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CAS 1398065-86-5

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Clomipramine D3 Hydrochloride

Description:
Clomipramine D3 Hydrochloride is a chemical compound that serves as a tricyclic antidepressant, primarily used in the treatment of obsessive-compulsive disorder (OCD) and depression. It is a deuterated form of clomipramine, which means that some of its hydrogen atoms are replaced with deuterium, a stable isotope of hydrogen. This modification can influence the pharmacokinetics and metabolic stability of the drug. Clomipramine D3 Hydrochloride functions by inhibiting the reuptake of neurotransmitters such as serotonin and norepinephrine, thereby enhancing their availability in the synaptic cleft. The hydrochloride salt form improves its solubility and stability, making it suitable for pharmaceutical formulations. As with other tricyclic antidepressants, it may have side effects, including sedation, weight gain, and anticholinergic effects. Its unique isotopic labeling also makes it valuable in research settings, particularly in pharmacokinetic studies and metabolic tracing. Overall, Clomipramine D3 Hydrochloride represents a specialized variant of a well-known antidepressant with potential applications in both clinical and research contexts.
Formula:C19H24Cl2N2
InChI:InChI=1S/C19H23ClN2.ClH/c1-21(2)12-5-13-22-18-7-4-3-6-15(18)8-9-16-10-11-17(20)14-19(16)22;/h3-4,6-7,10-11,14H,5,8-9,12-13H2,1-2H3;1H/i1D3;
InChI key:WIMWMKZEIBHDTH-NIIDSAIPSA-N
SMILES:[2H]C([2H])([2H])N(C)CCCN1C2=CC=CC=C2CCC3=C1C=C(C=C3)Cl.Cl
Synonyms:
  • Clomipramine-d3 Hydrochloride (N-methyl-d3)
  • Clomipramine D3 Hydrochloride
  • Clomipramine-d
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