansoprazole; a gastric proton pump inhibitor. An antiulcerative.
References Figgitt, D., et al.: Drugs, 60, 925 (2000), Katsuki, H., et al.: Eur. J. Clin. Pharmacol., 57, 709 (2001), Barradell, L.B., et al.: Drugs, 44, 225 (1992), Kim, K., et al.: Clin. Pharmacol. Ther., 72, 90 (2002), Niioka, T., et al.: Ther. Drug Monit., 28, 321 (2006),Formula:C16H14F3N3O2SColor and Shape:NeatMolecular weight:369.36(R)-Lansoprazole
CAS:Gastric proton pump inhibitorFormula:C16H14F3N3O2SPurity:Min. 95%Color and Shape:PowderMolecular weight:369.36 g/mol
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