CAS 1405-86-3
:glycyrrhizic acid
Description:
Glycyrrhizic acid, with the CAS number 1405-86-3, is a natural compound derived from the root of the licorice plant (Glycyrrhiza glabra). It is a triterpenoid saponin, characterized by its sweet taste, which is significantly sweeter than sucrose. Glycyrrhizic acid exhibits various biological activities, including anti-inflammatory, antiviral, and hepatoprotective properties, making it of interest in both traditional medicine and modern pharmacology. The compound is soluble in water and alcohol, but its solubility can vary depending on pH and temperature. Glycyrrhizic acid can also influence cortisol metabolism, which is why it is important to monitor its consumption, as excessive intake may lead to side effects such as hypertension and hypokalemia. Additionally, it is often used as a flavoring agent in food products and as a sweetener in herbal formulations. Its safety profile is generally favorable when consumed in moderation, but caution is advised in individuals with certain health conditions.
Formula:C42H62O16
InChI:InChI=1/C41H60O16.3H3N/c1-37(2)21-8-11-40(5)18-7-10-38(3)13-14-39(4,36(52)53)16-19(38)17(18)15-20(42)31(40)41(21,6)12-9-22(37)54-34-27(47)25(45)28(30(57-34)33(50)51)55-35-26(46)23(43)24(44)29(56-35)32(48)49;;;/h15,18-19,21-31,34-35,43-47H,7-14,16H2,1-6H3,(H,48,49)(H,50,51)(H,52,53);3*1H3/t18?,19-,21?,22-,23-,24-,25+,26+,27+,28-,29-,30-,31?,34+,35+,38-,39-,40-,41-;;;/m0.../s1
InChI key:InChIKey=LPLVUJXQOOQHMX-QWBHMCJMSA-N
SMILES:C[C@]12[C@@]([C@]3(C)[C@@](CC1)(C(C)(C)[C@@H](O[C@@H]4[C@H](O[C@@H]5O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]5O)[C@@H](O)[C@H](O)[C@@H](C(O)=O)O4)CC3)[H])(C(=O)C=C6[C@@]2(C)CC[C@]7(C)[C@]6(C[C@](C(O)=O)(C)CC7)[H])[H]
Synonyms:- (3beta)-30-hydroxy-11,30-dioxoolean-12-en-3-yl 2-O-beta-D-glucopyranuronosyl-alpha-D-glucopyranosiduronic acid
- (3β,20β)-20-Carboxy-11-oxo-30-norolean-12-en-3-yl 2-O-β-<span class="text-smallcaps">D</smallcap>-glucopyranuronosyl-α-<smallcap>D</span>-glucopyranosiduronic acid
- 18β-Glycyrrhizic acid
- 18β-Glycyrrhizinic acid
- 30-Noroleanane, α-<span class="text-smallcaps">D</span>-glucopyranosiduronic acid deriv.
- Acide glycyrrhizique
- Acido Glicirricico
- Gancaotiansu
- Glycyron
- Glycyrrhetinic acid glycoside
- Glycyrrhizin
- Glycyrrhizinic Acid
- Glycyrrhizinsaure
- Liquorice Root P.E.
- Nsc 167409
- Nsc 234419
- Potenlini
- triammonium (2S,3S,4R,5R,6R)-6-[[(3S,6aS,8aS,11S,12aR,14bS)-11-carboxylato-4,4,6a,8a,11,14b-hexamethyl-14-oxo-1,2,3,4a,5,6,6b,7,8,9,10,12,12a,14a-tetradecahydropicen-3-yl]oxy]-3-[(2R,3R,4S,5S,6S)-6-carboxylato-3,4,5-trihydroxy-tetrahydropyran-2-yl]oxy-4,5-dihydroxy-tetrahydropyran-2-carboxylate
- α-<span class="text-smallcaps">D</smallcap>-Glucopyranosiduronic acid, (3β,20β)-20-carboxy-11-oxo-30-norolean-12-en-3-yl 2-O-β-<smallcap>D</span>-glucopyranuronosyl-
- α-D-Glucopyranosiduronic acid, (3β,20β)-20-carboxy-11-oxo-30-norolean-12-en-3-yl 2-O-β-D-glucopyranuronosyl-
- β-Glycyrrhizin
- Glycyrrhizic acid
- (3β,20β)-20-Carboxy-11-oxo-30-norolean-12-en-3-yl 2-O-β-D-glucopyranuronosyl-α-D-glucopyranosiduronic acid
- 30-Noroleanane, α-D-glucopyranosiduronic acid deriv.
- (3β,20β)-20-Carboxy-11-oxo-30-norolean-12-en-3-yl 2-O-β-D-Glucopyranuronosyl-α-
- alpha-d-glucopyranosiduronicacid,(3beta,20beta)-20-carboxy-11-oxo-30-norol
- 3-O-(2-O-beta-D-Glucopyranuronosyl-alpha-D-glucopyranuronosyl)-18beta-g lycyrrhetinic acid
- Glycyrrhizinate acid 15-18% (R-19)
- liquorice
- Glycyrrhizinic acid (Glycyrrhizin)
- 20beta-carboxy-11-oxo-30-norolean-12-en-3beta-yl-2-o-beta-d-glucopyranuronosyl
- Glycyrrhisinic acid power 21% W/W
- D-glucopyranosiduronic Acid
- GLYCYRRHIZIC ACID(P)(CALL)
- beta-glycyrrhizin
- Of glycyrrhizin
- (20S)-3β-[(2-O-β-D-Glucopyranuronosyl-α-D-glucopyranuronosyl)oxy]-11-oxoolean-12-en-30-oic acid
- alpha-d-glucopyranosiduronicacid,(3beta,20beta)-20-carboxy-11-oxo-30-norolean
- Glycyrrhizin std.
- .alpha.-D-Glucopyranosiduronic acid, (3.beta.,20.beta.)-20-carboxy-11-oxo-30-norolean-12-en-3-yl 2-O-.beta.-D-glucopyranuronosyl-
- ean-12-en-3-yl2-o-beta-d-glucopyranuronosyl-
- Glycyrrhizic
- Glycyrrhizic Acid (25 mg)
- Glycyrrhizin (Glycyrrhizic Acid)
- (3beta,20beta)-20-Carboxy-11-oxo-30-norlean-12-en-3-yl-2-O-beta-1-7-glucopyranuronosyl-alpha-D-glucopyranosiduronic acid
- 5-[(6-carboxy-3,4,5-trihydroxyoxan-2-yl)oxy]-6-[(11-carboxy-4,4,6a,6b,8a,11,14b-heptaMethyl-14-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicen-3-yl)oxy]-3,4-dihydroxyoxane-2-carboxylic acid
- Glycyrrhizic acid (8CI)
- glycyrrhizinicacid
- glucopyranuronosyl-
- DerMacrin
- GLYCYRRHYCIC ACID
- 18-beta-glycyrrhizicacid
- 3-O-(2-O-β-D-Glucopyranuronosyl-α-D-glucopyranuronosyl)-18β-glycyrrhetinic acid
- Potassium Glycyrrhetate
- Radix Glycyrrhizae
- GLYCYRRHIZIC ACID(P)
- -alpha-d-glucopyranosiduronicacid
- β-D-Glucopyranosiduronic acid, (3β,20β)-20-
- 3-o-(2-o-beta-d-glucopyranuronosyl-alpha-d-glucopyranuronosyl)-18beta-g lycyrrhetinic acid
- (3.beta.,20.beta.)-20-carboxy-11-oxo-30-norolean-12-en-3-yl2-O-.beta.-D-glucopyranuronosyl-.alpha.-D-Glucopyranosiduronicacid
- Glycyrrhizine
- -12-en-3-yl-2-o-beta-d-glucopyranuronosyl-
- glucopyranuronosyl-.alpha.-D-Glucopyranosiduronic acid
- carboxy-11-oxo-30-norolean-12-en-3-yl 2-O-β-D-
- glycyrrhizic acid A
- Glycyrrhitin
- See more synonyms
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Glycyrrhizin
CAS:Formula:C42H62O16Purity:>75.0%(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:822.94Glycyrrhizic Acid
CAS:Other glycosides, natural or reproduced by synthesis, and their salts, ethers, esters and other derivativesFormula:C42H62O16Color and Shape:White Off-White PowderMolecular weight:822.40379Glycyrrhizic acid
CAS:Glycyrrhizic acidFormula:C42H62O16Purity:99.5%Color and Shape:SolidMolecular weight:822.93Glycyrrhizic Acid
CAS:Formula:C42H62O16Color and Shape:White To Off-White SolidMolecular weight:822.94Glycyrrhizic acid
CAS:Formula:C42H62O16Purity:≥ 95.0%Color and Shape:White to off-white or faint yellow powderMolecular weight:822.9Glycyrrhizic acid
CAS:Glycyrrhizic acid analytical standard provided with w/w absolute assay, to be used for quantitative titration.Formula:C42H62O16Purity:(HPLC) ≥98%Color and Shape:PowderMolecular weight:822.95Glycyrrhizic acid (Standard)
CAS:Glycyrrhizic acid (Standard) is a reference standard for research and analysis in studies involving Glycyrrhizic acid. Glycyrrhizic acid (Glycyrrhizin), the active ingredient in licorice, is a triterpene saponins and an antagonist of HMGB1. Glycyrrhizic acid has the potential to be used in cancer, diabetes and other research.Formula:C42H62O16Molecular weight:822.9321Glycyrrhizic acid
CAS:Glycyrrhizic acid has immunoregulatory function,it(up to 100 mg/ml) can inhibit interleukin-6 and elevate interleukin-10 production in lipopolysaccharide-activated macrophages, and significantly inhibit proliferation of spleen lymphocytes; rectally administered glycyrrhizic acid has significant protective effects against TNBS-induced colitis in rats.Formula:C42H62O16Purity:95%~99%Color and Shape:PowderMolecular weight:822.942Glycyrrhizic Acid
CAS:Stability Hygroscopic
Applications Glycyrrhizic Acid is a triterpene saponin used in the traditional Chinese medicinal preparation for its anti-inflammatory, antiulcerous and antiallergic effects.
References Marsh, L., et al.: Biochem. J., 63, 9 (1956), Kitagawa, et al.: Chem. Pharm. Bull., 36, 3710 (1988),Formula:C42H62O16Color and Shape:NeatMolecular weight:822.93(2S,3S,4S,5R,6R)-6-(((2S,3R,4S,5S,6S)-6-Carboxy-2-(((3S,6aR,6bS,8aS,11S,12aR,14aR,14bS)-11-carboxy-4,4,6a,6b,8a,11,14b-heptamethyl-14-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicen-3-yl)oxy)-4,5-dihydroxytetrahydro-2H-pyran-3-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid
CAS:Formula:C42H62O16Purity:80% HPLCMolecular weight:822.93Glycyrrhizic acid
CAS:Glycyrrhizic acid (Glycyrrhizin), the active ingredient in licorice, is a triterpene saponins and an antagonist of HMGB1. High-Quality, Low-Cost!Formula:C42H62O16Purity:97.51% - 99.74%Color and Shape:White SolidMolecular weight:822.9321Glycyrrhizin
CAS:GlycyrrhizinFormula:C42H62O16Purity:≥ 95.0 % (HPLC)Color and Shape:PowderMolecular weight:822.95Glycyrrhizic acid - 80%
CAS:Glycyrrhizic acid is the major bioactive triterpene glycoside of licorice. In mice, glycyrrhizic acid modulates the gut microbiota counteracting a high fat diet. In rats, it has shown an anti-inflammatory activity that resulted in cardioprotective action against myocardial ischemia. In humans, it is a promising adjuvant in the treatment of depression.Formula:C42H62O16Purity:Min. 95%Color and Shape:White Off-White PowderMolecular weight:822.93 g/molGlycyrrhizic acid - 98%
CAS:Glycyrrhizic acid is the major bioactive triterpene glycoside of licorice. In mice, glycyrrhizic acid modulates the gut microbiota counteracting a high fat diet. In rats, glycyrrhizic acid has shown an anti-inflammatory activity that resulted in cardioprotective action against myocardial ischemia. In humans, glycyrrhizic acid is a promising adjuvant in the treatment of depression.
Formula:C42H62O16Purity:Min. 98 Area-%Color and Shape:PowderMolecular weight:822.93 g/mol
