CAS 1405-86-3

glycyrrhizic acid

Description:

Glycyrrhizic acid, with the CAS number 1405-86-3, is a natural compound derived from the root of the licorice plant (Glycyrrhiza glabra). It is a triterpenoid saponin, characterized by its sweet taste, which is significantly sweeter than sucrose. Glycyrrhizic acid exhibits various biological activities, including anti-inflammatory, antiviral, and hepatoprotective properties, making it of interest in both traditional medicine and modern pharmacology. The compound is soluble in water and alcohol, but its solubility can vary depending on pH and temperature. Glycyrrhizic acid can also influence cortisol metabolism, which is why it is important to monitor its consumption, as excessive intake may lead to side effects such as hypertension and hypokalemia. Additionally, it is often used as a flavoring agent in food products and as a sweetener in herbal formulations. Its safety profile is generally favorable when consumed in moderation, but caution is advised in individuals with certain health conditions.

Formula: C₄₂H₆₂O₁₆

InChI: InChI=1/C41H60O16.3H3N/c1-37(2)21-8-11-40(5)18-7-10-38(3)13-14-39(4,36(52)53)16-19(38)17(18)15-20(42)31(40)41(21,6)12-9-22(37)54-34-27(47)25(45)28(30(57-34)33(50)51)55-35-26(46)23(43)24(44)29(56-35)32(48)49;;;/h15,18-19,21-31,34-35,43-47H,7-14,16H2,1-6H3,(H,48,49)(H,50,51)(H,52,53);3*1H3/t18?,19-,21?,22-,23-,24-,25+,26+,27+,28-,29-,30-,31?,34+,35+,38-,39-,40-,41-;;;/m0.../s1

InChI key: InChIKey=LPLVUJXQOOQHMX-QWBHMCJMSA-N

SMILES: C[C@]12[C@@]([C@]3(C)[C@@](CC1)(C(C)(C)[C@@H](O[C@@H]4[C@H](O[C@@H]5O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]5O)[C@@H](O)[C@H](O)[C@@H](C(O)=O)O4)CC3)[H])(C(=O)C=C6[C@@]2(C)CC[C@]7(C)[C@]6(C[C@](C(O)=O)(C)CC7)[H])[H]

Synonyms:

• (3beta)-30-hydroxy-11,30-dioxoolean-12-en-3-yl 2-O-beta-D-glucopyranuronosyl-alpha-D-glucopyranosiduronic acid
• (3β,20β)-20-Carboxy-11-oxo-30-norolean-12-en-3-yl 2-O-β-<span class="text-smallcaps">D</smallcap>-glucopyranuronosyl-α-<smallcap>D</span>-glucopyranosiduronic acid
• 18β-Glycyrrhizic acid
• 18β-Glycyrrhizinic acid
• 30-Noroleanane, α-<span class="text-smallcaps">D</span>-glucopyranosiduronic acid deriv.
• Acide glycyrrhizique
• Acido Glicirricico
• Gancaotiansu
• Glycyron
• Glycyrrhetinic acid glycoside
• Glycyrrhizin
• Glycyrrhizinic Acid
• Glycyrrhizinsaure
• Liquorice Root P.E.
• Nsc 167409
• Nsc 234419
• Potenlini
• triammonium (2S,3S,4R,5R,6R)-6-[[(3S,6aS,8aS,11S,12aR,14bS)-11-carboxylato-4,4,6a,8a,11,14b-hexamethyl-14-oxo-1,2,3,4a,5,6,6b,7,8,9,10,12,12a,14a-tetradecahydropicen-3-yl]oxy]-3-[(2R,3R,4S,5S,6S)-6-carboxylato-3,4,5-trihydroxy-tetrahydropyran-2-yl]oxy-4,5-dihydroxy-tetrahydropyran-2-carboxylate
• α-<span class="text-smallcaps">D</smallcap>-Glucopyranosiduronic acid, (3β,20β)-20-carboxy-11-oxo-30-norolean-12-en-3-yl 2-O-β-<smallcap>D</span>-glucopyranuronosyl-
• α-D-Glucopyranosiduronic acid, (3β,20β)-20-carboxy-11-oxo-30-norolean-12-en-3-yl 2-O-β-D-glucopyranuronosyl-
• β-Glycyrrhizin
• Glycyrrhizic acid
• (3β,20β)-20-Carboxy-11-oxo-30-norolean-12-en-3-yl 2-O-β-D-glucopyranuronosyl-α-D-glucopyranosiduronic acid
• 30-Noroleanane, α-D-glucopyranosiduronic acid deriv.
• (3β,20β)-20-Carboxy-11-oxo-30-norolean-12-en-3-yl 2-O-β-D-Glucopyranuronosyl-α-
• alpha-d-glucopyranosiduronicacid,(3beta,20beta)-20-carboxy-11-oxo-30-norol
• 3-O-(2-O-beta-D-Glucopyranuronosyl-alpha-D-glucopyranuronosyl)-18beta-g lycyrrhetinic acid
• Glycyrrhizinate acid 15-18% (R-19)
• liquorice
• Glycyrrhizinic acid (Glycyrrhizin)
• 20beta-carboxy-11-oxo-30-norolean-12-en-3beta-yl-2-o-beta-d-glucopyranuronosyl
• Glycyrrhisinic acid power 21% W/W
• D-glucopyranosiduronic Acid
• GLYCYRRHIZIC ACID(P)(CALL)
• beta-glycyrrhizin
• Of glycyrrhizin
• (20S)-3β-[(2-O-β-D-Glucopyranuronosyl-α-D-glucopyranuronosyl)oxy]-11-oxoolean-12-en-30-oic acid
• alpha-d-glucopyranosiduronicacid,(3beta,20beta)-20-carboxy-11-oxo-30-norolean
• Glycyrrhizin std.
• .alpha.-D-Glucopyranosiduronic acid, (3.beta.,20.beta.)-20-carboxy-11-oxo-30-norolean-12-en-3-yl 2-O-.beta.-D-glucopyranuronosyl-
• ean-12-en-3-yl2-o-beta-d-glucopyranuronosyl-
• Glycyrrhizic
• Glycyrrhizic Acid (25 mg)
• Glycyrrhizin (Glycyrrhizic Acid)
• (3beta,20beta)-20-Carboxy-11-oxo-30-norlean-12-en-3-yl-2-O-beta-1-7-glucopyranuronosyl-alpha-D-glucopyranosiduronic acid
• 5-[(6-carboxy-3,4,5-trihydroxyoxan-2-yl)oxy]-6-[(11-carboxy-4,4,6a,6b,8a,11,14b-heptaMethyl-14-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicen-3-yl)oxy]-3,4-dihydroxyoxane-2-carboxylic acid
• Glycyrrhizic acid (8CI)
• glycyrrhizinicacid
• glucopyranuronosyl-
• DerMacrin
• GLYCYRRHYCIC ACID
• 18-beta-glycyrrhizicacid
• 3-O-(2-O-β-D-Glucopyranuronosyl-α-D-glucopyranuronosyl)-18β-glycyrrhetinic acid
• Potassium Glycyrrhetate
• Radix Glycyrrhizae
• GLYCYRRHIZIC ACID(P)
• -alpha-d-glucopyranosiduronicacid
• β-D-Glucopyranosiduronic acid, (3β,20β)-20-
• 3-o-(2-o-beta-d-glucopyranuronosyl-alpha-d-glucopyranuronosyl)-18beta-g lycyrrhetinic acid
• (3.beta.,20.beta.)-20-carboxy-11-oxo-30-norolean-12-en-3-yl2-O-.beta.-D-glucopyranuronosyl-.alpha.-D-Glucopyranosiduronicacid
• Glycyrrhizine
• -12-en-3-yl-2-o-beta-d-glucopyranuronosyl-
• glucopyranuronosyl-.alpha.-D-Glucopyranosiduronic acid
• carboxy-11-oxo-30-norolean-12-en-3-yl 2-O-β-D-
• glycyrrhizic acid A
• Glycyrrhitin

Glycyrrhizin

CAS: 1405-86-3

Formula: C₄₂H₆₂O₁₆

Purity: >75.0%(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 822.94

Ref: 3B-G0150

Glycyrrhizic acid

CAS: 1405-86-3

Glycyrrhizic acid analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Formula: C₄₂H₆₂O₁₆

Purity: (HPLC) ≥98%

Color and Shape: Powder

Molecular weight: 822.95

Ref: 11-2319S

Glycyrrhizic Acid

CAS: 1405-86-3

Other glycosides, natural or reproduced by synthesis, and their salts, ethers, esters and other derivatives

Formula: C₄₂H₆₂O₁₆

Color and Shape: White Off-White Powder

Molecular weight: 822.40379

Ref: 45-1295888

Glycyrrhizic Acid

CAS: 1405-86-3

Formula: C₄₂H₆₂O₁₆

Color and Shape: White To Off-White Solid

Molecular weight: 822.94

Ref: 4Z-G-045001

Glycyrrhizic acid

CAS: 1405-86-3

Formula: C₄₂H₆₂O₁₆·NH₃

Purity: ≥ 95.0%

Color and Shape: White to off-white or faint yellow powder

Molecular weight: 839.96

Ref: 7W-GC9316

Glycyrrhizic acid

CAS: 1405-86-3

Glycyrrhizic acid

Purity: ≥95%

Molecular weight: 822.93g/mol

Ref: 54-BUP16700

Glycyrrhizic acid

Controlled Product

CAS: 1405-86-3

Formula: C₄₂H₆₂O₁₆

Color and Shape: Neat

Molecular weight: 822.93

Ref: 04-C14039000

Glycyrrhizic acid

CAS: 1405-86-3

Glycyrrhizic acid has immunoregulatory function,it(up to 100 mg/ml) can inhibit interleukin-6 and elevate interleukin-10 production in lipopolysaccharide-activated macrophages, and significantly inhibit proliferation of spleen lymphocytes; rectally administered glycyrrhizic acid has significant protective effects against TNBS-induced colitis in rats.

Formula: C₄₂H₆₂O₁₆

Purity: 95%~99%

Color and Shape: Powder

Molecular weight: 822.942

Ref: BP-BP0682

Glycyrrhizic acid

CAS: 1405-86-3

Glycyrrhizic acid (Glycyrrhizin), the active ingredient in licorice, is a triterpene saponins and an antagonist of HMGB1. High-Quality, Low-Cost!

Formula: C₄₂H₆₂O₁₆

Purity: 97.51% - 99.74%

Color and Shape: Crystals From Glacial Acetic Acid Crystals From Glacial Acetic Acid Obtained From Licorice

Molecular weight: 822.93

Ref: TM-T2741

Glycyrrhizic Acid RS

CAS: 1405-86-3

Color and Shape: White Solid Powder

Ref: 2K-1048000021

Glycyrrhizin

CAS: 1405-86-3

Glycyrrhizin

Formula: C₄₂H₆₂O₁₆

Purity: ≥ 95.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 822.95

Ref: 5G-89217

Glycyrrhizic Acid

CAS: 1405-86-3

Stability Hygroscopic
Applications Glycyrrhizic Acid is a triterpene saponin used in the traditional Chinese medicinal preparation for its anti-inflammatory, antiulcerous and antiallergic effects.
References Marsh, L., et al.: Biochem. J., 63, 9 (1956), Kitagawa, et al.: Chem. Pharm. Bull., 36, 3710 (1988),

Formula: C₄₂H₆₂O₁₆

Color and Shape: White To Light Beige

Molecular weight: 822.93

Ref: TR-G735150

Glycyrrhizic acid - 80%

CAS: 1405-86-3

Glycyrrhizic acid is the major bioactive triterpene glycoside of licorice. In mice, glycyrrhizic acid modulates the gut microbiota counteracting a high fat diet. In rats, it has shown an anti-inflammatory activity that resulted in cardioprotective action against myocardial ischemia. In humans, it is a promising adjuvant in the treatment of depression.

Formula: C₄₂H₆₂O₁₆

Purity: Min. 95%

Color and Shape: White Off-White Powder

Molecular weight: 822.93 g/mol

Ref: 3D-OG08293

Glycyrrhizic acid - 98%

CAS: 1405-86-3

Glycyrrhizic acid is the major bioactive triterpene glycoside of licorice. In mice, glycyrrhizic acid modulates the gut microbiota counteracting a high fat diet. In rats, glycyrrhizic acid has shown an anti-inflammatory activity that resulted in cardioprotective action against myocardial ischemia. In humans, glycyrrhizic acid is a promising adjuvant in the treatment of depression.

Formula: C₄₂H₆₂O₁₆

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 822.93 g/mol

Ref: 3D-XG180042

Glycyrrhizic Acid-d3

Controlled Product

CAS: 1405-86-3

Formula: C₄₂H₅₉D₃O₁₆

Color and Shape: Neat

Molecular weight: 825.95

Ref: TR-G735152

α-D-Glucopyranosiduronic acid, (3β,20β)-20-carboxy-11-oxo-30-norolean-12-en-3-yl 2-O-β-D-glucopyranuronosyl-

CAS: 1405-86-3

Formula: C₄₂H₆₂O₁₆

Color and Shape: Solid

Molecular weight: 822.9321

Ref: IN-DA001CJT