CAS 1405-41-0

Gentamicin sulfate

Description:

Gentamicin sulfate is an aminoglycoside antibiotic primarily used to treat various bacterial infections, particularly those caused by Gram-negative bacteria. It is derived from the bacterium Micromonospora purpurea and is known for its broad-spectrum antimicrobial activity. The substance appears as a white to pale yellow powder and is soluble in water, which facilitates its administration via injection or topical application. Gentamicin sulfate works by inhibiting bacterial protein synthesis, leading to cell death. Its pharmacokinetics involve renal excretion, necessitating careful monitoring of kidney function during treatment to avoid toxicity. Common side effects may include nephrotoxicity and ototoxicity, particularly with prolonged use or high doses. Gentamicin sulfate is often used in combination with other antibiotics to enhance efficacy against resistant strains. Due to its effectiveness and relatively low cost, it remains a critical option in the treatment of serious infections, especially in hospital settings. However, resistance can develop, necessitating judicious use and susceptibility testing when appropriate.

Formula: H₂O₄S·xUnspecified

InChI: InChI=1/C19H39N5O7.H2O4S/c1-19(27)7-28-18(13(26)16(19)24-2)31-15-11(23)5-10(22)14(12(15)25)30-17-9(21)4-3-8(6-20)29-17;1-5(2,3)4/h8-18,24-27H,3-7,20-23H2,1-2H3;(H2,1,2,3,4)/t8-,9+,10-,11+,12-,13+,14+,15-,16+,17+,18+,19-;/m0./s1

Synonyms:

• 4,6-diamino-3-{[3-deoxy-4-C-methyl-3-(methylamino)pentopyranosyl]oxy}-2-hydroxycyclohexyl 2-amino-2,3,4,6,7-pentadeoxy-6-(methylamino)heptopyranoside
• Alcomicin
• Bristagen
• Cidomycin
• Dispagent
• Duragentam
• Eltacin
• Garamycin
• Garasent
• Garasol
• Genoptic
• Genoptics.O.P.
• Gent-Ophtal
• Genta Swift
• Gentacidin
• Gentacin
• Gentak
• Gentalin
• Gentalline
• Gentalyn
• Gentamicin 2,5-Sulfate Hydrate
• Gentamicin C complex sulfate
• Gentamicin Solution 10Mg/Ml Sterile*Filtered
• Gentamicin Solution Cell Culture Tested
• Gentamicin Standard Solution
• Gentamicin Sulfate
• Gentamicin Sulfate Cell Culture Tested
• Gentamicin Sulfate From Micromonospora Purpurea
• Gentamicin Sulfate Solution Hybri-Max*50Mg/Ml
• Gentamicin Sulphate
• Gentamicin sulfate Micromonospora purpurea
• Gentamicin sulfate, USP Grade
• Gentamicin, Sulfat (Salz)
• Gentamicin, sulfate (salt)
• Gentamicina, Sulfato (Sal)
• Gentamicine, Sulfate (Sel)
• Gentamicinsolution
• Gentamina
• Gentamycin Sulphate
• Gentamycin sulfate
• Gentamycin, sulfate (salt)
• Gentibioptal
• Genticin
• Genticyn
• Gentocin
• Gentogram
• Gentrasul
• Geramycin
• Intragen
• Lugacin
• Nichogencin
• Nsc-82261
• Ophtagram
• Pangram
• Refobacin
• Refobacin 10
• Refobacin L
• Sch9724
• Septopal
• Sulmycin
• U-gencin

Gentamicin Sulfate

CAS: 1403-66-3, 1405-41-0

Color and Shape: White to Light yellow powder to crystal

Ref: 3B-G0383

Gentamicin sulfate, 20 mg/ml in distilled water, sterile-filtered

CAS: 1405-41-0

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₆₀H₁₂₅N₁₅O₂₅S

Color and Shape: Clear solution

Molecular weight: 1488.80

Ref: 02-J67488

Gentamicin sulfate, 600 I.U./mg

CAS: 1405-41-0

Gentamicin sulfate, 1405-41-0, is an antibiotic used for the prevention of bacterial contamination of cell cultures. Learn more at Thermo Fisher Scientific.

Formula: C₆₀H₁₂₅N₁₅O₂₅S

Color and Shape: Powder, White to cream

Molecular weight: 1488.80

Ref: 02-J62834

Gentamicin sulfate

CAS: 1405-41-0

Gentamicin sulfate

Color and Shape: Off-White

Ref: 47-174

GENTAMICIN SULFATE CRS

CAS: 1405-41-0

GENTAMICIN SULFATE CRS

Formula: C₁₉H₄₁N₅O₁₁S

Molecular weight: 547.6207

Ref: 41-G0200000

SECOND INTERNATIONAL STANDARD FOR GENTAMICIN

CAS: 1405-41-0

SECOND INTERNATIONAL STANDARD FOR GENTAMICIN

Formula: C₁₉H₄₁N₅O₁₁S

Molecular weight: 547.6207

Ref: 41-ISA_92_670

GENTAMICIN SULFATE RS

CAS: 1405-41-0

GENTAMICIN SULFATE RS

Formula: C₁₉H₄₁N₅O₁₁S

Molecular weight: 547.6207

Ref: 41-ICRS0319

GENTAMICIN FOR PEAK IDENTIFICATION CRS

CAS: 1405-41-0

GENTAMICIN FOR PEAK IDENTIFICATION CRS

Formula: C₁₉H₄₁N₅O₁₁S

Molecular weight: 547.6207

Ref: 41-Y0001363

Gentamicin Sulfate

CAS: 1405-41-0

Antibiotics nesoi

Formula: NA(mixture)

Color and Shape: Off-White White Powder

Molecular weight: 547.6207

Ref: 45-1289003

Gentamicin, sulfate (salt)

CAS: 1405-41-0

Formula: C₆₀H₁₂₅N₁₅O₂₅S

Color and Shape: Solid

Molecular weight: 1488.7850

Ref: IN-DA00384E

Gentamicin sulfate

CAS: 1405-41-0

Gentamicin sulfate (SCH9724) is a wide-spectrum, aminoglycoside antibiotic used to inhibit protein synthesis in sensitive organisms.

Formula: C₆₀H₁₂₇N₁₅O₂₆S

Purity: 99.93%

Color and Shape: White To Buff-Colored Powder Odorless

Molecular weight: 1506.8

Ref: TM-T1326

Gentamicin Sulphate Solution (100 mg/ml)

CAS: 1405-41-0

Gentamicin Sulphate Solution (100 mg/ml)

Molecular weight: 1,488.78g/mol

Ref: 54-BIG0123

Gentamicin sulfate

CAS: 1405-41-0

Formula: C₆₀H₁₂₇N₁₅O₂₆S

Color and Shape: White to off-white powder

Molecular weight: 575.67

Ref: 7W-GA7939

Gentamicin sulphate

CAS: 1405-41-0

Gentamicin sulphate

Formula: C₂₁H₄₃N₅O₇·H₂SO₄

Purity: Ph 4.8 specific optical (Typical Value in Batch COA)

Color and Shape: white to off white powder

Molecular weight: 1,530.86g/mol

Ref: 54-BIG0124

Gentamycin sulfate

Controlled Product

CAS: 1405-41-0

Formula: C₂₁H₄₃N₅O₇·C₂₀H₄₁N₅O₇·C₁₉H₃₉N₅O₇·H₂O₄S

Color and Shape: Neat

Molecular weight: 1487.86918

Ref: 04-C14000200

Gentamycin Sulfate

CAS: 1405-41-0

Ref: 4Z-G-044007

Gentamicin Deuterated (C Complex) Pentaacetate Salt (Contains d0)

Controlled Product

CAS: 1405-41-0

Stability Very Hygroscopic
Applications Inhibits protein synthesis by binding to L6 protein of 50S ribosomal subunit. Antibacterial.Antibiotic complex consists of three closely related components, gentamicins C1, C2, C1a, and also gentamicin A which differs from the other members of the complex but is similar to Kanamycin C.Gentamicin C1: R1=R2=CH3Gentamicin C2: R1=CH3; R2=HGentamicin C1A: R1=R2=H
References Holt, H.A., et al.: J. Antimicrob. Chemother., 34, 747 (1994), Wilschanski, M., et al.: Am. J. Respir. Crit. Care Med., 161, 860 (2000),

Formula: C₅H₅NO₃

Color and Shape: Neat

Molecular weight: NA

Ref: TR-G360602

Gentamicin Sulfate Salt (C Complex)

CAS: 1405-41-0

Formula: C₅H₅NO₃

Color and Shape: Off-White

Ref: TR-G360600

Gentamycin sulfate, Antibiotic for Culture Media Use Only

CAS: 1405-41-0

Gentamycin sulphate is the salt form of the broad-spectrum antibiotic gentamycin (a.k.a. gentamicin). Gentamycin is active against clinically relevant bacteria, such as: Pseudomonas aeruginosa, Klebsiella pneumoniae, Escherichia coli, Serratia marcescens, and is used to fight infections from Staphylococcus, Citrobacter and Enterobacteriaceae species. Gentamycin is a natural mixture of four congeners, one of which is gentamicin C2a. Gentamycin has been included in biomedical implantable materials, such as, bone grafts, to reduce the risk of infection.

Formula: C₂₁H₄₅N₅O₁₁S

Molecular weight: 575.67 g/mol

Ref: 3D-G-2420

Gentamycin sulphate

CAS: 1405-41-0

Gentamycin sulphate is the salt form of the broad-spectrum antibiotic gentamycin (a.k.a. gentamicin). Gentamycin is active against clinically relevant bacteria, such as: Pseudomonas aeruginosa, Klebsiella pneumoniae, Escherichia coli, Serratia marcescens, and is used to fight infections from Staphylococcus, Citrobacter and Enterobacteriaceae species. Gentamycin is a natural mixture of four congeners, one of which is gentamicin C2a. Gentamycin has been included in biomedical implantable materials, such as, bone grafts, to reduce the risk of infection.

Formula: C₂₁H₄₃N₅O₇·H₂SO₄

Color and Shape: White Powder

Molecular weight: 575.68 g/mol

Ref: 3D-AG29671