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CAS 13860-38-3

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1-Methylpseudouridine

Description:
1-Methylpseudouridine is a modified nucleoside that is derived from pseudouridine, which is a naturally occurring nucleoside found in various RNA molecules. This compound features a methyl group attached to the nitrogen atom at the 1-position of the pseudouridine structure, which enhances its stability and influences its biological properties. 1-Methylpseudouridine is known for its role in RNA biology, particularly in the context of tRNA and mRNA modifications, where it can affect the folding, stability, and translation efficiency of RNA. The presence of the methyl group can also impact the interaction of RNA with proteins and other nucleic acids. This compound is of interest in various fields, including molecular biology and therapeutic applications, as it may enhance the efficacy of RNA-based drugs and vaccines. Additionally, its unique structural characteristics make it a valuable tool for studying RNA function and modification. Overall, 1-Methylpseudouridine exemplifies the importance of nucleoside modifications in regulating biological processes.
Formula:C10H14N2O6
InChI:InChI=1S/C10H14N2O6/c1-12-2-4(9(16)11-10(12)17)8-7(15)6(14)5(3-13)18-8/h2,5-8,13-15H,3H2,1H3,(H,11,16,17)/t5-,6-,7-,8+/m1/s1
InChI key:InChIKey=UVBYMVOUBXYSFV-XUTVFYLZSA-N
SMILES:O[C@H]1[C@@H](O[C@H](CO)[C@H]1O)C=2C(=O)NC(=O)N(C)C2
Synonyms:
  • (1S)-1,4-anhydro-1-(1-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-D-ribitol
  • 1,4-Anhydro-1-(1-Methyl-2,4-Dioxo-1,2,3,4-Tetrahydropyrimidin-5-Yl)Pentitol
  • 1-Methyl-5-β-<span class="text-smallcaps">D</span>-ribofuranosyl-2,4(1H,3H)-pyrimidinedione
  • 2,4(1H,3H)-Pyrimidinedione, 1-methyl-5-beta-D-ribofuranosyl-
  • 2,4(1H,3H)-Pyrimidinedione, 1-methyl-5-β-<span class="text-smallcaps">D</span>-ribofuranosyl-
  • 2: PN: WO2017201317 SEQID: 2 claimed DNA
  • N<sup>1</sup>-Methylpseudouridine
  • Nsc 240023
  • U 50228
  • Uracil, 1-methyl-5-β-<span class="text-smallcaps">D</span>-ribofuranosyl-
  • See more synonyms
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