CAS 14148-44-8

N-Methyl-8-quinolinamine

Description:

N-Methyl-8-quinolinamine, with the CAS number 14148-44-8, is an organic compound characterized by its quinoline structure, which consists of a bicyclic aromatic system containing a nitrogen atom. This compound features a methyl group attached to the nitrogen of the amino group at the 8-position of the quinoline ring. It is typically a solid at room temperature and exhibits properties common to nitrogen-containing heterocycles, such as potential basicity due to the presence of the amino group. N-Methyl-8-quinolinamine may display fluorescence, making it useful in various applications, including as a fluorescent probe in biochemical assays. Its chemical reactivity can be influenced by the presence of the quinoline moiety, which can participate in electrophilic substitution reactions. Additionally, this compound may have implications in medicinal chemistry, as quinoline derivatives are often explored for their biological activities, including antimicrobial and antitumor properties. Safety data should be consulted for handling and usage, as with any chemical substance.

Formula: C₁₀H₁₀N₂

InChI: InChI=1S/C10H10N2/c1-11-9-6-2-4-8-5-3-7-12-10(8)9/h2-7,11H,1H3

InChI key: InChIKey=NVDZAZXIBALFGT-UHFFFAOYSA-N

SMILES: N(C)C=1C2=C(C=CC1)C=CC=N2

Synonyms:

• 8-Quinolinamine, N-methyl-
• 8-(Methylamino)quinoline
• Quinoline, 8-(methylamino)-
• N-Methyl-8-quinolinamine

N-Methyl-8-quinolinamine

CAS: 14148-44-8

Formula: C₁₀H₁₀N₂

Purity: 97%

Color and Shape: Liquid

Molecular weight: 158.1998

Ref: IN-DA01B7TL

N-methylquinolin-8-amine

CAS: 14148-44-8

N-methylquinolin-8-amine

Formula: C₁₀H₁₀N₂

Purity: 98%

Molecular weight: 158.2

Ref: 54-OR78086

N-Methylquinolin-8-amine

CAS: 14148-44-8

Purity: 98%

Molecular weight: 158.2039948

Ref: 10-F867098

N-Methylquinolin-8-amine

CAS: 14148-44-8

N-Methylquinolin-8-amine (NMQ) is a cytosolic calcium ionophore, which is a drug target for the treatment of HIV infections. NMQ binds to the cytosolic calcium channels and potently inhibits the release of this ion from the cells. It also has stereoselective binding to phenyl groups and terminal alkynes. This drug has been shown to have anti-cancer properties in vitro and in vivo, as well as chemokine inhibition. The synthesis of NMQ was achieved by reacting aniline with chloroacetaldehyde followed by quinolinoyl chloride and then methylation with methyl iodide.

Formula: C₁₀H₁₀N₂

Purity: Min. 95%

Molecular weight: 158.2 g/mol

Ref: 3D-PAA14844