CAS 1405-10-3

Neomycin sulfate

Description:

Neomycin sulfate is an aminoglycoside antibiotic primarily used for its antibacterial properties. It is derived from the bacterium *Streptomyces fradiae* and is effective against a broad spectrum of Gram-negative and some Gram-positive bacteria. The compound is typically administered topically or orally, often in the form of ointments, creams, or eye drops, due to its potential nephrotoxicity and ototoxicity when used systemically. Neomycin sulfate is characterized by its solubility in water, which facilitates its use in various formulations. The chemical structure features multiple amino groups, contributing to its mechanism of action, which involves binding to bacterial ribosomes and inhibiting protein synthesis. Additionally, neomycin sulfate is often combined with other antibiotics or corticosteroids to enhance therapeutic efficacy. It is important to note that resistance to neomycin can develop, limiting its effectiveness in some bacterial infections. As with any antibiotic, appropriate use is crucial to minimize the risk of resistance and ensure optimal therapeutic outcomes.

Formula: H₂O₄S·xUnspecified

InChI: InChI=1/C23H46N6O13.H2O4S/c24-2-7-13(32)15(34)10(28)21(37-7)40-18-6(27)1-5(26)12(31)20(18)42-23-17(36)19(9(4-30)39-23)41-22-11(29)16(35)14(33)8(3-25)38-22;1-5(2,3)4/h5-23,30-36H,1-4,24-29H2;(H2,1,2,3,4)/t5-,6-,7+,8-,9+,10+,11+,12+,13-,14-,15+,16+,17+,18+,19+,20+,21+,22+,23-;/m1./s1

Synonyms:

• (1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-beta-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2,6-diamino-2,6-dideoxy-alpha-D-glucopyranoside sulfate (1:1)
• (2S,3S,4S,5S,6S)-5-amino-2-(aminomethyl)-6-[(1S,2S,3S,4R,6R)-4,6-diamino-2-[(2R,3S,4R,5S)-4-[(2S,3S,4S,5S,6R)-3-amino-6-(aminomethyl)-4,5-dihydroxy-tetrahydropyran-2-yl]oxy-3-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]oxy-3-hydroxy-cyclohexoxy]tetrahydropyran-3,4-diol,sulfuric acid
• Biosol
• Bykomycin
• Endomixin
• Fradiomycin Sulfate
• Lidamycin Creme
• Myacine
• Mycerin sulfate
• Mycifradin
• Mycifradin N
• Mycifradin Sulfate
• Myciguent
• Neo-Mantle Creme
• Neo-rx
• Neobrettin
• Neofracin
• Neolate
• Neomix
• Neomycin Sulfate
• Neomycin, sulfate (salt)
• Neosulf
• New France F
• Nivemycin
• Nystatin sulfate
• O-2,6-Diamino-2,6-Dideoxy-.Beta.-L-Idopyranosyl-(1.->3)-O-.Beta.-D-Ribofuranosyl-(1->5))-O-(2,6-Diamino-2,6-Dideoxy-.Alpha.-D-Glucopyranosyl-(1->4))-2-Deoxy Sulfate
• Otobiotic
• Quintess-N

Neomycin sulfate

CAS: 1405-10-3

Neomycin sulfate (Framycin sulfate) is a broad-spectrum aminoglycoside antibiotic that blocks the synthesis of bacterial proteins in order to exert

Formula: C₂₃H₄₆N₆O₁₃·3H₂SO₄

Purity: 99.4% - 99.88%

Color and Shape: Yellow Solid

Molecular weight: 908.87

Ref: TM-T0950

Neomycin trisulfate hydrate

CAS: 1405-10-3

Neomycin, one of the many oligosaccharide containing antibiotics, is an aminoglycoside antibiotic found in Streptomyces fradiae (Collins, 2006) with wide spectrum, active against Gram-negative Gram-positive bacteria. Neomycin is commony used as a selection marker in cloning, and is therefore used in growth media to select colonies with the neomycin resistance cassette integrated into their genome. Neomycin is a mixture of neomycin B (Framycetin) and its epimer Neomycin C, the latter component accounting for some 5–15% of the mixture.

Formula: C₂₃H₄₆N₆O₁₃·3H₂SO₄

Purity: Min. 600 Ug/Mg

Color and Shape: White Slightly Yellow Powder

Molecular weight: 908.88 g/mol

Ref: 3D-AN10534

Neomycin trisulfate, Antibiotic for Culture Media Use Only

CAS: 1405-10-3

Neomycin, one of the many oligosaccharide containing antibiotics, is an aminoglycoside antibiotic found in Streptomyces fradiae (Collins, 2006) with wide spectrum, active against Gram-negative Gram-positive bacteria. Neomycin is commony used as a selection marker in cloning, and is therefore used in growth media to select colonies with the neomycin resistance cassette integrated into their genome. Neomycin is a mixture of neomycin B (Framycetin) and its epimer Neomycin C, the latter component accounting for some 5–15% of the mixture.

Formula: C₂₃H₅₂N₆O₂₅S₃

Molecular weight: 908.88 g/mol

Ref: 3D-N-2515

Neomycin sulfate in Water

CAS: 1405-10-3

Water

Ref: BE-BePure-24273YW-1000

Neomycin Sulphate (NMS), 600U/mg

CAS: 1405-10-3

Formula: C₂₃H₄₆N₆O₁₃·3H₂SO₄

Color and Shape: Creamish white to yellowish white, Powder, Clear, Slight yellow

Molecular weight: 908.90

Ref: SR-35282

Neomycin Sulphate (NMS) for cell culture, Endotoxin (BET) 0.05EU/mg

CAS: 1405-10-3

Formula: C₂₃H₄₆N₆O₁₃·3H₂SO₄

Color and Shape: Creamish white to yellowish white, Powder, Clear, Slight yellow

Molecular weight: 908.90

Ref: SR-69599

Fradiomycin Sulfate RS

CAS: 1405-10-3

Color and Shape: White To Light Yellow Solid Powder

Ref: 2K-7000830021