CAS 141283-87-6

N-[2-[(Ethylsulfonyl)amino]-5-(trifluoromethyl)-3-pyridinyl]cyclohexanecarboxamide

Description:

N-[2-[(Ethylsulfonyl)amino]-5-(trifluoromethyl)-3-pyridinyl]cyclohexanecarboxamide, with the CAS number 141283-87-6, is a chemical compound characterized by its complex structure, which includes a pyridine ring substituted with a trifluoromethyl group and an ethylsulfonylamino moiety. This compound features a cyclohexanecarboxamide group, contributing to its potential biological activity. The presence of the trifluoromethyl group often enhances lipophilicity and metabolic stability, while the ethylsulfonyl group can influence solubility and reactivity. The compound's structural features suggest potential applications in medicinal chemistry, particularly in the development of pharmaceuticals targeting specific biological pathways. Its unique combination of functional groups may impart specific pharmacological properties, making it a candidate for further research in drug development. As with many compounds, its safety, efficacy, and environmental impact would need to be thoroughly evaluated in accordance with regulatory standards before any practical applications.

Formula: C₁₅H₂₀F₃N₃O₃S

InChI: InChI=1S/C15H20F3N3O3S/c1-2-25(23,24)21-13-12(8-11(9-19-13)15(16,17)18)20-14(22)10-6-4-3-5-7-10/h8-10H,2-7H2,1H3,(H,19,21)(H,20,22)

InChI key: InChIKey=TUWCZRFHNIOVTC-UHFFFAOYSA-N

SMILES: N(C(=O)C1CCCCC1)C2=C(NS(CC)(=O)=O)N=CC(C(F)(F)F)=C2

Synonyms:

• IS 741
• Cyclohexanecarboxamide, N-[2-[(ethylsulfonyl)amino]-5-(trifluoromethyl)-3-pyridinyl]-
• N-[2-[(Ethylsulfonyl)amino]-5-(trifluoromethyl)-3-pyridinyl]cyclohexanecarboxamide
• Fuzapladib

Fuzapladib

CAS: 141283-87-6

Fuzapladib (IS-741) is a PLA2 inhibitor that reduces Mac-1 expression to prevent inflammation and pancreatitis.

Formula: C₁₅H₂₀F₃N₃O₃S

Purity: 99.87%

Color and Shape: Solid

Molecular weight: 379.4

Ref: TM-T67749

Cyclohexanecarboxamide, N-[2-[(ethylsulfonyl)amino]-5-(trifluoromethyl)-3-pyridinyl]-

CAS: 141283-87-6

Formula: C₁₅H₂₀F₃N₃O₃S

Purity: 98%

Color and Shape: Solid

Molecular weight: 379.3978

Ref: IN-DA001G6A

Fuzapladib

CAS: 141283-87-6

Fuzapladib

Formula: C₁₅H₂₀F₃N₃O₃S

Purity: ≥98%

Molecular weight: 379.4

Ref: 54-BUP06960