CAS 1405-10-3

Neomycin sulfate

Description:

Neomycin sulfate is an aminoglycoside antibiotic primarily used for its antibacterial properties. It is derived from the bacterium *Streptomyces fradiae* and is effective against a broad spectrum of Gram-negative and some Gram-positive bacteria. The compound is typically administered topically or orally, often in the form of ointments, creams, or eye drops, due to its potential nephrotoxicity and ototoxicity when used systemically. Neomycin sulfate is characterized by its solubility in water, which facilitates its use in various formulations. The chemical structure features multiple amino groups, contributing to its mechanism of action, which involves binding to bacterial ribosomes and inhibiting protein synthesis. Additionally, neomycin sulfate is often combined with other antibiotics or corticosteroids to enhance therapeutic efficacy. It is important to note that resistance to neomycin can develop, limiting its effectiveness in some bacterial infections. As with any antibiotic, appropriate use is crucial to minimize the risk of resistance and ensure optimal therapeutic outcomes.

Formula: H₂O₄S·xUnspecified

InChI: InChI=1/C23H46N6O13.H2O4S/c24-2-7-13(32)15(34)10(28)21(37-7)40-18-6(27)1-5(26)12(31)20(18)42-23-17(36)19(9(4-30)39-23)41-22-11(29)16(35)14(33)8(3-25)38-22;1-5(2,3)4/h5-23,30-36H,1-4,24-29H2;(H2,1,2,3,4)/t5-,6-,7+,8-,9+,10+,11+,12+,13-,14-,15+,16+,17+,18+,19+,20+,21+,22+,23-;/m1./s1

Synonyms:

• (1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-beta-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2,6-diamino-2,6-dideoxy-alpha-D-glucopyranoside sulfate (1:1)
• (2S,3S,4S,5S,6S)-5-amino-2-(aminomethyl)-6-[(1S,2S,3S,4R,6R)-4,6-diamino-2-[(2R,3S,4R,5S)-4-[(2S,3S,4S,5S,6R)-3-amino-6-(aminomethyl)-4,5-dihydroxy-tetrahydropyran-2-yl]oxy-3-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]oxy-3-hydroxy-cyclohexoxy]tetrahydropyran-3,4-diol,sulfuric acid
• Biosol
• Bykomycin
• Endomixin
• Fradiomycin Sulfate
• Lidamycin Creme
• Myacine
• Mycerin sulfate
• Mycifradin
• Mycifradin N
• Mycifradin Sulfate
• Myciguent
• Neo-Mantle Creme
• Neo-rx
• Neobrettin
• Neofracin
• Neolate
• Neomix
• Neomycin Sulfate
• Neomycin, sulfate (salt)
• Neosulf
• New France F
• Nivemycin
• Nystatin sulfate
• O-2,6-Diamino-2,6-Dideoxy-.Beta.-L-Idopyranosyl-(1.->3)-O-.Beta.-D-Ribofuranosyl-(1->5))-O-(2,6-Diamino-2,6-Dideoxy-.Alpha.-D-Glucopyranosyl-(1->4))-2-Deoxy Sulfate
• Otobiotic
• Quintess-N

Fradiomycin Sulfate

CAS: 1404-04-2, 1405-10-3

Formula: C₂₃H₄₆N₆O₁₃·3H₂SO₄

Purity: >97.0%(N)

Color and Shape: White to Orange to Green powder to crystal

Molecular weight: 908.87

Ref: 3B-F0649

Neomycin sulfate hydrate

CAS: 1405-10-3

Neomycin sulfate is an aminoglycoside antibiotic and calcium channel protein inhibitor. Neomycin sulfate also binds to prokaryotic ribosomes inhibiting translation and is effective against gram-positive and gram-negative bacteria. Neomycin sulfate inhibits Phospholipase C via binding to inositol pho

Formula: C₂₃H₄₈N₆O₁₇S

Molecular weight: 712.72

Ref: 02-J61499

Neomycin sulfate, 50 mg/ml in distilled water, sterile-filtered

CAS: 1405-10-3

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Ref: 02-J67011

NEOMYCIN SULFATE FOR MICROBIOLOGICAL ASSAY CRS

CAS: 1405-10-3

NEOMYCIN SULFATE FOR MICROBIOLOGICAL ASSAY CRS

Formula: C₂₃H₄₈N₆O₁₇S

Molecular weight: 712.7222

Ref: 41-N0401000

NEOMYCIN SULFATE CRS

CAS: 1405-10-3

NEOMYCIN SULFATE CRS

Formula: C₂₃H₄₈N₆O₁₇S

Color and Shape: White. Light Yellow. Powder.

Molecular weight: 712.7222

Ref: 41-N0400000

THIRD INTERNATIONAL STANDARD FOR NEOMYCIN

CAS: 1405-10-3

THIRD INTERNATIONAL STANDARD FOR NEOMYCIN

Formula: C₂₃H₄₈N₆O₁₇S

Molecular weight: 712.7222

Ref: 41-ISA46707

Neomycin Sulfate

CAS: 1405-10-3

Antibiotics nesoi

Formula: C₂₃H₄₆N₆O₁₃·xH₂SO₄

Color and Shape: White Light Yellow Powder

Molecular weight: 614.31229

Ref: 45-1458009

Neomycin (sulfate)

CAS: 1405-10-3

Formula: C₂₃H₄₈N₆O₁₇S

Purity: 97%

Color and Shape: Solid

Molecular weight: 712.7222

Ref: IN-DA001CJZ

Neomycin sulphate

CAS: 1405-10-3

Neomycin sulphate

Formula: C₂₃H₄₆N₆O₁₃·H₂SO₄

Color and Shape: White Solid

Molecular weight: 712.72222

Ref: 54-BIN0135

Neomycin sulfate

CAS: 1405-10-3

Neomycin sulfate

Purity: ≥98%

Molecular weight: 908.87g/mol

Ref: 54-BUP19775

Neomycin sulfate

CAS: 1405-10-3

Formula: C₂₃H₄₆N₆O₁₃·3H₂SO₄·xH₂O

Purity: ≥ 650IU/mg (dried basis)

Color and Shape: White to light-yellow powder

Molecular weight: 908.87 (anhydrous)

Ref: 7W-GA6251

Neomycin sulfate, USP grade

CAS: 1405-10-3

Formula: C₂₃H₄₆N₆O₁₃·3H₂SO₄·xH₂O

Color and Shape: White to light-yellow powder

Molecular weight: 908.87 (anhydrous)

Ref: 7W-GA8887

Neomycin sulfate, Ph. Eur. grade

CAS: 1405-10-3

Formula: C₂₃H₄₆N₆O₁₃·3H₂SO₄·xH₂O

Purity: ≤ 5.0%

Color and Shape: White or yellowish-white powder, hygroscopic

Molecular weight: 908.87 (anhydrous)

Ref: 7W-GP4875

Neomycin sulfate, USP grade, low endotoxin

CAS: 1405-10-3

Formula: C₂₃H₄₆N₆O₁₃·3H₂SO₄·xH₂O

Purity: ≤ 5.0%

Color and Shape: White to light-yellow powder

Molecular weight: 908.87 (anhydrous)

Ref: 7W-GP8418

Neomycin sulfate (Standard)

CAS: 1405-10-3

Neomycin sulfate (Standard) is the certified analytical reference standard of Neomycin sulfate developed for quantitative analysis, quality control, and biochemical research applications, and as a broad-spectrum aminoglycoside antibiotic, Neomycin sulfate (Framycin sulfate) inhibits bacterial protein synthesis by binding ribosomal subunits, while being widely applied as a selective agent for screening prokaryotic and eukaryotic cells harboring Neo resistance genes.

Formula: C₂₃H₄₆N₆O₁₃·3H₂SO₄

Color and Shape: White Solid

Molecular weight: 908.87

Ref: TM-TMSM-1715

Neomycin sulfate

Controlled Product

CAS: 1405-10-3

Formula: C₂₃H₄₆N₆O₁₃

Color and Shape: Neat

Molecular weight: 926.88

Ref: 04-C15500900

Neomycin sulfate 100 µg/mL in Water

Controlled Product

CAS: 1405-10-3

Formula: C₂₃H₄₆N₆O₁₃

Color and Shape: Single Solution

Molecular weight: 926.88

Ref: 04-A15500900WA-100

Fradiomycin Sulfate RS

CAS: 1405-10-3

Color and Shape: White To Light Yellow Solid Powder

Ref: 2K-700083002

Neomycin sulfate

CAS: 1405-10-3

Formula: C₂₃H₄₆N₆O₁₃(H₂SO₄)

Molecular weight: 614.7 : 3(98.1)

Ref: ST-EA-CP-N53020

Neomycin Trisulfate Hydrate

Controlled Product

CAS: 1405-10-3

Applications Neomycin is an aminoglycoside antibiotic found in many topical medications. Neomycin has been used as a preventive measure for hepatic encephalopathy and hypercholesterolemia.

Formula: C₂₃H₄₆N₆O₁₃H₂SO₄·xH₂O

Color and Shape: Neat

Molecular weight: 908.88 (anhydrous)

Ref: TR-N389975