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CAS 139264-17-8

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Zolmitriptan

Description:
Zolmitriptan is a selective agonist of the serotonin receptor subtype 5-HT_1B and 5-HT_1D, primarily used in the treatment of migraine headaches. It belongs to the triptan class of medications, which are designed to alleviate migraine symptoms by constricting dilated blood vessels in the brain and inhibiting the release of pro-inflammatory neuropeptides. The chemical formula of Zolmitriptan is C_16H_21N_3O_2S, and it features a thiazole ring, an indole moiety, and a secondary amine. Zolmitriptan is typically administered orally or via nasal spray, with a relatively rapid onset of action. Its pharmacokinetics indicate that it has a moderate half-life, allowing for effective management of acute migraine attacks. Common side effects may include dizziness, drowsiness, and sensations of tingling or warmth. Due to its mechanism of action, Zolmitriptan is contraindicated in patients with certain cardiovascular conditions, highlighting the importance of a thorough medical history before use.
Formula:C16H21N3O2
InChI:InChI=1S/C16H21N3O2/c1-19(2)6-5-12-9-17-15-4-3-11(8-14(12)15)7-13-10-21-16(20)18-13/h3-4,8-9,13,17H,5-7,10H2,1-2H3,(H,18,20)/t13-/m0/s1
InChI key:InChIKey=ULSDMUVEXKOYBU-ZDUSSCGKSA-N
SMILES:C(CN(C)C)C=1C=2C(NC1)=CC=C(C[C@@H]3NC(=O)OC3)C2
Synonyms:
  • (S)-4-[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]methyl-2-oxazolidinone
  • 4-({3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}methyl)-1,3-oxazolidin-2-one
  • (4S)-4-[[3-[2-(Dimethylamino)ethyl]-1H-indol-5-yl]methyl]-2-oxazolidinone
  • 2-Oxazolidinone, 4-[[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]methyl]-, (4S)-
  • (4r)-4-[[3-(2-dimethylaminoethyl)-1h-indol-5-yl]methyl]oxazolidin-2-one
  • Zolmitriptan
  • (4S)-4-({3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}methyl)-1,3-oxazolidin-2-one
  • (4R)-4-({3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}methyl)-1,3-oxazolidin-2-one
  • 311C90
  • 2-Oxazolidinone, 4-[[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]methyl]-, (S)-
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