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CAS 13880-05-2

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N-[Tris(hydroxymethyl)methyl]acrylamide

Description:
N-[Tris(hydroxymethyl)methyl]acrylamide, commonly referred to as THAM, is a chemical compound characterized by its acrylamide functional group and multiple hydroxymethyl groups. It is a white to off-white crystalline solid that is soluble in water, making it useful in various aqueous applications. The presence of the tris(hydroxymethyl)methyl group enhances its reactivity and stability, allowing it to participate in polymerization reactions, particularly in the formation of hydrogels and other polymeric materials. THAM is often utilized in biochemistry and molecular biology as a crosslinking agent and in the preparation of polyacrylamide gels for electrophoresis. Its structure contributes to its ability to form stable networks, which are essential for applications in drug delivery and tissue engineering. Additionally, THAM is known for its low toxicity, making it a safer alternative in laboratory settings. Overall, its unique chemical properties and versatility make it a valuable compound in both research and industrial applications.
Formula:C7H13NO4
InChI:InChI=1S/C7H13NO4/c1-2-6(12)8-7(3-9,4-10)5-11/h2,9-11H,1,3-5H2,(H,8,12)
InChI key:InChIKey=MVBJSQCJPSRKSW-UHFFFAOYSA-N
SMILES:C(NC(C=C)=O)(CO)(CO)CO
Synonyms:
  • 2-Acrylamido-2-(hydroxymethyl)-1,3-propanediol
  • 2-propenamide, N-[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]-
  • Acrylamide, N-[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]-
  • N-[1,3-Dihydroxy-2-(hydroxymethyl)-2-propanyl]acrylamide
  • N-[1,3-Dihydroxy-2-(hydroxymethyl)propan-2-yl]acrylamide
  • N-[1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl]prop-2-enamide
  • N-[2-Hydroxy-1,1-bis(hydroxymethyl)ethyl]-2-propenamide
  • N-[2-Hydroxy-1,1-bis(hydroxymethyl)ethyl]propenamide
  • N-[Tris(hydroxymethyl)methyl]acrylamide
  • Tris(hydroxymethyl)acrylamidomethane
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