CAS 139264-17-8

Zolmitriptan

Description:

Zolmitriptan is a selective agonist of the serotonin receptor subtype 5-HT_1B and 5-HT_1D, primarily used in the treatment of migraine headaches. It belongs to the triptan class of medications, which are designed to alleviate migraine symptoms by constricting dilated blood vessels in the brain and inhibiting the release of pro-inflammatory neuropeptides. The chemical formula of Zolmitriptan is C_16H_21N_3O_2S, and it features a thiazole ring, an indole moiety, and a secondary amine. Zolmitriptan is typically administered orally or via nasal spray, with a relatively rapid onset of action. Its pharmacokinetics indicate that it has a moderate half-life, allowing for effective management of acute migraine attacks. Common side effects may include dizziness, drowsiness, and sensations of tingling or warmth. Due to its mechanism of action, Zolmitriptan is contraindicated in patients with certain cardiovascular conditions, highlighting the importance of a thorough medical history before use.

Formula: C₁₆H₂₁N₃O₂

InChI: InChI=1S/C16H21N3O2/c1-19(2)6-5-12-9-17-15-4-3-11(8-14(12)15)7-13-10-21-16(20)18-13/h3-4,8-9,13,17H,5-7,10H2,1-2H3,(H,18,20)/t13-/m0/s1

InChI key: InChIKey=ULSDMUVEXKOYBU-ZDUSSCGKSA-N

SMILES: C(CN(C)C)C=1C=2C(NC1)=CC=C(C[C@@H]3NC(=O)OC3)C2

Synonyms:

• (S)-4-[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]methyl-2-oxazolidinone
• 4-({3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}methyl)-1,3-oxazolidin-2-one
• (4S)-4-[[3-[2-(Dimethylamino)ethyl]-1H-indol-5-yl]methyl]-2-oxazolidinone
• 2-Oxazolidinone, 4-[[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]methyl]-, (4S)-
• (4r)-4-[[3-(2-dimethylaminoethyl)-1h-indol-5-yl]methyl]oxazolidin-2-one
• Zolmitriptan
• (4S)-4-({3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}methyl)-1,3-oxazolidin-2-one
• (4R)-4-({3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}methyl)-1,3-oxazolidin-2-one
• 311C90
• 2-Oxazolidinone, 4-[[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]methyl]-, (S)-

Zolmitriptan

CAS: 139264-17-8

Formula: C₁₆H₂₁N₃O₂

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Orange to Green powder to crystal

Molecular weight: 287.36

Ref: 3B-Z0024

ZOLMITRIPTAN CRS

CAS: 139264-17-8

ZOLMITRIPTAN CRS

Ref: 41-Y0001975

Zolmitriptan

CAS: 139264-17-8

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

Formula: C₁₆H₂₁N₃O₂

Color and Shape: White Powder

Molecular weight: 287.16338

Ref: 45-1727009

2-Oxazolidinone, 4-[[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]methyl]-, (4S)-

CAS: 139264-17-8

Formula: C₁₆H₂₁N₃O₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 287.3568

Ref: IN-DA001AL8

Zolmitriptan

CAS: 139264-17-8

Zolmitriptan

Formula: C₁₆H₂₁N₃O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 287.36

Ref: 54-OR1029255

Zolmitriptan

CAS: 139264-17-8

Zolmitriptan targets 5-HT 1B/1D receptors, constricts cranial vessels, inhibits pain signals, and stops pro-inflammatory neuropeptides, alleviating migraines.

Formula: C₁₆H₂₁N₃O₂

Purity: 99.69% - 99.91%

Color and Shape: White Or Kind Of White Powder

Molecular weight: 287.36

Ref: TM-T1092

Zolmitriptan

CAS: 139264-17-8

Formula: C₁₆H₂₁N₃O₂

Molecular weight: 287.36

Ref: 7W-GP8335

Zolmitriptan

CAS: 139264-17-8

Zolmitriptan

Formula: C₁₆H₂₁N₃O₂

Purity: ≥98%

Molecular weight: 287.36

Ref: 54-BUP13630

Zolmitriptan

CAS: 139264-17-8

Formula: C₁₆H₂₁N₃O₂

Color and Shape: Off-White Solid

Molecular weight: 287.36

Ref: 4Z-Z-024

Zolmitriptan

CAS: 139264-17-8

Color and Shape: Neat

Ref: 86-MM0298.00

Zolmitriptan

CAS: 139264-17-8

Formula: C₁₆H₂₁N₃O₂

Molecular weight: 287.36

Ref: ST-EA-CP-Z5000

Zolmitriptan

Controlled Product

CAS: 139264-17-8

Applications Zolmitriptan is a serotonin 5HTID-receptor agonist and used to treat migraine (1,2,3).
References (1) Glen, R.C., et al.: J. Med. Chem., 38, 3566 (1995)(2) Seaber, E., et al.: Brit. J. Clin. Pharmacol., 41, 141 (1996)(3) Tepper, S.J., et al.: Curr. Med. Res. Opin., 15, 254 (1999)

Formula: C₁₆H₂₁N₃O₂

Color and Shape: Neat

Molecular weight: 287.36

Ref: TR-Z639000

Zolmitriptan

CAS: 139264-17-8

5-HT1B/1D serotonin receptor agonist; anti-migraine agent

Formula: C₁₆H₂₁N₃O₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 287.36 g/mol

Ref: 3D-FZ28774

Zolmitriptan - Bio-X ™

CAS: 139264-17-8

Zolmitriptan is a drug that belongs to the class of triptans and is a serotonin agonist. This drug is used for the treatment of migraines and allows for cranial vasoconstriction.

Formula: C₁₆H₂₁N₃O₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 287.36 g/mol

Ref: 3D-BZ164590

(S)-4-[3-(2-Dimethylamino-ethyl)-1H-indol-5-ylmethyl]-oxazolidin-2-one

CAS: 139264-17-8

Formula: C₁₆H₂₁N₃O₂

Purity: 99%

Molecular weight: 287.363

Ref: 10-F036593

Zolmitriptan

CAS: 139264-17-8

Color and Shape: White Solid

Ref: 61-FOR0298.00