CAS 140-63-6

Propamidine isethionate

Description:

Propamidine isethionate, with the CAS number 140-63-6, is a chemical compound primarily recognized for its use as an antimicrobial agent. It is a member of the amidine class of compounds and is characterized by its ability to inhibit the growth of various microorganisms, making it valuable in pharmaceutical formulations, particularly in ophthalmic solutions for treating eye infections. The compound is typically presented as a white to off-white crystalline powder, which is soluble in water and exhibits a slightly alkaline pH. Propamidine isethionate functions by disrupting the cellular processes of bacteria and fungi, thereby exerting its therapeutic effects. Additionally, it is known for its low toxicity profile, which enhances its suitability for topical applications. Its stability under various conditions contributes to its effectiveness in formulations, and it is often combined with other agents to enhance its antimicrobial properties. Overall, propamidine isethionate is an important compound in the field of medicinal chemistry, particularly in the treatment of infections.

Formula: C₁₇H₂₀N₄O₂·2C₂H₆O₄S

InChI: InChI=1S/C17H20N4O2.C2H6O4S/c18-16(19)12-2-6-14(7-3-12)22-10-1-11-23-15-8-4-13(5-9-15)17(20)21;3-1-2-7(4,5)6/h2-9H,1,10-11H2,(H3,18,19)(H3,20,21);3H,1-2H2,(H,4,5,6)

InChI key: InChIKey=GKRUSDNSUNFBSG-UHFFFAOYSA-N

SMILES: C(S(=O)(=O)O)CO.O(CCCOC1=CC=C(C(=N)N)C=C1)C2=CC=C(C(=N)N)C=C2

Synonyms:

• 4,4′-Diamidino-α,ω-diphenoxypropane isethionate
• Benzamidine, 4,4′-(trimethylenedioxy)di-, bis(2-hydroxyethanesulfonate)
• Benzamidine, 4,4′-(trimethylenedioxy)di-, diisethionate
• Benzenecarboximidamide, 4,4′-[1,3-propanediylbis(oxy)]bis-, bis(2-hydroxyethanesulfonate)
• Brolene Drops
• Ethanesulfonic acid, 2-hydroxy-, compd. with 4,4'-(trimethylenedioxy)dibenzamidine (2:1)
• Ethanesulfonic acid, 2-hydroxy-, compd. with 4,4′-(trimethylenedioxy)dibenzamidine
• Ethanesulfonic acid, 2-hydroxy-, compd. with 4,4′-[1,3-propanediylbis(oxy)]bis[benzenecarboximidamide] (2:1)
• M + B 782
• M and B 782
• Propamidine diisethionate
• Propamidine isethionate
• Propamidine isthionate
• p,p′-(Trimethylenedioxy)dibenzamidine bis(β-hydroxyethanesulfonate)
• p,p′-(Trimethylenedioxy)dibenzamidine isethionate

4,4'-(Propane-1,3-diylbis(oxy))dibenzimidamide bis(2-hydroxyethanesulfonate)

CAS: 140-63-6

4,4'-(Propane-1,3-diylbis(oxy))dibenzimidamide bis(2-hydroxyethanesulfonate)

Formula: C₂₁H₃₂N₄O₁₀S₂

Purity: 95%

Molecular weight: 564.64

Ref: 54-OR1045004

Propamidine isethionate

CAS: 140-63-6

Propamidine isethionate is a diamidine antiprotozoal agent used for Acanthamoeba keratitis research, acting by interfering with pathogen DNA synthesis.

Formula: C₁₉H₂₆N₄O₆S

Purity: 99.98%

Color and Shape: White Solid

Molecular weight: 438.50

Ref: TM-T34144

Propamidine Diisetionate

Controlled Product

CAS: 140-63-6

Formula: C₁₇H₂₀N₄O₂C₂H₆O₄S

Color and Shape: Neat

Molecular weight: 564.63

Ref: 86-MM3060.00

Propamidine isetionate

Controlled Product

CAS: 140-63-6

Formula: C₁₇H₂₀N₄O₂·2C₂H₆O₄S

Color and Shape: Neat

Ref: TR-P293095

Propamidine Isethionate

CAS: 140-63-6

Formula: C₁₇H₂₀N₄O₂(C₂H₆O₄S)

Molecular weight: 312.37 : 2(126.1)

Ref: ST-EA-CP-P195001