CAS 1398046-21-3

4-[4,4-Dimethyl-3-[6-[3-(2-oxazolyl)propyl]-3-pyridinyl]-5-oxo-2-thioxo-1-imidazolidinyl]-3-fluoro-2-(trifluoromethyl)benzonitrile

Description:

The chemical substance known as 4-[4,4-Dimethyl-3-[6-[3-(2-oxazolyl)propyl]-3-pyridinyl]-5-oxo-2-thioxo-1-imidazolidinyl]-3-fluoro-2-(trifluoromethyl)benzonitrile, with the CAS number 1398046-21-3, is a complex organic compound characterized by its diverse functional groups and structural features. It contains a benzonitrile core, which is substituted with a trifluoromethyl group and a fluorine atom, enhancing its electronic properties. The imidazolidinyl moiety contributes to its potential biological activity, while the presence of a pyridine and an oxazole ring suggests possible interactions with biological targets. The compound's thioxo group may impart unique reactivity, making it of interest in medicinal chemistry. Its intricate structure indicates potential applications in pharmaceuticals, particularly in the development of novel therapeutic agents. However, specific physical and chemical properties such as solubility, melting point, and stability would require empirical determination or literature reference for comprehensive characterization.

Formula: C₂₄H₁₉F₄N₅O₂S

InChI: InChI=1S/C24H19F4N5O2S/c1-23(2)21(34)32(17-9-6-14(12-29)19(20(17)25)24(26,27)28)22(36)33(23)16-8-7-15(31-13-16)4-3-5-18-30-10-11-35-18/h6-11,13H,3-5H2,1-2H3

InChI key: InChIKey=KCBJGVDOSBKVKP-UHFFFAOYSA-N

SMILES: S=C1N(C(=O)C(C)(C)N1C=2C=CC(CCCC3=NC=CO3)=NC2)C4=C(F)C(C(F)(F)F)=C(C#N)C=C4

Synonyms:

• Pruxelutamide
• Benzonitrile, 4-[4,4-dimethyl-3-[6-[3-(2-oxazolyl)propyl]-3-pyridinyl]-5-oxo-2-thioxo-1-imidazolidinyl]-3-fluoro-2-(trifluoromethyl)-
• Proxalutamide
• 4-[4,4-Dimethyl-3-[6-[3-(2-oxazolyl)propyl]-3-pyridinyl]-5-oxo-2-thioxo-1-imidazolidinyl]-3-fluoro-2-(trifluoromethyl)benzonitrile
• GT 0918

Proxalutamide

CAS: 1398046-21-3

Proxalutamide is a potent antagonist of the androgen receptor (AR).

Formula: C₂₄H₁₉F₄N₅O₂S

Purity: 99.11%

Color and Shape: Solid

Molecular weight: 517.5

Ref: TM-T15445

Proxalutamide

CAS: 1398046-21-3

Proxalutamide

Purity: ≥98%

Molecular weight: 517.5g/mol

Ref: 54-BUP21022

Proxalutamide

CAS: 1398046-21-3

Proxalutamide is a non-steroidal antiandrogen, which is a compound derived from synthetic chemical processes with a mode of action that involves selective antagonism of androgen receptors. This action effectively inhibits the binding of androgen hormones, such as testosterone, which are critical for the growth and survival of certain types of cancer cells, particularly in prostate cancer.

Formula: C₂₄H₁₉F₄N₅O₂S

Purity: Min. 95%

Molecular weight: 517.5 g/mol

Ref: 3D-YFC04621